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Baclofen 10%/Ketoprofen 10%/Lidocaine 5% Topical Gel

This formulation is a combination of Baclofen 10%, Ketoprofen 10%, and Lidocaine 5% in a topical gel. It is a semisolid formulation dispensed through a pump mechanism, which allows for easy and precise application on the skin. The gel-like consistency ensures targeted treatment or absorption of the active ingredients.

The Baclofen component is a muscle relaxant and antispastic agent, used to treat muscle symptoms caused by multiple sclerosis, including spasm, pain, and stiffness. Ketoprofen is a nonsteroidal anti-inflammatory drug (NSAID) that helps to reduce inflammation and pain in the body. Lidocaine is a local anesthetic that works by causing temporary numbness/loss of feeling in the skin and mucous membranes. This combination is often used to manage pain and inflammation associated with conditions such as arthritis, bursitis, and tendonitis.

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Topical Gel
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Formula Information

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This formulation combines Baclofen, Ketoprofen, and Lidocaine in a topical gel form. Baclofen is a muscle relaxant and antispasmodic agent, which helps to relieve muscle spasms, tightness, and pain. Ketoprofen is a nonsteroidal anti-inflammatory drug (NSAID) that reduces inflammation and pain in the body. Lidocaine is a local anesthetic that works by causing temporary numbness/loss of feeling in the skin and mucous membranes. This combination of medications is designed to provide targeted relief from pain and inflammation.

The gel is dispensed through a pump mechanism, which allows for easy and precise application. This is particularly beneficial for patients who may have difficulty applying traditional creams or ointments. The gel-like consistency also aids in the absorption of the active ingredients, providing faster and more effective relief.

This formulation is typically used to treat conditions such as muscle pain, arthritis, neuropathic pain, and other conditions that cause inflammation and discomfort. It works by reducing the body's production of substances that cause inflammation, pain, and fever. The addition of Lidocaine also provides immediate relief from pain by numbing the affected area.

It's important to note that this medication should only be used on the skin. Avoid contact with the eyes, mouth, and other mucous membranes. If the medication gets in these areas, rinse with plenty of water. Also, do not apply this medication to broken or irritated skin. If you have any allergies to the ingredients in this medication, or if you have a history of severe allergic reactions to NSAIDs, you should not use this medication.

As with any medication, it's important to use this formulation as directed by your healthcare provider. If you have any questions or concerns about this medication, or if you experience any side effects, please reach out to us at Bayview Pharmacy. We are a team of knowledgeable compounding pharmacists and we are here to help.

Drug Interactions

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This formulation combines Baclofen, Ketoprofen, and Lidocaine in a topical gel. Each of these active ingredients has its own potential drug interactions, which can be exacerbated when used in combination. It's important to inform your healthcare provider of all medications you are currently taking, including prescription drugs, over-the-counter medications, and herbal supplements.

Baclofen is a muscle relaxant and antispastic agent. It may interact with other central nervous system depressants such as alcohol, antihistamines, sedatives, tranquilizers, sleeping pills, prescription pain medications, narcotics, barbiturates, and certain antidepressants. These interactions could lead to increased sedation and even respiratory distress.

Ketoprofen is a nonsteroidal anti-inflammatory drug (NSAID). It may interact with anticoagulants like warfarin, increasing the risk of bleeding. It can also interact with other NSAIDs, corticosteroids, and alcohol, increasing the risk of gastrointestinal ulcers or bleeding. Ketoprofen may also interact with blood pressure medications, potentially reducing their effectiveness. Furthermore, it may interact with lithium and methotrexate, increasing the levels of these drugs in the body and potentially leading to toxicity.

Lidocaine is a local anesthetic. It may interact with other local anesthetics and certain antiarrhythmic drugs such as mexiletine and tocainide, leading to additive systemic toxicity. Lidocaine can also interact with certain antibiotics (such as erythromycin and itraconazole), anti-seizure drugs (such as phenytoin and phenobarbital), and other drugs that inhibit liver enzymes that break down lidocaine, potentially increasing the risk of lidocaine toxicity.

This formulation is designed to treat a variety of disease states. Baclofen can help relieve the symptoms of muscle spasms and spasticity associated with conditions like multiple sclerosis. Ketoprofen can reduce pain and inflammation associated with conditions like arthritis. Lidocaine can provide local anesthesia, relieving pain in a specific area of the body.

It's important to use this medication as directed by your healthcare provider. Apply the gel to the affected area in the amount and frequency prescribed. Avoid applying it to broken or irritated skin. Also, avoid getting the medication in your eyes, nose, or mouth. If this happens, rinse with water immediately.

If you have any questions about this formulation or its potential interactions, please don't hesitate to reach out to us. We're here to help ensure that your treatment is safe and effective.

How Does it Work

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The Baclofen 10%/Ketoprofen 10%/Lidocaine 5% Topical Gel is a unique formulation that combines the therapeutic benefits of three active ingredients: Baclofen, Ketoprofen, and Lidocaine. This formulation is designed to be applied topically, directly to the skin, where it can provide targeted treatment for a variety of disease states.

Baclofen is a muscle relaxant and antispastic agent. It works by inhibiting the transmission of reflexes at the spinal level, which can help to alleviate muscle spasms, pain, and stiffness. This makes it particularly useful in the management of conditions such as multiple sclerosis and spinal cord injuries.

