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Azelaic Acid 15%/Niacinamide 5% Topical Gel

This formulation is a combination of Azelaic Acid 15% and Niacinamide 5% in a topical gel form. It is a semisolid formulation dispensed through a pump mechanism, which allows for easy and precise application on the skin. The gel-like consistency ensures targeted treatment or absorption of the active ingredients. Azelaic Acid is known for its antibacterial, anti-inflammatory, and exfoliating properties, making it effective in treating conditions like rosacea, acne, and hyperpigmentation. Niacinamide, a form of Vitamin B3, is beneficial for reducing inflammation, improving the skin's barrier function, and minimizing pore appearance and skin roughness. Together, these ingredients work synergistically to treat various skin conditions, promoting healthier and clearer skin.

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Topical Gel
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Formula Information

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This formulation combines Azelaic Acid at a concentration of 15% and Niacinamide at a concentration of 5% in a topical gel. The gel is dispensed through a pump mechanism, which allows for easy and precise application on the skin. The gel-like consistency ensures that the active ingredients are absorbed effectively into the skin for targeted treatment.

Azelaic Acid is a dicarboxylic acid that has been shown to be effective in treating mild to moderate acne by reducing the growth of bacteria in the follicles and decreasing the production of keratin, a natural substance that can lead to the development of acne. It also helps to reduce inflammation and redness associated with acne.

Niacinamide, also known as Vitamin B3, is a potent antioxidant that has been shown to improve the skin's barrier function, reduce skin hyperpigmentation, decrease redness and blotchiness, and reduce the severity of fine lines. It also helps to regulate oil production, which can be beneficial for both dry and oily skin types.

Together, Azelaic Acid and Niacinamide work synergistically to treat a variety of skin conditions. The combination of these two ingredients can help to reduce the appearance of acne, rosacea, and hyperpigmentation, while also improving the overall texture and tone of the skin. This formulation is suitable for all skin types and can be used daily as part of a comprehensive skincare routine.

As with any skincare product, it is recommended to perform a patch test before using this formulation to ensure that it does not cause any adverse reactions. If you experience any irritation or discomfort, discontinue use and consult with a healthcare provider.

If you have any questions about this formulation or how to use it, please do not hesitate to reach out to us. Our team of knowledgeable compounding pharmacists at Bayview Pharmacy is always here to help.

Drug Interactions

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Azelaic Acid 15%/Niacinamide 5% Topical Gel is a specially compounded formulation designed to treat a variety of skin conditions. Azelaic acid is a dicarboxylic acid that has antimicrobial and anti-inflammatory properties, making it effective in the treatment of conditions such as rosacea, acne, and hyperpigmentation. Niacinamide, also known as vitamin B3, has anti-inflammatory effects on the skin and can improve the skin's barrier function, reduce skin hyperpigmentation, and decrease oil production, making it beneficial for conditions such as acne and rosacea.

While this formulation is generally well-tolerated, there are potential interactions that patients and prescribers should be aware of. Azelaic acid and niacinamide are both active ingredients that can cause skin irritation, particularly in individuals with sensitive skin or those who are using other topical treatments. It is important to inform your healthcare provider of all medications and skin care products you are currently using to avoid potential interactions.

Concurrent use of azelaic acid with other skin treatments such as tretinoin, salicylic acid, or benzoyl peroxide may increase the risk of skin irritation. If you are using any of these treatments, it is recommended to apply them at different times of the day to minimize the risk of irritation. For example, you could apply the azelaic acid/niacinamide gel in the morning and the other treatment at night.

Niacinamide can interact with certain medications when taken orally, but these interactions are less likely with topical use. However, if you are taking medications such as anticonvulsants, antituberculosis drugs, or high doses of vitamin A, it is important to inform your healthcare provider as these can interact with niacinamide.

It is also important to note that while niacinamide is generally well-tolerated, some individuals may experience a "niacin flush" - a temporary redness and warming of the skin - after application. This is not harmful and usually subsides within an hour. If you experience persistent or severe flushing, discontinue use and contact your healthcare provider.

As with any medication, it is important to use this formulation as directed by your healthcare provider. Avoid contact with the eyes, mouth, and other mucous membranes. If you experience any adverse reactions such as severe redness, burning, stinging, peeling, or unusual dryness of the skin, discontinue use and contact your healthcare provider immediately.

If you have any questions about this formulation or its potential interactions, please do not hesitate to reach out to us at Bayview Pharmacy. Our knowledgeable team of compounding pharmacists is here to assist you.

