This formulation combines Baclofen, Diclofenac Sodium, and Verapamil HCl in a topical gel format. Baclofen is a muscle relaxant and antispasmodic agent, Diclofenac Sodium is a nonsteroidal anti-inflammatory drug (NSAID), and Verapamil HCl is a calcium channel blocker. Together, these active ingredients work synergistically to provide relief from various disease states.

Baclofen 2% helps to relieve muscle spasms and tightness caused by certain nerve disorders. It works by helping to relax the muscles, making it useful in treating conditions such as multiple sclerosis and spinal cord injuries or diseases.

Diclofenac Sodium 3% is an NSAID that works by reducing substances in the body that cause pain and inflammation. It is commonly used to treat mild to moderate pain, or signs and symptoms of osteoarthritis or rheumatoid arthritis.

Verapamil HCl 10% is a calcium channel blocker that works by relaxing the muscles of your heart and blood vessels. In this formulation, it is used off-label to improve the penetration of the other two drugs into the skin, enhancing their effectiveness.

The gel is dispensed through a pump mechanism, which allows for easy and precise application on the skin. This targeted treatment ensures that the active ingredients are delivered directly to the area of discomfort, providing localized relief without the systemic side effects that can occur with oral medications.

It is important to use this medication as directed by your healthcare provider. Apply the gel to the affected area in the amount prescribed, usually 3-4 times daily or as directed by your doctor. Do not apply this medication to broken, damaged, or irritated skin. Avoid contact with eyes and mucous membranes. Wash your hands thoroughly after applying the gel, unless your hands are the area being treated.

As with any medication, this formulation may cause side effects. These can include skin irritation at the application site, dizziness, and nausea. If these effects persist or worsen, contact your healthcare provider immediately.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: asthma, aspirin-sensitive asthma (a history of worsening breathing with runny/stuffy nose after taking aspirin or other NSAIDs), liver disease, stomach/intestine/esophagus problems (such as bleeding, ulcers, recurring heartburn), heart disease (such as history of heart attack), high blood pressure, stroke, blood disorders (such as anemia, bleeding/clotting problems), growths in the nose (nasal polyps).

If you have any questions about this formulation, please do not hesitate to reach out to us at Bayview Pharmacy. Our knowledgeable team of compounding pharmacists is here to assist you.

This compounded formulation contains Baclofen, Diclofenac Sodium, and Verapamil HCl. These active ingredients may interact with other medications, potentially altering their effects. It is crucial to inform your healthcare provider about all the medications you are currently taking, including prescription drugs, over-the-counter products, and dietary supplements.

Baclofen, a muscle relaxant and antispastic agent, may interact with other central nervous system depressants, including alcohol, antihistamines, sedatives, and narcotics, potentially enhancing their sedative effects. Concurrent use with monoamine oxidase inhibitors (MAOIs) may result in increased blood pressure.

Diclofenac Sodium, a nonsteroidal anti-inflammatory drug (NSAID), may interact with anticoagulants, antiplatelet drugs, and other NSAIDs, increasing the risk of bleeding. It may also interact with angiotensin-converting enzyme (ACE) inhibitors, angiotensin II receptor blockers (ARBs), or beta-blockers, potentially reducing their effectiveness. Concurrent use with diuretics may increase the risk of kidney damage. Diclofenac Sodium may also interact with lithium and methotrexate, increasing their levels in the blood.

Verapamil HCl, a calcium channel blocker, may interact with beta-blockers, potentially causing heart failure or abnormal heart rhythms. It may also interact with digoxin, increasing its levels in the blood. Concurrent use with other calcium channel blockers may result in additive effects. Verapamil HCl may also interact with statins, increasing their levels in the blood and the risk of side effects.

This formulation is intended for topical use and is designed to deliver the active ingredients directly to the site of pain or inflammation. It is used to treat conditions such as muscle spasms, pain, and inflammation associated with various musculoskeletal conditions. The inclusion of Verapamil HCl may also help to improve blood flow to the area, potentially enhancing the effects of the other active ingredients.

