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Baclofen 2%/Diclofenac Sodium 4%/Lidocaine 4%/Verapamil HCl 8% Topical Gel

This formulation is a semisolid, gel-like compound containing Baclofen 2%, Diclofenac Sodium 4%, Lidocaine 4%, and Verapamil HCl 8%. It is dispensed through a pump mechanism, allowing for easy and precise application on the skin. The active ingredients in this formulation work together to provide targeted treatment for a variety of disease states.

Baclofen is a muscle relaxant and antispastic agent, used to alleviate symptoms associated with muscle spasms and tightness. Diclofenac Sodium is a nonsteroidal anti-inflammatory drug (NSAID) that helps reduce pain, inflammation, and joint stiffness caused by arthritis. Lidocaine is a local anesthetic that provides temporary relief from pain and discomfort. Verapamil HCl is a calcium channel blocker that can treat high blood pressure, chest pain (angina), and certain heart rhythm disorders.

Together, these ingredients create a potent topical gel designed to provide relief from pain, inflammation, muscle spasms, and certain cardiovascular conditions. The pump mechanism allows for easy and precise application, ensuring the active ingredients are delivered directly to the affected area for targeted treatment.

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Topical Gel
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Formula Information

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This formulation is a compounded topical gel containing Baclofen 2%, Diclofenac Sodium 4%, Lidocaine 4%, and Verapamil HCl 8%. It is a semisolid formulation that is dispensed through a pump mechanism, which allows for easy and precise application on the skin. The gel-like consistency ensures that the active ingredients are absorbed effectively for targeted treatment.

Baclofen is a muscle relaxant and antispastic agent that helps to relieve muscle spasms, tightness, and pain. Diclofenac Sodium is a nonsteroidal anti-inflammatory drug (NSAID) that reduces pain and inflammation by inhibiting the production of prostaglandins, substances in the body that cause pain and inflammation. Lidocaine is a local anesthetic that works by blocking nerve signals in your body, providing temporary relief of pain and discomfort. Verapamil HCl is a calcium channel blocker that relaxes the muscles of your heart and blood vessels, which can help to improve blood flow and reduce heart rate.

This combination of active ingredients makes the formulation effective in treating a variety of disease states. It can be used to manage pain and inflammation associated with conditions such as arthritis, muscle spasms, and neuropathic pain. It can also be used to treat symptoms of certain heart conditions, such as angina, by improving blood flow and reducing heart rate.

It is important to use this medication exactly as prescribed by your healthcare provider. Apply the gel to the affected area as directed, usually 3 to 4 times daily. Do not apply more than the recommended dose, as this can increase the risk of side effects. Avoid contact with eyes, nose, mouth, and other sensitive areas. Wash your hands thoroughly after applying the gel.

Side effects may include skin irritation at the application site, such as redness, itching, or rash. If these side effects persist or worsen, or if you experience serious side effects such as severe dizziness, fainting, or slow/irregular heartbeat, seek medical attention immediately.

Before using this medication, inform your healthcare provider if you have any allergies, medical conditions, or if you are taking any other medications, as this can affect the effectiveness and safety of the medication.

If you have any questions about this formulation, please do not hesitate to reach out to us at Bayview Pharmacy. Our knowledgeable team of compounding pharmacists is always here to assist you.

Drug Interactions

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This topical gel formulation contains four active ingredients: Baclofen, Diclofenac Sodium, Lidocaine, and Verapamil HCl. Each of these ingredients has a specific role in managing pain and inflammation, but they may also interact with other medications or medical conditions. It's important to understand these potential interactions before using this product.

Baclofen is a muscle relaxant and antispastic agent. It may interact with other central nervous system depressants like alcohol, benzodiazepines, opioids, and antihistamines, potentially leading to increased sedation or respiratory depression. Patients with kidney disease may also need to use Baclofen with caution, as it is primarily excreted by the kidneys.

Diclofenac Sodium is a nonsteroidal anti-inflammatory drug (NSAID) that can reduce pain and inflammation. It may interact with other NSAIDs, blood thinners, and corticosteroids, increasing the risk of gastrointestinal bleeding. Diclofenac Sodium can also interact with certain blood pressure medications and diuretics, potentially reducing their effectiveness. Patients with heart disease, high blood pressure, or kidney disease should use this medication with caution.

Lidocaine is a local anesthetic that provides temporary numbness or loss of sensation in the area where it's applied. It may interact with other local anesthetics and certain heart medications. Overuse of Lidocaine can lead to systemic toxicity, especially in patients with liver disease, as it is metabolized in the liver.

