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Formulas

Baclofen 1%/Cyclobenzaprine HCl 2%/Ketoprofen 20% Topical Gel

This formulation is a compounded topical gel containing Baclofen 1%, Cyclobenzaprine HCl 2%, and Ketoprofen 20%. It is a semisolid formulation dispensed through a pump mechanism, which allows for easy and precise application on the skin. The gel-like consistency ensures targeted treatment or absorption of the active ingredients.

The Baclofen component is a muscle relaxant and antispastic agent, while Cyclobenzaprine HCl is a muscle relaxant that works by blocking nerve impulses that are sent to your brain. Ketoprofen is a nonsteroidal anti-inflammatory drug (NSAID) that reduces hormones that cause inflammation and pain in the body. Together, these ingredients work to treat conditions such as muscle spasms, pain, and inflammation associated with various disease states.

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Topical Gel
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Formula Information

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This formulation combines Baclofen, Cyclobenzaprine HCl, and Ketoprofen in a topical gel, designed to be easily applied to the skin for targeted treatment. Baclofen is a muscle relaxant and antispastic agent, Cyclobenzaprine HCl is a muscle relaxant, and Ketoprofen is a nonsteroidal anti-inflammatory drug (NSAID). Together, these active ingredients work synergistically to alleviate pain, reduce inflammation, and relax muscles.

Baclofen 1%/Cyclobenzaprine HCl 2%/Ketoprofen 20% Topical Gel is a semisolid formulation dispensed through a pump mechanism. This design allows for easy and precise application, ensuring that the medication is delivered directly to the affected area. The gel-like consistency aids in absorption of the active ingredients, providing rapid relief from symptoms.

This formulation is particularly effective in treating various disease states associated with pain and inflammation. These include conditions like arthritis, muscle sprains and strains, back pain, and other musculoskeletal disorders. The combination of muscle relaxants and an NSAID provides a comprehensive approach to pain management, addressing both the symptoms and the underlying causes of discomfort.

For patients, it's important to note that this medication should be applied as directed by a healthcare provider. Avoid contact with eyes, open wounds, or damaged skin. If any adverse reactions occur, such as skin irritation or allergic reactions, discontinue use and consult your healthcare provider immediately.

For prescribers, this formulation offers a targeted, non-systemic approach to pain management. It can be a suitable option for patients who cannot tolerate oral medications or for those who require localized treatment. As with all medications, monitor your patients closely for any potential side effects or adverse reactions.

If you have any questions about this formulation or its use, please don't hesitate to reach out to us at Bayview Pharmacy. Our team of knowledgeable compounding pharmacists is always here to assist you.

Drug Interactions

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This formulation combines Baclofen, Cyclobenzaprine HCl, and Ketoprofen in a topical gel. Each of these active ingredients has its own potential for drug interactions, which can be amplified when used in combination. It's important to consider these interactions when prescribing or using this medication.

Baclofen is a muscle relaxant and antispastic agent. It may interact with other central nervous system depressants, including alcohol, antihistamines, sedatives, and narcotics, potentially leading to increased sedation or respiratory depression. Concurrent use with antihypertensive drugs may result in additive hypotensive effects.

Cyclobenzaprine HCl is also a muscle relaxant. It can interact with monoamine oxidase inhibitors (MAOIs), causing serious, potentially fatal reactions. It may also interact with other central nervous system depressants, tricyclic antidepressants, and serotonergic drugs, potentially leading to serotonin syndrome, a potentially life-threatening condition.

Ketoprofen is a nonsteroidal anti-inflammatory drug (NSAID). It may interact with anticoagulants, increasing the risk of bleeding. It can also interact with other NSAIDs, corticosteroids, and alcohol, increasing the risk of gastrointestinal ulcers or bleeding. Concurrent use with antihypertensive drugs or diuretics may decrease their effectiveness. Ketoprofen may also interact with lithium or methotrexate, increasing their levels in the body.

This formulation is intended for topical use, which may reduce the risk of systemic drug interactions. However, significant systemic absorption can occur, especially when applied to large areas of the body or used over a long period of time. Therefore, the potential for drug interactions should not be overlooked.

This formulation is used to treat various disease states, including muscle spasms, pain, and inflammation associated with conditions such as multiple sclerosis, fibromyalgia, and arthritis. By combining three active ingredients with different mechanisms of action, it provides a multi-modal approach to pain management, potentially improving efficacy while minimizing side effects.

Patients should inform their healthcare provider of all medications they are currently taking, including prescription drugs, over-the-counter medications, and dietary supplements, to avoid potential drug interactions. They should also inform their healthcare provider if they have any medical conditions, as these may affect the safety and effectiveness of this formulation.

If you have any questions about this formulation or its potential drug interactions, please don't hesitate to reach out to us. We are here to help ensure the safe and effective use of this medication.

How Does it Work

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This formulation is a compounded medication that combines Baclofen, Cyclobenzaprine HCl, and Ketoprofen in a topical gel. Each of these active ingredients plays a unique role in managing pain and inflammation, and their combined effect can provide significant relief for a variety of disease states.

Baclofen is a muscle relaxant and antispastic agent. It works by inhibiting the transmission of reflexes at the spinal level, which can help to reduce muscle spasms, pain, and stiffness. This makes it particularly useful in conditions where spasticity is a problem, such as multiple sclerosis or spinal cord injuries.

