This formulation is a compounded topical gel containing Amitriptyline HCl 2%, Gabapentin 10%, Ketamine HCl 2.3%, Ketoprofen 10%, and Lidocaine HCl 5%. It is a semisolid formulation that is dispensed through a pump mechanism, allowing for easy and precise application on the skin. The gel-like consistency ensures that the active ingredients are absorbed effectively into the targeted area for optimal therapeutic effect.

Amitriptyline HCl is a tricyclic antidepressant that is used in this formulation for its analgesic properties. It can help to alleviate chronic pain, particularly neuropathic pain. Gabapentin is an anticonvulsant that is also used for its analgesic properties, particularly in treating neuropathic pain. Ketamine HCl is a powerful anesthetic that provides rapid pain relief. Ketoprofen is a nonsteroidal anti-inflammatory drug (NSAID) that reduces inflammation and pain. Lidocaine HCl is a local anesthetic that provides immediate relief from pain by numbing the skin and underlying tissues.

This formulation is particularly useful in treating various disease states that involve chronic pain, inflammation, and neuropathic pain. These may include conditions such as fibromyalgia, post-herpetic neuralgia, diabetic neuropathy, and other similar conditions. The combination of these active ingredients provides a multi-modal approach to pain management, targeting different pain pathways to provide comprehensive relief.

Patients using this formulation should apply it to the affected area as directed by their healthcare provider. It is important to wash hands immediately after application and avoid contact with eyes, mouth, and other mucous membranes. Side effects may include skin irritation at the application site, and systemic side effects are rare but may include drowsiness, dizziness, or confusion. Patients should report any unusual side effects to their healthcare provider immediately.

Prescribers should consider this formulation for patients who have not responded to traditional oral pain medications, or for those who cannot tolerate them due to side effects. It may also be a suitable option for patients who prefer a topical treatment over oral medications. As with all medications, it is important to consider the patient's overall health status, other medications, and potential drug interactions when prescribing this formulation.

If you have any questions about this formulation, please do not hesitate to reach out to us at Bayview Pharmacy. Our knowledgeable team of compounding pharmacists is always here to assist you.

This compounded formulation contains several active ingredients, each with its own potential for drug interactions. It is important to consider these interactions when prescribing or using this medication.

Amitriptyline HCl is a tricyclic antidepressant that can interact with a variety of medications. It can increase the effects of other CNS depressants, such as alcohol, barbiturates, and benzodiazepines, leading to increased sedation. It can also interact with other antidepressants, leading to an increased risk of serotonin syndrome. Additionally, it can decrease the effectiveness of certain blood pressure medications.

Gabapentin is an anticonvulsant that can also interact with a variety of medications. It can increase the effects of other CNS depressants, leading to increased sedation. It can also decrease the effectiveness of certain antacids, so it is recommended to take gabapentin at least 2 hours after taking an antacid.

Ketamine HCl is a general anesthetic that can interact with a variety of medications. It can increase the effects of other CNS depressants, leading to increased sedation. It can also interact with certain antibiotics, leading to an increased risk of seizures.

Ketoprofen is a nonsteroidal anti-inflammatory drug (NSAID) that can interact with a variety of medications. It can increase the risk of bleeding when taken with other NSAIDs, anticoagulants, or antiplatelet drugs. It can also decrease the effectiveness of certain blood pressure medications.

Lidocaine HCl is a local anesthetic that can interact with a variety of medications. It can increase the effects of other CNS depressants, leading to increased sedation. It can also interact with certain heart medications, leading to an increased risk of heart problems.

This formulation is used to treat a variety of disease states. Amitriptyline HCl and gabapentin can help to manage neuropathic pain. Ketamine HCl can provide general pain relief. Ketoprofen can help to reduce inflammation and pain. Lidocaine HCl can provide local pain relief.

It is important to discuss all medications, including over-the-counter drugs and supplements, with your healthcare provider before starting this medication. If you have any questions about this formulation or its potential interactions, please reach out to us at Bayview Pharmacy.

This topical gel formulation combines five active ingredients: Amitriptyline HCl, Gabapentin, Ketamine HCl, Ketoprofen, and Lidocaine HCl. Each of these ingredients plays a unique role in managing various disease states, primarily those related to pain and inflammation.

Amitriptyline HCl is a tricyclic antidepressant that is used in this formulation for its analgesic properties. It works by increasing the levels of certain chemicals in the brain that help elevate mood and reduce the sensation of pain. When applied topically, it can help to numb the skin and underlying tissues, providing relief from localized pain.

Gabapentin is an anticonvulsant that is often used to treat nerve pain. It works by stabilizing electrical activity in the brain which helps to reduce the intensity and frequency of nerve pain. In a topical formulation, Gabapentin can provide targeted relief from pain and discomfort.

Ketamine HCl is a powerful anesthetic that works by blocking the signals from the nerves to the brain. This helps to numb the area where the gel is applied, providing immediate relief from pain. It is particularly effective in managing severe or chronic pain conditions.

Ketoprofen is a nonsteroidal anti-inflammatory drug (NSAID) that works by reducing hormones that cause inflammation and pain in the body. When applied topically, it can help to reduce inflammation and provide relief from pain and swelling in the targeted area.

Lidocaine HCl is a local anesthetic that works by blocking nerve signals in your body. It is used to reduce pain or discomfort caused by skin irritations. In this formulation, it works to numb the skin and underlying tissues, providing immediate relief from pain.

The combination of these five active ingredients in a single topical gel allows for targeted treatment of various disease states. The gel is easily applied to the skin, allowing for precise application and absorption of the active ingredients. This can provide significant relief from pain and inflammation, improving the quality of life for patients suffering from these conditions.

If you have any questions about this formulation or how it works, please don't hesitate to reach out to us at Bayview Pharmacy. Our team of knowledgeable compounding pharmacists is always here to help.

This topical gel formulation containing amitriptyline HCl, gabapentin, ketamine HCl, ketoprofen, and lidocaine HCl, typically recommended for conditions associated with severe and chronic pain, might also be used off-label for other purposes. It might be considered as an option for managing muscle spasms and stiffness in conditions, such as multiple sclerosis or following stroke, due to the potential muscle relaxant and anti-spastic properties of some of its ingredients.

In addition, some ingredients of this formulation, such as amitriptyline and gabapentin, have been found to be potentially effective in treating some forms of neuropathic pain. Therefore, it could potentially be used to alleviate discomfort caused by nerve damage in conditions such as diabetic neuropathy or postherpetic neuralgia, among others. Also, the presence of ketoprofen, a non-steroidal anti-inflammatory drug (NSAID), might suggest its application for conditions characterized by inflammation, including some forms of dermatitis or arthritis, as adjunctive topical therapy.

The presence of lidocaine in the formulation, a well-known local anesthetic, might make this topical gel product suitable for use prior to minor skin procedures, through numbing the area to reduce discomfort. Although this is not the primary use of the product, it could be notably helpful under the supervision of a medical specialist. Lastly, due to the sedative and analgesic properties of ketamine, this formulation can, theoretically, be used for temporary relief of symptoms associated with conditions, such as fibromyalgia or migraine, where central sensitization is believed to play a part.

However, it is important to note that these are potential off-label uses, and the effectiveness and safety of the product for these uses might not be as well studied or established. Therefore, these uses should only be considered under the careful supervision of a healthcare provider, and patients or prescribers with questions regarding these alternative uses should reach out to us at Bayview Pharmacy or their healthcare professional for more information.