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Baclofen 2%/Cyclobenzaprine HCl 2%/Diclofenac Sodium 3%/Gabapentin 6%/Lidocaine 2%/Prilocaine 2% Topical Gel

This formulation is a compounded topical gel containing Baclofen 2%, Cyclobenzaprine HCl 2%, Diclofenac Sodium 3%, Gabapentin 6%, Lidocaine 2%, and Prilocaine 2%. It is a semisolid formulation dispensed through a pump mechanism, which allows for easy and precise application on the skin. The gel-like consistency aids in the targeted treatment or absorption of the active ingredients.

The combination of these active ingredients is designed to treat a variety of disease states. Baclofen and Cyclobenzaprine HCl are muscle relaxants used to relieve muscle spasms and pain. Diclofenac Sodium is a nonsteroidal anti-inflammatory drug (NSAID) that reduces pain and inflammation. Gabapentin is used to manage nerve pain. Lidocaine and Prilocaine are local anesthetics that numb the skin and decrease pain sensation.

Together, these ingredients provide a comprehensive approach to pain management, addressing multiple aspects of pain and inflammation. This makes the formulation particularly useful for conditions such as neuropathic pain, musculoskeletal pain, and inflammation.

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Topical Gel
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Formula Information

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This formulation is a compounded topical gel containing Baclofen 2%, Cyclobenzaprine HCl 2%, Diclofenac Sodium 3%, Gabapentin 6%, Lidocaine 2%, and Prilocaine 2%. It is a semisolid formulation dispensed through a pump mechanism, which allows for easy and precise application on the skin. The gel-like consistency ensures targeted treatment or absorption of the active ingredients.

The combination of these active ingredients is designed to address a variety of disease states. Baclofen is a muscle relaxant and antispastic agent that helps to relieve muscle spasms, tightness, and pain. Cyclobenzaprine HCl is another muscle relaxant that works by blocking nerve impulses (or pain sensations) that are sent to your brain. Diclofenac Sodium is a nonsteroidal anti-inflammatory drug (NSAID) that reduces substances in the body that cause pain and inflammation. Gabapentin is an anticonvulsant and nerve pain medication that is often used to treat nerve pain and discomfort. Lidocaine and Prilocaine are local anesthetics that work by causing temporary numbness/loss of feeling in the skin and mucous membranes, thereby reducing pain and discomfort.

This formulation is typically used to treat conditions such as neuropathic pain, musculoskeletal pain, inflammation, and certain types of chronic pain. It is applied topically to the affected area, allowing for targeted treatment and potentially reducing systemic side effects often associated with oral medications. The pump mechanism ensures a precise dose is applied each time, reducing the risk of over or under-dosing.

As with any medication, it is important to use this formulation as directed by your healthcare provider. Side effects may include skin irritation at the application site, dizziness, drowsiness, or dry mouth. If these side effects persist or worsen, contact your healthcare provider immediately. It is also important to inform your healthcare provider of all medications you are currently taking, as this formulation may interact with other drugs.

If you have any questions about this formulation, its use, or its potential side effects, please do not hesitate to reach out to us at Bayview Pharmacy. Our knowledgeable team of compounding pharmacists is here to assist you.

Drug Interactions

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This topical gel formulation contains a combination of Baclofen, Cyclobenzaprine HCl, Diclofenac Sodium, Gabapentin, Lidocaine, and Prilocaine. These active ingredients work synergistically to provide pain relief, muscle relaxation, and anti-inflammatory effects, making it an effective treatment for conditions such as neuropathic pain, muscle spasms, and inflammation associated with various disease states.

However, it's important to be aware of potential drug interactions. Here are some key points to consider:

Baclofen: Baclofen may interact with CNS depressants like opioids, benzodiazepines, and alcohol, potentially enhancing their sedative effects. It's important to use caution when using these substances concurrently with Baclofen.

Cyclobenzaprine HCl: This muscle relaxant can interact with monoamine oxidase inhibitors (MAOIs), causing serious side effects such as high fever, convulsions, and even death. It can also interact with other CNS depressants, enhancing their effects.

Diclofenac Sodium: Diclofenac Sodium may interact with anticoagulants, antiplatelets, and selective serotonin reuptake inhibitors (SSRIs), increasing the risk of gastrointestinal bleeding. It can also interact with other NSAIDs, leading to an increased risk of adverse effects.

Gabapentin: Gabapentin may interact with antacids, reducing its absorption. It's recommended to take Gabapentin at least 2 hours after taking an antacid. Gabapentin can also enhance the effects of CNS depressants.

Lidocaine and Prilocaine: These local anesthetics can interact with other local anesthetics and antiarrhythmic drugs, potentially leading to additive systemic toxicity. They can also interact with sulfonamides, potentially inhibiting the metabolism of the anesthetics.

It's crucial to inform your healthcare provider of all medications you are currently taking, including over-the-counter drugs, supplements, and herbal products, to avoid potential drug interactions. If you experience any unusual symptoms or side effects, contact your healthcare provider immediately.

Remember, this formulation is for topical use only and should not be ingested or applied to open wounds or damaged skin. Always use this medication as directed by your healthcare provider.

If you have any questions or concerns about this formulation or its potential interactions, please don't hesitate to reach out to us at Bayview Pharmacy. Our team of compounding pharmacists is here to assist you.

How Does it Work

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This topical gel formulation combines six active ingredients: Baclofen, Cyclobenzaprine HCl, Diclofenac Sodium, Gabapentin, Lidocaine, and Prilocaine. Each of these ingredients plays a unique role in managing pain and inflammation, making this formulation particularly effective for a variety of disease states.

