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Formulas

Azelaic Acid 5%/Clindamycin 1%/Niacinamide 4% Topical Gel

This formulation is a semisolid, gel-like compound of Azelaic Acid 5%, Clindamycin 1%, and Niacinamide 4%. It is dispensed through a pump mechanism, allowing for easy and precise application on the skin. The active ingredients in this formulation work together to target and treat various skin conditions.

Azelaic Acid is a dicarboxylic acid that helps to reduce inflammation and kill bacteria that cause acne. Clindamycin is an antibiotic that prevents bacteria from growing on the skin. Niacinamide, also known as Vitamin B3, has anti-inflammatory properties that can help ease redness from eczema, acne, and other inflammatory skin conditions.

This formulation is particularly effective in treating acne vulgaris, rosacea, and hyperpigmentation. It can also be used to improve skin texture and reduce the appearance of wrinkles.

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Topical Gel
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Formula Information

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This formulation combines Azelaic Acid 5%, Clindamycin 1%, and Niacinamide 4% in a topical gel. Azelaic Acid is a dicarboxylic acid that helps the skin to renew itself more quickly and therefore reduces pimple and blackhead formation. It also helps to kill the bacteria that can lead to acne and rosacea and it can decrease the production of keratin, a natural substance that can lead to the development of acne.

Clindamycin is an antibiotic that prevents bacteria from growing on the skin. It works by slowing or stopping the growth of bacteria that cause acne and by decreasing swelling. Niacinamide, also known as vitamin B3, has anti-inflammatory properties that can help ease redness from eczema, acne, and other inflammatory skin conditions. It also helps build cells in the skin while also protecting them from environmental stresses, such as sunlight, pollution, and toxins.

This formulation is dispensed through a pump mechanism, which allows for easy and precise application on the skin. The gel-like consistency ensures that the active ingredients are absorbed effectively into the skin for targeted treatment. This formulation is typically used to treat acne, rosacea, and other inflammatory skin conditions.

It is important to use this medication exactly as prescribed by your doctor. The amount of medicine that you take depends on the strength of the medicine and the condition of the patient. Do not use more of it, do not use it more often, and do not use it for a longer time than your doctor ordered. Also, this medication should only be used on the skin. Do not swallow it and avoid getting it in your eyes, nose, or mouth.

As with any medication, there may be side effects. These can include dryness, redness, peeling, or itching of the skin. If these side effects persist or worsen, contact your doctor or pharmacist promptly. Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects.

If you have any questions about this formulation, please do not hesitate to reach out to us at Bayview Pharmacy. Our team of knowledgeable compounding pharmacists is here to assist you.

Drug Interactions

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This formulation combines Azelaic Acid, Clindamycin, and Niacinamide, each with its own unique therapeutic properties. Azelaic Acid is a dicarboxylic acid that helps the skin to renew itself more quickly and therefore reduces pimple and blackhead formation. It also helps to kill the bacteria that can cause acne and rosacea. Clindamycin is an antibiotic that prevents bacteria from growing on the skin. Niacinamide, also known as vitamin B3, has anti-inflammatory properties that can help ease redness from eczema, acne, and other inflammatory skin conditions.

While this formulation is generally considered safe, it's important to be aware of potential drug interactions. Clindamycin, one of the active ingredients, can interact with certain other medications. For example, it may increase the effects of neuromuscular blocking agents and other anesthetics. If you're currently taking any medications, particularly those for muscle conditions or for anesthesia during surgery, it's important to inform your healthcare provider.

Azelaic Acid and Niacinamide are generally considered safe with few drug interactions. However, they can cause skin irritation, especially when used with other topical medications. If you're using other topical treatments, particularly those containing salicylic acid or retinoids, you should discuss this with your healthcare provider to avoid potential skin irritation.

It's also important to note that while this formulation can help manage symptoms of acne and rosacea, it's not a cure. Continued use may be necessary to maintain benefits. Also, this medication should only be used on the skin. Avoid contact with the eyes, mouth, or other mucous membranes. If the medication does get in these areas, rinse with plenty of water.

As with any medication, it's important to use this formulation as directed by your healthcare provider. If you have any questions or concerns about potential drug interactions or how to use this medication, don't hesitate to reach out to us at Bayview Pharmacy. We're here to help ensure you get the most benefit from your medications.

How Does it Work

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This formulation combines three active ingredients: Azelaic Acid, Clindamycin, and Niacinamide, each with its unique mechanism of action to treat various skin conditions.

Azelaic Acid, at a concentration of 5%, works by helping the skin to renew itself more quickly and therefore reduces pimple and blackhead formation. It also helps to kill the bacteria that can lead to acne and rosacea and it decreases the production of keratin, a natural substance that can lead to the development of acne.

Clindamycin, at a concentration of 1%, is an antibiotic that prevents bacteria from growing on the skin. It works by slowing or stopping the growth of bacteria that cause acne and by decreasing swelling. This helps to improve the overall condition of the skin and reduce the appearance of acne.

