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Azelaic Acid 6%/Hydrocortisone 1%/Hydroquinone 6%/Kojic acid 2%/Retinoic acid 0.025% Topical Gel

This formulation is a semisolid topical gel containing Azelaic Acid 6%, Hydrocortisone 1%, Hydroquinone 6%, Kojic acid 2%, and Retinoic acid 0.025%. It is dispensed through a pump mechanism, which allows for easy and precise application on the skin. The active ingredients in this formulation work together to target and treat various skin conditions.

Azelaic Acid and Kojic Acid are known for their skin-lightening properties and are effective in treating hyperpigmentation and melasma. Hydroquinone is another potent skin-lightening agent that helps to reduce the appearance of dark spots and discoloration. Hydrocortisone is a corticosteroid that reduces inflammation and redness, making it beneficial for conditions like dermatitis and eczema. Retinoic Acid, a form of Vitamin A, promotes skin cell turnover and is commonly used in the treatment of acne and signs of aging.

Together, these ingredients provide a comprehensive treatment for a range of skin conditions, delivering targeted treatment and absorption in a convenient gel-like consistency.

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Topical Gel
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Formula Information

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This formulation is a unique blend of Azelaic Acid 6%, Hydrocortisone 1%, Hydroquinone 6%, Kojic acid 2%, and Retinoic acid 0.025% in a topical gel form. It is designed to be dispensed through a pump mechanism, which allows for easy and precise application on the skin. The gel-like consistency ensures that the active ingredients are absorbed effectively for targeted treatment.

Azelaic Acid is a naturally occurring acid that helps the skin to renew itself more quickly and therefore reduces pimple and blackhead formation. It also helps to kill the bacteria that cause acne and rosacea. Hydrocortisone is a corticosteroid that reduces swelling, itching, and redness. This can be particularly beneficial for conditions like eczema, psoriasis, and rash.

Hydroquinone is a skin-bleaching agent that works by decreasing the number of melanocytes present. Melanocytes make melanin, which produce the color of the skin. By decreasing the number of melanocytes, dark spots on the skin due to sun damage, age, or hormonal changes are lightened. Kojic acid is a chelation agent produced by several species of fungi which inhibits and prevents the formation of pigment in skin. This makes it effective for reducing hyperpigmentation and age spots.

Retinoic acid, also known as Tretinoin, is a form of vitamin A that helps the skin renew itself. It is commonly used to treat acne and reduce the appearance of fine wrinkles and mottled skin discoloration, and to make rough facial skin feel smoother.

This formulation is a comprehensive solution for a variety of skin conditions, including acne, rosacea, eczema, psoriasis, hyperpigmentation, age spots, and wrinkles. It is important to use this medication under the guidance of a healthcare provider, as some of the ingredients can cause side effects such as skin irritation and sensitivity to sunlight. Always apply the medication as directed, and avoid contact with the eyes, mouth, or open wounds.

If you have any questions about this formulation, please do not hesitate to reach out to us at Bayview Pharmacy. Our team of knowledgeable compounding pharmacists is always here to help.

Drug Interactions

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This topical gel formulation contains a combination of Azelaic Acid, Hydrocortisone, Hydroquinone, Kojic acid, and Retinoic acid. Each of these active ingredients has its own unique properties and potential interactions with other medications.

Azelaic Acid is a dicarboxylic acid that helps the skin to renew itself more quickly and therefore reduces pimple and blackhead formation. It also helps to kill the bacteria that can lead to acne and rosacea. It is generally well-tolerated, but it may interact with other skin products that cause dryness or irritation, including harsh soaps, shampoos, or skin cleansers, hair coloring or permanent chemicals, hair removers or waxes, or skin products with alcohol, spices, astringents, or lime.

Hydrocortisone is a corticosteroid that reduces swelling, itching, and redness. It may interact with other corticosteroids taken by mouth or applied to the skin, leading to increased effects and potential side effects. It may also interact with certain medications that weaken the immune system, including cyclosporine and tacrolimus.

