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Formulas

Azithromycin Dihydrate 1.0% Ophthalmic Liquid

The Azithromycin Dihydrate 1.0% Ophthalmic Liquid is a specialized formulation prepared by our team of compounding pharmacists at Bayview Pharmacy. This ophthalmic solution is specifically designed for the treatment of various eye infections caused by bacteria, including conjunctivitis and keratitis.

As an antibiotic, Azithromycin Dihydrate works by stopping the growth of bacteria, thereby helping to eliminate the infection. The 1.0% concentration ensures an effective dose is delivered directly to the eye, providing relief from symptoms and promoting faster healing.

It is important to note that this medication is only for use in the eyes. It should not be ingested or applied to other areas of the body. As with all medications, it should be used as directed by a healthcare professional.

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Ophthalmic Liquid
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Formula Information

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Azithromycin Dihyrate 1.0% Ophthalmic Liquid is a specialized formulation designed to treat a variety of ocular infections. Azithromycin is a broad-spectrum antibiotic that belongs to the macrolide group. It works by inhibiting bacterial protein synthesis, effectively stopping the growth and multiplication of bacteria. This makes it a potent weapon against bacterial infections in the eye.

This formulation is typically used to treat bacterial conjunctivitis and blepharitis, as well as other bacterial infections of the eye. It can also be used prophylactically to prevent infections after eye surgery. The 1.0% concentration provides a potent dose of the antibiotic, ensuring effective treatment of the infection.

Patients using Azithromycin Dihyrate 1.0% Ophthalmic Liquid should apply it as directed by their healthcare provider, typically one to two drops in the affected eye(s) twice daily. It's important to continue using the medication for the full course of treatment, even if symptoms improve before the infection is completely cleared. Stopping the medication too early may allow bacteria to continue to grow, which may result in a return of the infection.

Common side effects may include eye irritation, burning, stinging, or redness. However, these side effects are generally mild and temporary. If they persist or worsen, patients should contact their healthcare provider. Serious side effects are rare, but patients should seek immediate medical attention if they experience severe eye pain, vision changes, or signs of a new infection.

Prescribers should be aware that Azithromycin Dihyrate 1.0% Ophthalmic Liquid may interact with other medications, particularly other eye drops. Therefore, it's important to inform patients to wait at least 5 minutes between applying this medication and any other eye drops. Additionally, contact lenses should not be worn while using this medication as it may discolor the lenses.

At Bayview Pharmacy, we are committed to providing high-quality, personalized care. If you have any questions about Azithromycin Dihyrate 1.0% Ophthalmic Liquid or any other medication, please don't hesitate to reach out to us. Our team of knowledgeable compounding pharmacists is always here to help.

Drug Interactions

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Azithromycin Dihydrate 1.0% Ophthalmic Liquid is an antibiotic medication used to treat bacterial infections of the eye, such as conjunctivitis and blepharitis. It works by inhibiting the growth of bacteria, thereby helping to eliminate the infection and alleviate symptoms such as redness, swelling, and itching.

While Azithromycin Dihydrate is generally well-tolerated, it can interact with certain other medications, potentially affecting their efficacy or increasing the risk of side effects. It is important to inform your healthcare provider of all medications you are currently taking, including prescription drugs, over-the-counter medications, and dietary supplements.

One of the most significant drug interactions involves antacids containing aluminum or magnesium, such as Maalox, Mylanta, or Rolaids. These antacids can bind to azithromycin, preventing it from being fully absorbed into the body. To avoid this interaction, it is recommended to take azithromycin at least 1 hour before or 2 hours after taking an antacid.

Other medications that can interact with azithromycin include blood thinners (such as warfarin), cyclosporine, digoxin, and certain HIV medications. These interactions can lead to increased levels of these drugs in the body, potentially resulting in toxicity. If you are taking any of these medications, your healthcare provider may need to adjust your dose or monitor you more closely for side effects.

It's also important to note that azithromycin can prolong the QT interval, a measure of the time it takes for the heart muscle to recharge between beats. This can potentially lead to a serious, life-threatening heart rhythm disorder, especially in individuals with existing heart conditions or those taking other medications that prolong the QT interval. Therefore, azithromycin should be used with caution in these individuals.

Lastly, while azithromycin is generally safe to use during pregnancy, it should be used only when clearly needed, as the effects on the developing fetus are not fully known. If you are pregnant or planning to become pregnant, discuss the potential risks and benefits with your healthcare provider.

If you have any questions about the potential interactions of Azithromycin Dihydrate 1.0% Ophthalmic Liquid, please don't hesitate to reach out to us. We are here to provide you with the most accurate and up-to-date information to ensure your safety and the effectiveness of your treatment.

How Does it Work

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Azithromycin Dihydrate 1.0% Ophthalmic Liquid is a specialized formulation designed to treat a variety of eye infections. Azithromycin is a broad-spectrum antibiotic that belongs to the macrolide class. It works by inhibiting the growth of bacteria by interfering with their protein synthesis.