How Does it Work

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Azelaic Acid 15%/Niacinamide 5% Topical Gel is a specially formulated compound that combines the therapeutic benefits of both azelaic acid and niacinamide. This formulation is designed to be applied topically, directly onto the skin, where it can exert its effects locally.

Azelaic acid is a naturally occurring acid found in grains like barley, wheat, and rye. It works by helping the skin to renew itself more quickly and therefore reduces pimple and blackhead formation. It also helps to kill the bacteria that can lead to acne and rosacea and it can decrease the production of keratin, a natural substance that can lead to the development of acne. The 15% concentration in this formulation is considered effective for treating mild to moderate acne and rosacea.

Niacinamide, also known as vitamin B3, has a wide range of benefits for the skin. It helps to build proteins in the skin and lock in moisture to prevent environmental damage. It also has the ability to reduce inflammation, which can help with conditions like acne and rosacea. The 5% concentration in this formulation is considered effective for these purposes.

When combined in a topical gel, these two ingredients can work synergistically to treat a variety of skin conditions. The gel formulation allows for easy and precise application, and the pump mechanism ensures that the correct amount of medication is dispensed each time. The gel is designed to be absorbed quickly into the skin, allowing the active ingredients to start working immediately.

This formulation can be used to treat a variety of disease states. It is most commonly used for acne and rosacea, but it can also be used for other conditions characterized by inflammation and/or abnormal keratin production. It can also help to improve the overall texture and tone of the skin, making it a useful addition to many skincare routines.

As with any medication, it's important to use this formulation as directed by your healthcare provider. Side effects can include burning, stinging, or tingling of the skin; dryness or peeling; and redness or other signs of irritation. If these side effects persist or worsen, contact your healthcare provider.

If you have any questions about this formulation, or if you would like to know more about how it can be used to treat specific conditions, please don't hesitate to reach out to us. We are here to help and provide you with the information you need to make informed decisions about your health.

Other Uses

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Frequently Asked Questions

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What is the formulation of Azelaic Acid 15%/Niacinamide 5% Topical Gel?

This is a semisolid formulation that is dispensed through a pump mechanism. It has a gel-like consistency which facilitates easy and precise application on the skin for targeted treatment or absorption of the active ingredients.

How do I use Azelaic Acid 15%/Niacinamide 5% Topical Gel?

You simply dispense this semisolid formulation via a pump mechanism directly to the area of the skin needing treatment. The gel-like consistency of the product makes application easy and precise.

Does the Azelaic Acid 15%/Niacinamide 5% Topical Gel spread easily?

Yes, due to its semisolid, gel-like formulation, this product spreads easily over the skin ensuring a regular application of the active ingredients.

What are the active ingredients in this topical gel?

The primary active ingredients are Azelaic Acid at a 15% concentration and Niacinamide at a 5% concentration.

Is Azelaic Acid 15%/Niacinamide 5% Topical Gel safe for daily use?

Yes, this topical gel is generally safe for daily use. However, this will depend on your skin type and sensitivity, as well as the specific condition being treated. Always consult your healthcare provider for personal instruction.

Where should the Azelaic Acid 15%/Niacinamide 5% Topical Gel be applied?

This gel is designed for targeted treatment, so it should be applied directly to the affected area of the skin as instructed by your healthcare provider.

What does the included pump mechanism of the Azelaic Acid 15%/Niacinamide 5% Topical Gel offer?

The pump mechanism helps facilitate easy and precise dispensing of the product on to the skin.

Can I use other skincare products with Azelaic Acid 15%/Niacinamide 5% Topical Gel?

Talk to your healthcare provider about what other skincare products can be used in conjunction with this gel. Some products may interfere with the absorption and effectiveness of the active ingredients.

Will Azelaic Acid 15%/Niacinamide 5% Topical Gel leave my skin feeling sticky?

No, being a semisolid, gel-like formulation, it is designed to be easily absorbed by the skin without leaving a sticky residue.

Can I use Azelaic Acid 15%/Niacinamide 5% Topical Gel to treat acne?

Yes, Azelaic Acid is commonly used to treat mild to moderate acne. It helps to kill the bacteria that cause acne and to keep the skin pores open. Furthermore, Niacinamide is effective in reducing inflammation, which can help manage acne. However, always consult your healthcare provider for personal instruction.

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Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.

No compounded medications are reviewed by the FDA for safety or efficacy.