Hydroquinone is a skin-bleaching agent that is used to lighten areas of darkened skin such as freckles, age spots, chloasma, and melasma. It may interact with peroxide (including benzoyl peroxide), resorcinol, salicylic acid, or sulfur-containing products, which can cause temporary staining of the skin.

Kojic acid is a chelation agent produced by several species of fungi, especially Aspergillus oryzae, which has the Japanese common name koji. It is used to lighten skin and treat melasma. It may interact with other skin products that cause dryness or irritation.

Retinoic acid, also known as tretinoin, is a medication used for the treatment of acne and acute promyelocytic leukemia. It may interact with other skin products that cause dryness or irritation, including medicated or abrasive soaps and cleansers, products containing alcohol/astringents/spices, products containing sulfur, resorcinol, or salicylic acid, products containing alpha hydroxy acid, products containing glycolic acid, soaps and cosmetics with a strong drying effect, and other drugs that may increase your sensitivity to sunlight (including fluoroquinolones, thiazides, tetracyclines, sulfa drugs, and phenothiazines).

Patients should inform their healthcare provider of all the products they use, including prescription drugs, nonprescription drugs, and herbal products, before starting treatment with this formulation. Also, patients should avoid using other skin products that can cause irritation, such as harsh soaps, shampoos, or skin cleansers, hair coloring or permanent chemicals, hair removers or waxes, or skin products with alcohol, spices, astringents, or lime.

If you have any questions about the potential interactions of this formulation, please reach out to us at Bayview Pharmacy. We are a team of knowledgeable compounding pharmacists who are here to help.

How Does it Work

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This topical gel formulation combines the active ingredients Azelaic Acid, Hydrocortisone, Hydroquinone, Kojic Acid, and Retinoic Acid, each contributing to the overall therapeutic effect of the product. The gel is designed to be easily applied to the skin, where it is absorbed and begins to work on the targeted treatment area.

Azelaic Acid, at a concentration of 6%, works by reducing the growth of skin bacteria that can block pores, and by reducing inflammation. This can help to treat acne and rosacea, and can also help to lighten the skin in areas where hyperpigmentation has occurred.

Hydrocortisone, at a concentration of 1%, is a corticosteroid that works by reducing inflammation and swelling. This can help to soothe irritated skin and reduce redness, making it useful in treating conditions such as eczema and dermatitis.

Hydroquinone, at a concentration of 6%, is a skin-lightening agent. It works by reducing the production of melanin, the pigment that gives skin its color. This can help to lighten areas of the skin that have become darkened due to conditions such as melasma or post-inflammatory hyperpigmentation.

Kojic Acid, at a concentration of 2%, is another skin-lightening agent. It works in a similar way to Hydroquinone, by inhibiting the production of melanin. It can also help to treat melasma and post-inflammatory hyperpigmentation, and can be used in combination with Hydroquinone for a more potent effect.

Retinoic Acid, at a concentration of 0.025%, is a form of Vitamin A that can help to promote skin cell turnover. This can help to reduce the appearance of fine lines and wrinkles, and can also help to treat acne by preventing the formation of new comedones (blocked pores).

This formulation is dispensed through a pump mechanism, which allows for easy and precise application of the product. The gel-like consistency helps to ensure that the active ingredients are absorbed into the skin where they can begin to work.

If you have any questions about this formulation, or if you would like more information on how it can be used to treat specific skin conditions, please don't hesitate to reach out to us at Bayview Pharmacy. Our team of knowledgeable compounding pharmacists is always here to help.

Other Uses

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This topical gel formulation, which contains Azelaic Acid, Hydrocortisone, Hydroquinone, Kojic Acid, and Retinoic Acid, not only helps in treating various skin conditions like hyperpigmentation, acne, and melasma, but it also has other potential uses. This formulation could prove beneficial for post-inflammatory hyperpigmentation, often resulting from acne scars or injury. The Hydroquinone and Kojic Acid combination works to lighten the skin darker than normal by inhibiting the production of melanin, providing relief to those with hyperpigmentation.

