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Ascorbic Acid 2%/Glycolic Acid 8%/Hydroquinone 5%/Tranexamic Acid 2% Topical Gel

This Ascorbic Acid 2%/Glycolic Acid 8%/Hydroquinone 5%/Tranexamic Acid 2% Topical Gel is a specially formulated semisolid preparation. It is dispensed through a pump mechanism, which allows for easy and precise application on the skin. The gel-like consistency ensures targeted treatment or absorption of the active ingredients.

The formulation is designed to treat a variety of disease states. Ascorbic Acid, a form of Vitamin C, is known for its antioxidant properties and aids in skin repair. Glycolic Acid, an alpha-hydroxy acid, is used for its exfoliating and skin-smoothing properties. Hydroquinone is a skin-lightening agent used to treat conditions like melasma and hyperpigmentation. Tranexamic Acid is used to treat or prevent excessive blood loss from major trauma, post partum bleeding, surgery, tooth removal, nosebleeds, and heavy menstruation.

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Topical Gel
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Formula Information

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This formulation is a unique blend of Ascorbic Acid 2%, Glycolic Acid 8%, Hydroquinone 5%, and Tranexamic Acid 2% in a topical gel form. It is designed to be dispensed through a pump mechanism, which allows for easy and precise application on the skin. The gel-like consistency ensures that the active ingredients are absorbed effectively for targeted treatment.

Ascorbic Acid, also known as Vitamin C, is a potent antioxidant that aids in the skin's natural regeneration process. It helps the body repair damaged skin cells, leading to healthier and brighter skin. It also boosts collagen production, which can help reduce the appearance of wrinkles and improve overall skin texture.

Glycolic Acid is an alpha-hydroxy acid (AHA) that exfoliates the skin, removing the outermost layer of dead cells and revealing brighter, fresher skin underneath. It can also stimulate the production of new skin cells, improving the skin's appearance and texture.

Hydroquinone is a skin-lightening agent that can help treat conditions like melasma, age spots, and other forms of hyperpigmentation. It works by decreasing the production and increasing the breakdown of melanin pigments in the skin. This can result in a more even skin tone and reduced appearance of dark spots.

Tranexamic Acid is a powerful ingredient that can help treat melasma and post-inflammatory hyperpigmentation. It works by inhibiting the activation of melanocytes, the cells that produce melanin, which can lead to a reduction in pigmentation.

This formulation is designed to treat a variety of skin conditions, including hyperpigmentation, melasma, age spots, and uneven skin tone. It can also help improve the overall appearance and texture of the skin, making it brighter, smoother, and more youthful-looking.

As with any medication, it's important to use this formulation as directed by your healthcare provider. Side effects may include skin irritation, redness, or dryness. If you experience any severe or persistent side effects, contact your healthcare provider immediately.

If you have any questions about this formulation or how to use it, don't hesitate to reach out to us. We're here to help and provide you with the information you need to make informed decisions about your health.

Drug Interactions

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This formulation contains Ascorbic Acid, Glycolic Acid, Hydroquinone, and Tranexamic Acid, all of which have their unique properties and potential interactions. It is important to note that while this formulation is designed for topical use, systemic absorption can still occur, especially with prolonged use or application on large skin areas. Therefore, potential drug interactions should not be overlooked.

Ascorbic Acid (Vitamin C) is generally considered safe with minimal interactions. However, it can increase the absorption of iron, so caution should be exercised in patients with hemochromatosis or other iron overload conditions. It may also decrease the efficacy of certain chemotherapy drugs, so it's important to consult with a healthcare provider if you are undergoing cancer treatment.

Glycolic Acid is an alpha-hydroxy acid used in skincare for its exfoliating properties. It can increase skin sensitivity, particularly to sunlight, so it's important to use sun protection while using this formulation. Glycolic Acid may also increase the absorption of other topical medications, potentially enhancing their effects and side effects.

Hydroquinone is a skin-lightening agent that can interact with products containing peroxides (benzoyl peroxide, hydrogen peroxide), causing a temporary staining of the skin. It's also important to avoid using other skin products that can cause irritation, such as harsh soaps, shampoos, or skin cleansers, hair coloring or permanent chemicals, hair removers or waxes, or skin products with alcohol, spices, astringents, or lime.

Tranexamic Acid is an antifibrinolytic that is used topically in this formulation for its skin-lightening properties. While systemic absorption is minimal, it can theoretically increase the risk of clotting if absorbed systemically, especially in patients with a history of thromboembolic disease or those taking oral contraceptives or hormone replacement therapy. It may also interact with other anticoagulants or antiplatelet drugs, potentially increasing the risk of bleeding.

This formulation is designed to treat hyperpigmentation disorders such as melasma, post-inflammatory hyperpigmentation, and age spots. The combination of these active ingredients works to inhibit melanin production, exfoliate the skin to remove existing pigmentation, and provide antioxidant protection. However, it's important to use this product under the supervision of a healthcare provider due to the potential for skin irritation and other side effects.

If you have any questions about this formulation or its potential interactions, please don't hesitate to reach out to us. We are here to help ensure that you can use this product safely and effectively.

How Does it Work

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This formulation is a combination of four active ingredients: Ascorbic Acid, Glycolic Acid, Hydroquinone, and Tranexamic Acid, each playing a unique role in treating various skin conditions.