Niacinamide, at a concentration of 4%, is a form of Vitamin B3 that has anti-inflammatory properties. It can improve the appearance of enlarged pores, uneven skin tone, fine lines, and dullness. It also helps to build proteins in the skin and lock in moisture to prevent environmental damage.

The semisolid formulation dispensed through a pump mechanism allows for easy and precise application on the skin. The gel-like consistency ensures that the active ingredients are absorbed effectively into the skin for targeted treatment.

This formulation is typically used to treat acne, rosacea, and other inflammatory skin conditions. It can also be used to improve the overall appearance and health of the skin. As with any medication, it is important to use this formulation as directed by a healthcare provider.

If you have any questions about this formulation or how to use it, please don't hesitate to reach out to us at Bayview Pharmacy. Our team of knowledgeable compounding pharmacists is here to help.

Other Uses

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This combination of Azelaic Acid 5%, Clindamycin 1%, and Niacinamide 4% in a Topical Gel form is primarily applied for the treatment of various skin conditions such as acne, rosacea, and hyperpigmentation. However, it does have a variety of other potential uses that might benefit both patients and prescribers.

Firstly, Clindamycin is a well-known antibiotic that effectively battles bacterial skin infections, and can thus be useful as a potential preventative measure against wound infections post-surgery or minor skin injuries. Meanwhile, Azelaic Acid, in addition to its use in combating hyperpigmentation and rosacea, may be used to treat mild forms of melasma, a skin condition that causes dark, discolored patches. It's crucial to note that this should be used under the guidance of a healthcare provider as the strength of Azelaic Acid may affect the pigmentation process.

Niacinamide, a form of vitamin B3, has simultaneously been found to be beneficial for skin health. It plays a critical role in maintaining the skin barrier and improving skin texture, hence it potentially can be used as an adjunctive treatment in managing eczema and other related skin conditions.

However, this formulation should not be used indiscriminately. The person's overall health status, potential allergies, and other pertinent medical history should be evaluated before prescribing. Also, individuals should be counseled on the potential side effects which may include redness, dryness, or irritation at the application site. Peeling may also occur, especially in the initial stages of usage. Across the diverse range of uses, it is noted that the medication may take several weeks to show full effect, requiring patience from the user.

If there are any other uses that you are particularly interested in, or any questions regarding the application or potential side effects of this formulation, please do not hesitate to contact our team at Bayview Pharmacy.

Frequently Asked Questions

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What is Azelaic Acid 5%/Clindamycin 1%/Niacinamide 4% Topical Gel?

This is a semisolid formulation containing azelaic acid, clindamycin, and niacinamide as active ingredients. It is dispensed through a pump mechanism, and it has a gel-like consistency that facilitates easy and precise application on the skin for targeted treatment.

What is the purpose of the pump mechanism?

The pump mechanism is designed to facilitate easy and precise application of the gel to the skin. This ensures that the correct dose is administered each time and prevents wastage of the product.

How does Azelaic Acid 5%/Clindamycin 1%/Niacinamide 4% Topical Gel work?

Azelaic Acid has antibacterial properties and reduces the growth of keratin surface skin cells that can block pores. Clindamycin is an antibiotic, treating acne-causing bacteria on the skin's surface. Niacinamide, or Vitamin B3, helps improve the skin's texture and tone while reducing the appearance of blemishes.

How do I use this topical gel?

Apply the gel to the affected areas of the skin as directed by your healthcare provider. The gel should be spread evenly and absorbed fully into the skin. Avoid contact with the eyes, nose, and mouth.

Does this gel have any side effects?

As with any medication, this gel may cause side effects. Common side effects may include dryness, redness and irritation at the application site. If these persist or get worse, or if you notice other effects, contact your doctor immediately.

Can I apply other skin products while using this gel?

It's recommended to consult with your healthcare provider before incorporating other skincare products into your routine while using this gel. Certain ingredients may interact with the active ingredients in the gel, possibly reducing its effectiveness or causing adverse reactions.

Can this gel be used by individuals with sensitive skin?

This topical gel is generally suitable for all skin types. However, if you have sensitive skin or a known allergy to any of the active ingredients, it's recommended to consult a dermatologist before use. Always conduct a patch test on a small area of skin prior to regular use.

What happens if I miss a dose?

If you miss a dose, apply it as soon as you can. However, if it's close to the time for your next dose, skip the missed dose and stick with your regular dosing schedule. Do not use double the amount to make up for the missed dose.

How should I store the gel?

Store this gel at room temperature. Keep it in a place that is away from heat and moisture. Do not freeze. Keep it out of reach of children and pets.

What should I do in the case of an overdose?

If you suspect an overdose or have used more than the recommended amount of the gel, seek emergency medical help immediately. Symptoms of overdose may include severe redness, peeling, or discomfort.

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Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.

No compounded medications are reviewed by the FDA for safety or efficacy.