Cyclobenzaprine HCl is another muscle relaxant. It acts centrally within the brain stem to reduce muscle tone and decrease the frequency and severity of muscle spasms. It's often used to treat muscle spasms associated with acute musculoskeletal conditions.

Ketoprofen is a nonsteroidal anti-inflammatory drug (NSAID). It works by reducing the production of prostaglandins, chemicals that cause inflammation, pain, and fever in the body. Ketoprofen is used to relieve pain, reduce inflammation, and lower fever.

When these three medications are combined in a topical gel, they can provide targeted relief right where it's needed. The gel is applied directly to the skin over the affected area, allowing the active ingredients to be absorbed through the skin and into the underlying tissues. This can provide more direct relief than oral medications, which must be absorbed through the digestive system and distributed throughout the entire body.

This formulation is particularly useful for conditions that cause muscle spasms and inflammation, such as fibromyalgia, arthritis, and sports injuries. It can also be used to manage pain and inflammation after surgery. As with any medication, it's important to use this formulation as directed by your healthcare provider, and to discuss any potential side effects or interactions with other medications you're taking.

If you have any questions about this formulation, or if you'd like to know more about how it can be used to manage your specific condition, please don't hesitate to reach out to us. Our team of knowledgeable compounding pharmacists is always here to help.

Other Uses

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This proprietary blend of Baclofen 1%/Cyclobenzaprine HCl 2%/Ketoprofen 20% in a Topical Gel form is primarily used to manage pain and muscle spasms associated with conditions like fibromyalgia, multiple sclerosis, and musculoskeletal conditions. However, there are other uses for this formulation that both physicians and patients might need to consider.

First, the combination of these medications may have a potential role in treating neuropathic pain, a condition often associated with nerve damage or a malfunctioning nervous system. This is largely accredited to the analgesic property of Ketoprofen and the muscle relaxant effects of Baclofen and Cyclobenzaprine HCl, which may alleviate the symptoms associated with this type of pain.

Furthermore, this topical pain reliever may also be utilized in sports medicine for the treatment of acute injuries like sprains, strains, and contusions. Its anti-inflammatory and pain-relieving properties can mitigate swelling, inflammation, and discomfort associated with such injuries, facilitating faster recovery.

Interestingly, mounting evidence suggests the possible utility of this medication in managing pain associated with conditions like arthritis and bursitis. The potent anti-inflammatory activity of Ketoprofen and the muscle relaxant properties of Baclofen and Cyclobenzaprine HCl could potentially help in reducing pain, inflammation, and improving mobility in afflicted joints.

This compounding prescription is designed for topical application, which translates to a lower risk of systemic adverse effects compared to oral dosages of the same medication. However, potential for local side effects, allergies, and drug interactions should still be evaluated by your healthcare provider before use. As always, it should be applied as directed by your prescriber, and it is essential not to exceed the recommended dosage.

If you have any questions about this formulation of Baclofen 1%/Cyclobenzaprine HCl 2%/Ketoprofen 20% Topical Gel or its potential uses, don't hesitate to reach out to us at Bayview Pharmacy. We’re here to guide you through your treatment journey and provide you with the most personalized pharmaceutical care.

Frequently Asked Questions

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What is the Baclofen 1%/Cyclobenzaprine HCl 2%/Ketoprofen 20% Topical Gel?

This is a compounded formulation of active ingredients Baclofen (1%), Cyclobenzaprine HCl (2%) and Ketoprofen (20%). It is a semi-solid formulation dispensed through a pump mechanism, allowing for easy and precise application directly on the skin for targeted treatment.

What is the purpose of this compounded gel?

Each ingredient in the gel serves a separate purpose. Baclofen is a muscle relaxer and an antispastic agent. Cyclobenzaprine HCl provides relief from muscle spasms, while Ketoprofen is a nonsteroidal anti-inflammatory drug (NSAID) that reduces inflammation and pain in the body.

How do you use this topical formulation?

You should apply this gel topically to the targeted area on your skin as directed by your physician. Use the pump mechanism on the container to obtain the medication accurately and then spread over the skin evenly.

Can this gel be used on any area of the body?

The gel should only be used on the area of the body as advised by your doctor. Avoid applying the gel on broken skin, wounds, or near sensitive areas like your eyes, and mouth.

Can I use more gel to increase its effectiveness?

No, using more gel than recommended will not increase its effectiveness and can potentially lead to serious side effects. Always use the medication as directed by your healthcare provider.

What do I do if I develop an allergic reaction to the gel?

If you experience symptoms such as rash, itching, severe dizziness or difficulty breathing, you might have an allergic reaction to the topical gel. Seek immediate medical attention in such cases.

Can I use this formulation while pregnant or breastfeeding?

This medication should only be used during pregnancy or breastfeeding if absolutely necessary and prescribed by your healthcare provider. Always consult with your doctor before using this formulation if you are pregnant or breastfeeding.

How should I store this medication?

Store this medication at room temperature, away from light and moisture. Keep the container tightly closed when not in use, and out of reach of children.

What to do in case of missed dose?

If you miss applying the medication, do it as soon as you remember. However, if it's almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose to catch up.

What happens if I mistakenly ingest the gel?

This formulation is designated solely for topical applications. If the product is accidentally ingested, contact a healthcare provider or poison control immediately.

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Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.

No compounded medications are reviewed by the FDA for safety or efficacy.