It is important to use this medication exactly as directed by your healthcare provider. Avoid applying it to broken or irritated skin. Also, avoid contact with the eyes, nose, and mouth. If this medication gets in these areas, rinse with plenty of water. Wash your hands after applying, unless your hands are the treated area.

If you have any questions about this formulation or its potential interactions, please do not hesitate to reach out to us. We are here to help ensure that you receive the most benefit from your medication.

The Baclofen 2%/Diclofenac Sodium 3%/Verapamil HCl 10% Topical Gel is a unique formulation that combines three active ingredients, each with its own mechanism of action, to provide targeted relief from various disease states. This semisolid formulation is dispensed through a pump mechanism, which allows for easy and precise application on the skin. The gel-like consistency ensures that the active ingredients are absorbed effectively into the skin for maximum therapeutic effect.

Baclofen is a muscle relaxant and antispasmodic agent. It works by inhibiting the transmission of reflexes at the spinal level, which can help to reduce muscle spasticity and relieve pain. This makes it particularly useful in conditions where muscle spasms or stiffness are a problem, such as multiple sclerosis or spinal cord injuries.

Diclofenac Sodium is a nonsteroidal anti-inflammatory drug (NSAID) that works by reducing substances in the body that cause pain and inflammation. It is commonly used to treat mild to moderate pain, or signs and symptoms of osteoarthritis or rheumatoid arthritis. When applied topically, Diclofenac Sodium can provide targeted relief from pain and inflammation without the systemic side effects that can occur with oral NSAIDs.

Verapamil HCl is a calcium channel blocker. It works by relaxing the muscles of your heart and blood vessels. In this topical formulation, Verapamil HCl is often used to treat Peyronie's disease, a condition in which scar tissue in the penis causes it to bend or curve. Verapamil HCl can help to break down this scar tissue and reduce the curvature of the penis.

Together, these three active ingredients work synergistically to provide relief from a variety of disease states. The topical application allows for targeted treatment, reducing the risk of systemic side effects and providing relief directly where it is needed most. As with any medication, it is important to use this formulation as directed by your healthcare provider.

If you have any questions about the Baclofen 2%/Diclofenac Sodium 3%/Verapamil HCl 10% Topical Gel, or if you would like more information about how it works, please don't hesitate to reach out to us at Bayview Pharmacy. Our knowledgeable team of compounding pharmacists is always here to help.

This formulation containing Baclofen, Diclofenac Sodium, and Verapamil HCl is primarily used under the direction of a healthcare professional for treating various conditions. However, it may have some other potential applications subject to a physician's discretion. Patients with discomfort from muscle spasms may benefit from this formulation due to the muscle relaxant properties of Baclofen. It may be utilized to help reduce the severity and frequency of these spasms, potentially improving the patient's overall comfort and quality of life.

Additionally, Diclofenac Sodium has anti-inflammatory and analgesic properties. This makes the formulation potentially useful for treating conditions with inflammation and pain beyond those it is typically prescribed for. For example, individuals with arthritis, tendonitis, or other musculoskeletal conditions causing inflammation and pain might find some relief using this gel externally, with physician guidance.

The inclusion of Verapamil HCl, a calcium channel blocker, can make this formulation beneficial in treating specific skin conditions. It might be helpful in some cases of Peyronie’s disease considering the use of topical Verapamil is reported to reduce collagen production and promote collagenase activity. Also, patients with hypertrophic scars or keloids might benefit from this compound due to its potential to restrict fibroblast proliferation.

Please note that any use outside of the intended purpose should always be done under the guidance of a healthcare professional. Every patient's situation is unique, and what works for one person might not work for another. Therefore, the physician must consider the patient's overall condition and other medications before suggesting additional uses.

If you are a patient or a prescriber considering alternative uses for this formulation, we highly recommend discussing your options thoroughly with your healthcare provider. If you have further questions about this or any other formulations, feel free to reach out to our team at Bayview Pharmacy. We have a team of knowledgeable compounding pharmacists who are always here to help.