When applied as an ophthalmic solution, Azithromycin Dihydrate acts directly on the site of infection. It penetrates the bacterial cell by diffusing through the cell membrane. Once inside, it binds to the 50S subunit of the bacterial ribosome, thereby inhibiting the translocation of peptides. This process disrupts protein synthesis and prevents the bacteria from growing and multiplying, which eventually leads to their death.

This formulation is particularly effective against a wide range of bacteria, including Staphylococcus aureus, Streptococcus pneumoniae, Haemophilus influenzae, and Moraxella catarrhalis, among others. These bacteria are commonly responsible for conditions such as bacterial conjunctivitis and blepharitis.

As an ophthalmic solution, Azithromycin Dihydrate 1.0% provides targeted treatment with minimal systemic absorption, reducing the risk of potential side effects. It is typically well-tolerated, with most patients experiencing only mild and transient side effects such as eye irritation or discomfort.

It's important to note that Azithromycin Dihydrate 1.0% Ophthalmic Liquid should only be used under the guidance of a healthcare professional. It is not effective against viral or fungal eye infections, and inappropriate use can contribute to antibiotic resistance.

For optimal results, patients should follow the prescribed dosage and complete the full course of treatment, even if symptoms improve before the medication is finished. This ensures that all bacteria are eliminated, preventing a potential recurrence of the infection.

If you have any questions about Azithromycin Dihydrate 1.0% Ophthalmic Liquid, or if you would like more information about its use and potential side effects, please don't hesitate to reach out to us at Bayview Pharmacy. Our team of knowledgeable compounding pharmacists is always here to help.

Other Uses

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At Bayview Pharmacy, our team of experienced compounding pharmacists take pride in their knowledge of the potential uses of our formulations beyond their typical applications. With that in mind, we would like to discuss Azithromycin Dihydrate 1.0% Ophthalmic Liquid, which is commonly used as an ocular antibiotic to treat bacterial infections in the eye such as conjunctivitis and keratitis. However, this versatile formulation possesses potential for other therapeutic applications.

Azithromycin, a broad-spectrum antibiotic, has been found to be effective in treating skin infections when applied topically. As such, in some cases, Azithromycin Dihydrate Ophthalmic Liquid might be used off-label by dermatologists to control skin conditions caused by bacterial infections, such as acne vulgaris, rosacea, or folliculitis. However, such an application should always be under the guidance of a healthcare provider who can evaluate your unique circumstances and condition.

Further, Azithromycin is also known to have anti-inflammatory properties. Preliminary studies suggest that the ophthalmic solution may alleviate symptoms of inflammatory ocular conditions like blepharitis and post-operative inflammation in patients who have undergone ocular surgeries. However, more research is needed to conclusively establish these benefits, and usage should be under the supervision of an experienced clinician.

Lastly, while less common, Azithromycin Dihydrate Ophthalmic Liquid has been used in some cases to treat ear infections due to its bacteriostatic effects against common pathogens. Here, too, a healthcare provider would determine whether the potential benefits outweigh the risks and monitor the patient carefully for any adverse reactions.

Keep in mind that this information is intended for educational purposes only and should not be used as a basis for self-medication or to replace professional medical advice. We always recommend discussing treatment options and their potential off-label uses with your healthcare provider. As always, if there are any additional questions you may have, please feel free to reach out to us here at Bayview Pharmacy. We are more than happy to further assist you.

Frequently Asked Questions

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What is Azithromycin Dihydrate 1.0% Ophthalmic Liquid?

Azithromycin Dihydrate 1.0% Ophthalmic Liquid is a compounded formulation medication used for treating bacterial infections in the eyes.

What does "compounded formulation" mean?

A compounded formulation is a preparation that is created by a pharmacist to meet the unique needs of an individual patient when commercially available drugs do not meet those needs.

How is Azithromycin Dihydrate 1.0% Ophthalmic Liquid used?

It is typically applied directly into the infected eye or eyes as directed by your healthcare professional.

Who should use this medication?

It is intended for patients diagnosed with specific bacterial eye infections, based on the prescription of a healthcare professional.

Are there any side effects?

Potential side effects include minor eye discomfort and temporary vision changes. If any of these side effects worsen or persist, contact your healthcare professional immediately.

What precautions should I take while using this medication?

Always wash your hands thoroughly before applying this ophthalmic liquid. Do not touch the tip of the dropper or let it touch your eyes or any other surfaces.

Can I wear contacts while taking Azithromycin Dihyrate 1.0% Ophthalmic Liquid?

Typically, it is not recommended to wear contact lenses until the infection completely subsides. Consult with your healthcare professional for more personalized advice.

Can I use other eye medications while using this formulation?

Always consult with your healthcare professional before starting any new medication, including eye medications, while using this ophthalmic liquid.

How should this medication be stored?

This medication should be stored in a cool, dry location. Keep the bottle tightly closed when not in use, and do not freeze the liquid.

What should I do if I miss a dose?

If you miss a dose, apply it as soon as you remember. If it is nearly time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to catch up.

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Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.

No compounded medications are reviewed by the FDA for safety or efficacy.