Besides lightening hyperpigmentation, Azelaic Acid can help reduce the redness, inflammation, and swelling caused by rosacea. Hydrocortisone, on the other hand, has anti-inflammatory properties that might be useful for temporary relief of itching and discomfort from skins affected by minor skin irritations, allergic reactions, or insect bites.

Moreover, the Retinoic Acid present in the formulation can expedite the turnover of skin cells, therefore it could be used for anti-aging treatments. This aids in the reduction of fine lines and wrinkles, giving the skin a youthful appearance. It could also be used to manage the appearance of stretch marks by promoting collagen production to fill and repair the stretch mark from within.

Another possible use of this formulation could be in the treatment of solar keratosis, a condition often caused by excessive sunlight exposure. The Azelaic Acid and Retinoic Acid together help in decreasing the thickness of the hardened, scaly patches of skin that hallmark this condition.

However, it’s important to remember that this formulation may cause photosensitivity due to some of its constituents. Extra caution should be taken during sunlight or UV exposure, utilize protective measures such as sunscreen or protective clothing. Additionally, it is important to perform a patch test before fully applying any new product, as there may be adverse effects for individuals with sensitive skin or allergies to any of the composition. Always follow healthcare provider advice for dilation or abnormal uses.

If you have further questions about this formulation and its uses, feel free to reach out to us at Bayview Pharmacy. Our knowledgeable team of compounding pharmacists is enthusiastic to answer queries and aid in providing individualized patient care.

Frequently Asked Questions

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What is the compound formulation of Azelaic Acid 6%/Hydrocortisone 1%/Hydroquinone 6%/Kojic acid 2%/Retinoic acid 0.025% Topical Gel?

This is a custom mixed medication that combines Azelaic Acid, Hydrocortisone, Hydroquinone, Kojic Acid, and Retinoic Acid in specific concentrations in a gel form for topical application. All these ingredients have beneficial properties for skincare.

What does the gel-like consistency offer?

The gel-like consistency allows for easy and precise application on the skin. It ensures that the active ingredients are targeted and absorbed well by the skin. It is smooth, light, and usually non-greasy compared to creams and lotions.

How is this compounded formulation dispensed?

This compounded formulation is dispensed through a pump mechanism. This mechanism allows for easy dose and application, ensuring you get the right amount of product every time.

What is the benefit of each active ingredient in the compounded formulation?

Azelaic Acid has anti-inflammatory, anti-oxidant and anti-bacterial properties which can help with acne. Hydrocortisone is used to decrease swelling and itching. Hydroquinone helps to lighten the skin. Kojic Acid also lightens skin and decreases the amount of a pigment called melanin in the skin while Retinoic Acid assists with skin renewal.

Can I use this formulation for any skin type or skin condition?

Prescription skincare products like this compounded formulation are tailored to an individual's unique skin condition and skin type. It is important to consult with your healthcare provider before starting any new medication, including this compounded formulation.

How should I use this compounded formulation?

Always use this formulation as directed by your prescriber. Remember, a thin layer is usually enough for the active ingredients to work effectively.

Are there any side effects related to this compounded formulation?

All medications can have potential side effects. Common side effects with these active ingredients can include mild burning, stinging, or itching of treated skin. Severe side effects aren't common, but they can occur. Always contact your prescriber if you notice any unusual symptoms.

Can I apply other skincare products while using this formulation?

Check with your healthcare provider before combining this formulation with other skincare products. Many skincare products may react negatively with these active ingredients, which may interfere with their effectiveness or increase side effects.

Should I expect immediate results from this compounded formulation?

Results can vary from person to person based on multiple factors and usually depend on the skin condition being treated. It's important to use the product consistently and as directed to see best results. Always consult your healthcare provider with questions about your treatment plan.

Is this compounded formulation safe to use during pregnancy?

Some active ingredients in this formulation, such as Retinoic Acid and Hydroquinone, may not be safe to use during pregnancy. Always consult with your healthcare provider before starting any skincare regimen, especially if you are pregnant or breastfeeding.

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Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.

No compounded medications are reviewed by the FDA for safety or efficacy.