Ketoprofen is a nonsteroidal anti-inflammatory drug (NSAID) that works by reducing hormones that cause inflammation and pain in the body. It is commonly used to relieve pain, swelling, and joint stiffness caused by arthritis. By including Ketoprofen in this formulation, it can provide localized relief from these symptoms without the systemic side effects that can occur with oral NSAIDs.

Lidocaine is a local anesthetic that works by blocking nerve signals in your body. When applied topically, it can provide rapid, localized pain relief by numbing the skin and underlying tissues. This makes it an effective treatment for conditions that cause pain on the skin's surface, such as shingles, or for procedures that involve the skin.

The gel formulation allows for easy and precise application of the medication directly to the affected area. The active ingredients are then absorbed through the skin, providing targeted treatment where it is needed most. The pump mechanism ensures that the correct dose is dispensed each time, reducing the risk of over or under-dosing.

This formulation is a powerful tool in the management of a variety of disease states. By combining the muscle-relaxing properties of Baclofen, the anti-inflammatory effects of Ketoprofen, and the pain-relieving action of Lidocaine, it can provide comprehensive symptom relief for patients suffering from conditions such as multiple sclerosis, arthritis, and shingles, among others.

If you have any questions about this formulation, or if you would like to know more about how it can benefit your patients, please don't hesitate to reach out to us at Bayview Pharmacy. Our team of knowledgeable compounding pharmacists is always here to help.

Other Uses

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This formulation, which contains Baclofen 10%, Ketoprofen 10%, and Lidocaine 5%, is primarily used for topical pain management. However, it may also have a number ofother uses. For example:

Baclofen is a muscle relaxant and antispastic agent that could possibly be effective in reducing symptoms related to muscle tension or spasticity conditions such as multiple sclerosis or spinal cord injuries. It may also be considered off-label for managing discomfort related to conditions like hiccups or Trigeminal Neuralgia.

Ketoprofen is a non-steroidal anti-inflammatory drug (NSAID) that may be used topically to alleviate conditions including arthritis, gout, or bursitis. It can also be employed to manage menstrual pain or other types of mild to moderate pain. Moreover, it could potentially be used off-label for its anti-inflammatory effects in conditions like sunburn or other minor burns.

Lidocaine, a local anesthetic and antiarrhythmic drug, can be used to numb the skin or surfaces of accessible mucous membranes in the body, potentially providing relief from itching, burning, and pain from skin inflammation. It is also beneficial in relieving discomfort from certain medical procedures. In some cases, it may also be used off-label for alleviating symptoms of certain types of neuropathic pain.

The combination of these three active ingredients may have potential benefit in managing a variety of other pain or discomfort states, such as neuropathic pain, post-op pain, post-herpetic neuralgia, fibromyalgia, or even sports injuries, in addition to muscle spasticity. The semisolid formulation enables a targeted treatment approach, enhancing the effectiveness of the active ingredients.

These potential alternate uses are dependent on the individual patient's condition and should always be used under the direction and supervision of a healthcare professional. It's important to understand that while these other uses are potential applications, they should not replace conventional treatments unless advised by a healthcare provider.

If you have any questions about this formulation or its potential uses, don't hesitate to reach out to us, the pharmacy team here at Bayview, for more information. Our knowledgeable compounding pharmacists are always available to provide advice and guidance.

Frequently Asked Questions

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What is the purpose of this baclofen/ketoprofen/lidocaine gel?

This is a compounded formulation designed to alleviate pain effectively. Baclofen, a muscle relaxer; ketoprofen, a nonsteroidal anti-inflammatory drug (NSAID); and lidocaine, a local anaesthetic, combined in a gel form can precisely target and treat pain when applied to the skin.

Why are these three medications compounded together?

Combining these medicines in a gel application allows for targeted treatment. Each medicine plays a different role in pain relief. The combination enhances the overall effect, providing a comprehensive pain management solution.

How do I apply this gel?

It's simple. Apply the gel to your skin over the affected area. The pump mechanism allows for comfortable and precise application, and as it's a gel, it absorbs quickly into the skin.

How often should I apply the gel?

Usage instructions usually depend on the specific condition being treated. Please follow your healthcare provider's advice on frequency and duration of application.

Can I use this topical gel over a large skin area?

Given that the gel contains potent medications, it's advisable to use it only on the recommended areas and not to apply it to large skin surfaces. Always follow the advice of your healthcare provider.

Are there any potential side effects?

As with any medication, potential side effects may occur, including skin irritation at the application site. If you experience any severe or persisting side effects, immediately consult your healthcare provider.

Is it safe to use this gel on broken or damaged skin?

No, it is not recommended to use this gel on broken or damaged skin. It's meant for application on intact skin surfaces to ensure the active ingredients are effectively delivered.

Can this gel be used with other medications?

Interaction with other medications depends on the specific medication in use. Always inform your healthcare provider about all medicines you are currently taking, including any over-the-counter (OTC) products.

What is the texture and feel of the gel after application?

After applying, the gel absorbs quickly, leaving a cool and soothing effect without any heavy residue or greasiness on the skin.

Is this gel available in pharmacies or is prescription required?

This gel is a compounded medication and typically requires a prescription. Always consult your healthcare professional for guidance.

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Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.

No compounded medications are reviewed by the FDA for safety or efficacy.