Ascorbic Acid, also known as Vitamin C, is a potent antioxidant that neutralizes free radicals on the skin. It aids in the skin's natural regeneration process, which helps the body repair damaged skin cells. Ascorbic Acid also boosts collagen production, which can help reduce the appearance of wrinkles and improve overall skin texture.

Glycolic Acid is an alpha-hydroxy acid (AHA) that exfoliates the skin, helping to get rid of the dead skin cells that can clog pores. As a result, the skin appears brighter and smoother. Glycolic Acid also stimulates the production of new skin cells, reducing the appearance of fine lines, acne scars, and dark spots.

Hydroquinone is a skin-lightening agent. It works by decreasing the production and increasing the breakdown of melanin pigments in the skin. This action will result in lighter skin and the reduction of dark spots and freckles.

Tranexamic Acid is a synthetic derivative of the amino acid lysine. It works by inhibiting plasmin, an enzyme that, when overactive, can lead to excessive melanin production. By controlling this enzyme, Tranexamic Acid helps to reduce pigmentation, including post-inflammatory hyperpigmentation caused by acne or other skin injuries.

The gel formulation allows for easy and precise application, ensuring that the active ingredients are targeted to the area of the skin that requires treatment. The gel-like consistency also aids in the absorption of the active ingredients into the skin, enhancing their effectiveness.

This formulation is used to treat a variety of skin conditions, including hyperpigmentation, melasma, acne scars, and signs of aging. It works by exfoliating the skin, reducing melanin production, boosting collagen production, and neutralizing free radicals. The result is brighter, smoother, and more even-toned skin.

If you have any questions about this formulation, please don't hesitate to reach out to us. We are here to help you understand how this formulation works and how it can benefit your skin.

Other Uses

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Beyond its primary uses in treating hyperpigmentation, melasma, and certain types of acne, this combination of Ascorbic Acid, Glycolic Acid, Hydroquinone, and Tranexamic Acid can serve other therapeutic purposes. The Ascorbic Acid 2%/Glycolic Acid 8%/Hydroquinone 5%/Tranexamic Acid 2% Topical Gel formulation is full of ingredients known for their abilities to rejuvenate and brighten the skin. Ascorbic Acid, also known as Vitamin C, can be used as a potent antioxidant, helping to protect the skin from free radical damage. Glycolic Acid, an Alpha Hydroxy Acid, is frequently used in chemical peels to reduce fine lines, acne, blackheads, and oiliness. The hydroquinone in the formulation might be used off-label to lighten age spots and other areas of unwanted pigmentation.

Additionally, Tranexamic Acid has been recognized for its potential use in managing rosacea and post-inflammatory erythema (PIE), making the topical gel potentially suitable for those with these conditions, albeit off-label. Patients who have undergone laser treatments, chemical peels, or other forms of skin resurfacing might also benefit from this topical formulation, as the skin-rejuvenating properties can aid in the overall recovery and appearance of their skin post-procedure. However, it's essential to consult with a healthcare professional before incorporating it into your skincare regimen for these unapproved uses, especially in consideration of potential adverse reactions or contraindications.

Prior to using this formulation, both patients and prescribers should note that extended use of hydroquinone could potentially result in increased sun sensitivity and a skin condition known as ochronosis, characterized by the darkening of the skin where the product has been applied. As such, it should only be used on a short-term basis (not exceeding four months). Additionally, it's essential to use sun protection measures, including wearing sun-protective clothing, sunscreen, and avoiding direct sunlight whenever possible, while using and for a week after discontinuing this medication. For any questions, please reach out to us at Bayview Pharmacy, where our knowledgeable team of compounding pharmacists is ready to assist you.

Frequently Asked Questions

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What is this compounded formulation made of?

The formulation is composed of Ascorbic Acid 2%, Glycolic Acid 8%, Hydroquinone 5%, and Tranexamic Acid 2%.

What form does this medication come in?

This medication is available as a semisolid formulation that's dispensed via a pump mechanism for easy and precise application on your skin.

What is the consistency of this medication?

The preparation is like a gel, ensuring easy application and targeted treatment.

How does the pump mechanism work?

The pump mechanism allows for easy and precise dispensing of the medication on the skin, allowing for accurate dosage and application.

Is the application of this topical gel easy?

Yes, the gel formulation and pump mechanism simplifies the application process and aids precise targeting for the desired treatment area.

Where should I apply this topical gel?

The gel is designed for skin application. It should be directly applied to the affected area as directed by the healthcare provider.

Can this topical gel be used for targeted treatment?

Yes, the convenience of the pump mechanism allows you to easily control the amount dispensed, resulting in targeted treatment of the affected skin area.

How do the active ingredients in the formulation work?

The Ascorbic Acid, Glycolic Acid, Hydroquinone, and Tranexamic Acid in the formulation work together in treatment. These active ingredients are absorbed by the skin for the desired effect.

What skin conditions can this medication treat?

The formulation of Ascorbic Acid 2%/Glycolic Acid 8%/Hydroquinone 5%/Tranexamic Acid 2% topical gel can address a range of skin conditions as determined by your healthcare provider.

Can I use this topical gel anywhere on my body?

While the topical gel is generally safe, it's always recommended to follow your healthcare provider's instructions on where and how to apply this medication.

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Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.

No compounded medications are reviewed by the FDA for safety or efficacy.