Verapamil HCl is a calcium channel blocker used to treat high blood pressure and heart conditions. It may interact with other heart medications, certain antibiotics and antifungals, and grapefruit juice. These interactions can lead to changes in heart rhythm, slow heart rate, or excessively low blood pressure. Patients with heart conditions should use this medication under close medical supervision.

This formulation is designed to provide targeted treatment for pain and inflammation, particularly in conditions like arthritis, muscle spasms, and neuropathic pain. However, due to the potential for drug interactions and the specific health considerations associated with each active ingredient, it's important to discuss your full medical history and current medication list with your healthcare provider before starting this treatment.

If you have any questions about this formulation or its potential interactions, please don't hesitate to reach out to us at Bayview Pharmacy. Our team of knowledgeable compounding pharmacists is here to help.

How Does it Work

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This formulation is a combination of four active ingredients: Baclofen, Diclofenac Sodium, Lidocaine, and Verapamil HCl. Each of these ingredients plays a unique role in providing relief from various disease states.

Baclofen is a muscle relaxant and antispasmodic agent. It works by inhibiting the transmission of signals from the nerves to the muscles, thereby reducing muscle spasms and providing relief from pain and discomfort associated with conditions such as multiple sclerosis and spinal cord injuries.

Diclofenac Sodium is a non-steroidal anti-inflammatory drug (NSAID). It works by reducing substances in the body that cause pain and inflammation. This makes it effective in treating conditions like osteoarthritis and rheumatoid arthritis.

Lidocaine is a local anesthetic. It works by blocking nerve signals in your body, thereby numbing the specific area of application. This provides immediate relief from pain and discomfort, making it useful in managing conditions like post-herpetic neuralgia and other types of neuropathic pain.

Verapamil HCl is a calcium channel blocker. It works by relaxing the muscles of your heart and blood vessels. In this topical formulation, it is often used to treat Peyronie's disease, a condition that causes fibrous scar tissue to develop in the penis, leading to curved, painful erections.

The gel formulation allows for easy and precise application of these active ingredients directly to the affected area. This targeted approach not only enhances the effectiveness of the treatment but also minimizes systemic side effects that are often associated with oral administration of these drugs.

It's important to note that while this formulation can provide significant relief from the symptoms of these conditions, it does not cure them. It should be used as part of a comprehensive treatment plan, under the supervision of a healthcare provider.

If you have any questions about this formulation, how it works, or how it can be used to manage specific disease states, please don't hesitate to reach out to us. Our team of knowledgeable compounding pharmacists at Bayview Pharmacy is always here to help.

Other Uses

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Frequently Asked Questions

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What is the purpose of Baclofen 2%/Diclofenac Sodium 4%/Lidocaine 4%/Verapamil HCl 8% Topical Gel?

This compounded topical gel is intended for treatment of localized pain and muscle spasticity or relaxation. Each of the ingredient serves a specific purpose with Baclofen reducing muscle spasms, Lidocaine numbing the area for pain relief, Diclofenac Sodium acting as an anti-inflammatory, and Verapamil HCl aiding in muscle relaxation and pain management.

How should I apply this topical gel?

This compounded formulation is a semisolid gel and dispensed through a pump mechanism. This allows for an easy and precise application. Apply it to the skin over the affected area as directed by your doctor and gently rub in until absorbed.

Can the compounded gel be applied to any part of the body?

It is generally recommended to apply this gel on the area of the body as advised by your healthcare professional. Avoid contact with sensitive areas like eyes, mouth or any open wounds unless directly advised by your healthcare provider.

What should I do in case of any adverse reactions?

If you experience any unexpected side effects such as rash, redness, severe itching or swelling at the application site, discontinue use immediately and contact your healthcare provider for further instructions.

How is the consistency of this compounded formulation?

The consistency of this formulation is similar to a gel, thanks to its semisolid form. This allows for a neat application without the typical mess associated with liquid preparations.

Can this gel be used in conjunction with other medications?

Before using any other medications with this gel, it's crucial to consult your healthcare provider to avoid any potential interactions that could occur.

How long should I use this compounded topical gel?

Use the compounded topical gel for the duration recommended by your healthcare provider. Do not exceed the advised usage without consulting your doctor.

What are the storage conditions for this topical gel?

It is advisable to store the compounded formulation at room temperature, away from heat and direct light. Keep the container tightly closed when it is not in use.

Does the pump mechanism affect the gel’s effectiveness?

No, the pump mechanism is intended to facilitate easy and precise application on the skin. It does not affect the potency of the active ingredients in the gel.

Is a prescription required for this topical gel?

Yes, this compounded formulation is a prescription medication and should be used under the supervision of a healthcare provider.

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Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.

No compounded medications are reviewed by the FDA for safety or efficacy.