This formulation is a compounded transdermal gel containing Baclofen 1%, Gabapentin 3%, and Ketamine HCl 2%. It is a semisolid formulation that is dispensed through a pump mechanism, which allows for easy and precise application on the skin. The gel-like consistency of the formulation ensures that the active ingredients are absorbed effectively into the skin for targeted treatment.

Baclofen is a muscle relaxant and antispastic agent. It works by helping to relax the muscles and reduce muscle spasm, which can be beneficial in conditions such as multiple sclerosis and spinal cord injuries. Gabapentin is an anticonvulsant and nerve pain medication. It is often used to treat nerve pain conditions such as postherpetic neuralgia and diabetic neuropathy. Ketamine HCl is a potent analgesic that can provide significant pain relief in conditions such as complex regional pain syndrome (CRPS), fibromyalgia, and neuropathic pain.

The combination of these three active ingredients in a transdermal gel formulation allows for targeted treatment of the affected area. This can provide significant relief from pain and muscle spasm, improving the quality of life for patients suffering from these conditions. The transdermal route of administration also minimizes systemic side effects that can be associated with oral administration of these medications.

It is important to note that this is a compounded medication, meaning it is made specifically for you based on a prescription from your healthcare provider. It is not a commercially available product and should only be used under the supervision of a healthcare provider. As with any medication, it is important to use this product as directed by your healthcare provider and report any side effects or adverse reactions immediately.

If you have any questions about this formulation, or if you would like more information on how it can be used to treat your specific condition, please do not hesitate to reach out to us. Our team of knowledgeable compounding pharmacists at Bayview Pharmacy is always here to help.

This compounded formulation contains Baclofen, Gabapentin, and Ketamine HCl, all of which are medications that can interact with other drugs. It's important to inform your healthcare provider about all the medications you're currently taking, including over-the-counter drugs, vitamins, and herbal supplements, to avoid potential drug interactions.

Baclofen, a muscle relaxant and antispastic agent, can interact with other central nervous system depressants like alcohol, benzodiazepines, opioids, and antihistamines, potentially leading to increased sedation and respiratory depression. It can also interact with antihypertensive drugs, potentially enhancing their effects and causing hypotension.

Gabapentin, an anticonvulsant and nerve pain medication, can interact with antacids containing magnesium or aluminum, as they can reduce the absorption of gabapentin, decreasing its effectiveness. It can also interact with central nervous system depressants, leading to increased sedation and respiratory depression. Gabapentin's absorption can be increased if taken with a high fat meal, potentially leading to increased side effects.

Ketamine HCl, an anesthetic, can interact with other central nervous system depressants, potentially leading to increased sedation and respiratory depression. It can also interact with medications that affect serotonin levels in the body, such as selective serotonin reuptake inhibitors (SSRIs) and serotonin and norepinephrine reuptake inhibitors (SNRIs), potentially leading to a condition called serotonin syndrome. Symptoms of serotonin syndrome can range from shivering and diarrhea to muscle rigidity, fever, and seizures.

This formulation is designed to be applied topically, which can reduce the risk of systemic drug interactions. However, systemic absorption can still occur, especially if the medication is applied to broken or inflamed skin, or used over a large surface area. Therefore, it's still important to consider potential drug interactions.

This formulation is used to treat various disease states, including neuropathic pain, muscle spasticity, and complex regional pain syndrome. Baclofen works by relaxing the muscles and reducing muscle spasticity. Gabapentin works by reducing abnormal electrical activity in the brain, which can help reduce nerve pain. Ketamine HCl works by blocking certain receptors in the brain to provide pain relief and anesthesia.

If you have any questions about this formulation or potential drug interactions, please don't hesitate to reach out to us. We're here to help ensure that your medication is safe and effective for you.

The Baclofen 1%/Gabapentin 3%/Ketamine HCl 2% Transdermal Gel is a unique formulation that combines three active ingredients, each with its own mechanism of action, to provide targeted relief from certain disease states. This formulation is designed to be applied topically, directly to the skin, where it is absorbed into the body to exert its therapeutic effects.

Baclofen is a muscle relaxant and an antispastic agent. It works by restoring the normal transmission of nerve signals in certain parts of the brain. This helps to reduce muscle spasms, stiffness, and pain. In this formulation, baclofen is used to help manage symptoms associated with conditions like multiple sclerosis and spinal cord injury or disease.

Gabapentin is an anticonvulsant and nerve pain medication. It works by affecting the chemicals and nerves in the body that are involved in the cause of seizures and some types of pain. Gabapentin is particularly effective in treating nerve pain caused by shingles or herpes virus, diabetic neuropathy, and postherpetic neuralgia.

Ketamine HCl is a powerful anesthetic that works by blocking certain receptors in the brain, known as NMDA receptors. This helps to reduce pain signals and produce a numbing effect. In this formulation, ketamine HCl is used to help manage chronic pain conditions, including neuropathic pain and complex regional pain syndrome (CRPS).

The transdermal gel formulation allows for the active ingredients to be absorbed directly through the skin, providing targeted relief right where it's needed. The gel is dispensed through a pump mechanism, which makes it easy to apply and ensures a precise dose every time. This formulation is designed to minimize systemic absorption and reduce the risk of side effects commonly associated with oral administration of these medications.

It's important to note that this formulation should be used under the guidance of a healthcare provider, and the dosage will vary depending on the individual patient's condition and response to treatment. As with any medication, it's important to use this product as directed to ensure its safety and effectiveness.

If you have any questions about the Baclofen 1%/Gabapentin 3%/Ketamine HCl 2% Transdermal Gel, or if you would like more information about how it works, please don't hesitate to reach out to us at Bayview Pharmacy. Our team of knowledgeable compounding pharmacists is always here to help.

This transdermal gel formulation combining Baclofen, Gabapentin, and Ketamine HCl, primarily formulated to provide targeted pain relief, may also be beneficial for a variety of other medical conditions. Such alternative uses are largely due to the individual properties of each incorporated drug.

In addition to nerve pain, Baclofen in the formulation can be used off-label for conditions like muscle spasticity and stiffness associated with conditions such as multiple sclerosis, spinal cord injuries, or other spinal cord diseases. As a muscle relaxer and an antispastic agent, Baclofen may help to ease the symptoms of these conditions and increase overall patient comfort.

Adding to the versatility of this formulation, Gabapentin has been used off-label for managing insomnia, and anxiety disorders, in addition to its primary use in nerve pain and seizures. For patients struggling with these conditions, the inclusion of Gabapentin within the gel formulation may offer indirect benefits and provide a holistic approach to treatment.

Ketamine HCl in this formulation is known to provide relief from chronic pain through its interaction with NMDA receptors; however, it also has off-label use in treating refractory depression. Studies have found that Ketamine can have anti-depressant effects, making this gel formulation possibly beneficial for patients with co-existing chronic pain and depression.

However, it is important for patients and prescribers to know that these off-label uses have not been approved by the FDA and there may be limited research supporting their effectiveness in a transdermal gel form. It is vital to consult a healthcare provider before using the medication for these off-label uses. Moreover, the usage of the drug should be monitored closely for potential side effects or adverse reactions, as the combination of the drugs may pose a higher risk compared to individual usage.

Reach out to us if you have any questions regarding this or other formulations. As a team of compounding pharmacists, we are here to provide the knowledge you need to make informed decisions about your healthcare options.