Baclofen is a muscle relaxant and antispastic agent. It works by inhibiting the transmission of reflexes at the spinal level, which can help to alleviate muscle spasms, pain, and stiffness.

Cyclobenzaprine HCl is another muscle relaxant that works by blocking nerve impulses (or pain sensations) that are sent to your brain. This can help to relieve muscle spasms associated with acute musculoskeletal conditions.

Diclofenac Sodium is a nonsteroidal anti-inflammatory drug (NSAID) that works by reducing substances in the body that cause pain and inflammation. It is often used to treat mild to moderate pain, or signs and symptoms of osteoarthritis or rheumatoid arthritis.

Gabapentin is an anticonvulsant and nerve pain medication. It works by affecting the chemicals and nerves in the body that are involved in the cause of seizures and some types of pain. Gabapentin is used to manage postherpetic neuralgia (nerve pain from herpes zoster or shingles).

Lidocaine and Prilocaine are local anesthetics that work by causing temporary numbness/loss of feeling in the skin and mucous membranes. This can help to reduce pain or discomfort caused by minor skin irritations or procedures.

When applied topically, this formulation allows for targeted treatment, delivering these active ingredients directly to the area of discomfort. The gel-like consistency facilitates easy and precise application, and the pump mechanism ensures that the correct dose is dispensed each time.

This formulation can be used to treat a variety of disease states, including but not limited to muscle spasms, osteoarthritis, rheumatoid arthritis, postherpetic neuralgia, and other conditions associated with pain and inflammation. As with any medication, it is important to use this formulation as directed by a healthcare provider.

If you have any questions about this formulation, its ingredients, or how it works, please don't hesitate to reach out to us at Bayview Pharmacy. Our team of knowledgeable compounding pharmacists is here to help.

Other Uses

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This custom-compounded Baclofen/Cyclobenzaprine/Diclofenac/Gabapentin/Lidocaine/Prilocaine topical gel formulation, despite being primarily prescribed for the management of complex pain syndromes typically associated with neuropathic pain, musculoskeletal disorders, and inflammation, has been used off-label for several other therapeutic applications as well. These include, but are not limited to, postsurgical pain management, localized spasms relief in conditions such as multiple sclerosis or spinal cord injury, and symptomatic relief in certain types of dermal lesions or nerve-related skin disorders.

Given the inclusion of multiple analgesics with different mechanisms of action in this formulation, it may also be recommended for cases of resistant pain, where other monotherapeutic agents have provided insufficient relief. For instance, Baclofen, a muscle relaxant, and Gabapentin, a GABA analogue, may offer additional benefits in neurological causes of pain. Simultaneously, the presence of topical anesthetics, Lidocaine and Prilocaine, makes this formulation potentially viable for procedural uses such as in minor surgical or dermatological procedures for localized numbing.

Furthermore, Diclofenac, a nonsteroidal anti-inflammatory drug (NSAID), can provide added benefit in conditions involving inflammation. Despite these potential additional uses, it is crucial to remember that this medication should always be prescribed and used under the strict supervision of a healthcare professional. Misuse or overuse can lead to serious side effects, including but not limited to dermatological reactions and potential systemic effects.

Your physicians or pharmacists at Bayview Pharmacy are well-equipped to provide further information and decide if this compounded formulation is suitable for your specific needs. If you have additional queries, don't hesitate to reach out to us. The safety of our patients and effective management of their conditions is our utmost priority.

Frequently Asked Questions

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What is this compounded formulation comprising Baclofen, Cyclobenzaprine HCl, Diclofenac Sodium, Gabapentin, Lidocaine, and Prilocaine?

This a topical gel that consists of several medicinal compounds like Baclofen, Cyclobenzaprine HCl, Diclofenac Sodium, Gabapentin, Lidocaine, and Prilocaine. It is created to alleviate varying symptoms and is applied on the skin for targeted treatment.

What does the percentage signify in each component of this formulation?

The percentage alongside each component refers to the concentration of each component in the gel. For instance, Baclofen 2% means the gel contains 2% Baclofen by weight.

What makes this formulation a "semisolid"?

A semisolid formulation means the consistency of this gel is neither completely solid, nor fully liquid. It has a gel-like texture which makes it easy to apply on the skin.

What is the function of the pump mechanism in this formula?

The pump mechanism facilitates easy and precise application of the gel. It helps to control the amount of product that comes out, reducing wastage and promoting efficient use.

How does this topical gel work?

When applied to the skin, the active ingredients in the gel are absorbed through the skin, providing targeted treatment to the affected area.

How should this topical gel be stored?

It's recommended to store the gel at room temperature, avoid freezing it, and keep it away from direct sunlight and heat. Always keep the container tightly closed when not in use.

What are the potential side effects of this formulation?

While side effects vary based on individual tolerance to the components, common side effects may include skin redness, irritation or rash at the application site. Always consult with your healthcare provider for specific medical advice.

Should this formulation be used for all types of pain?

This formulation is typically used for specific types of pain, like those associated with sprains, strains, or arthritis. However, it should not substitute for consultation with a healthcare provider.

Can I use this compounded formulation with other medications?

Always consult your healthcare provider before combining this, or any topical gel with other medications to prevent potential interactions or reactions.

Is it safe to use during pregnancy or breastfeeding?

Before using this formulation during pregnancy or while breastfeeding, please consult with your healthcare provider to discuss potential risks and benefits.

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Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.

No compounded medications are reviewed by the FDA for safety or efficacy.