This formulation is a compounded topical gel containing Amitriptyline HCl 7.5mg/g, Ketamine HCl 5.75mg/g, Ketoprofen 10mg/g, and Lidocaine 5mg/g. It is a semisolid formulation that is dispensed through a pump mechanism, which allows for easy and precise application on the skin. The gel-like consistency ensures that the active ingredients are absorbed effectively into the targeted area.

Amitriptyline HCl is a tricyclic antidepressant that is used in this formulation for its analgesic properties. It works by increasing the levels of certain chemicals in the brain that help elevate mood and reduce the sensation of pain. Ketamine HCl is a powerful anesthetic that provides rapid pain relief by blocking the NMDA receptors in the brain and spinal cord, which are involved in transmitting pain signals. Ketoprofen is a nonsteroidal anti-inflammatory drug (NSAID) that reduces inflammation and pain by inhibiting the production of prostaglandins, substances in the body that cause inflammation. Lidocaine is a local anesthetic that works by blocking nerve signals in your body, providing temporary relief of pain or discomfort in the area where it is applied.

This formulation is commonly used to manage chronic pain conditions, such as neuropathic pain, fibromyalgia, and arthritis. It can also be used to treat localized pain from injuries or surgical procedures. The combination of these four active ingredients provides a multi-modal approach to pain management, targeting different pain pathways to provide comprehensive relief.

It is important to use this medication as directed by your healthcare provider. Apply a thin layer of the gel to the affected area and rub in gently until it is absorbed. Do not apply more than the recommended dose, and avoid contact with eyes, mouth, and open wounds. If you experience any adverse reactions, such as skin irritation or allergic reactions, discontinue use and contact your healthcare provider immediately.

As compounding pharmacists, we are able to customize this formulation to meet individual patient needs, such as adjusting the concentration of the active ingredients or changing the base to accommodate for skin sensitivities. If you have any questions or concerns about this formulation, please do not hesitate to reach out to us at Bayview Pharmacy. We are here to help.

This formulation combines four active ingredients: Amitriptyline HCl, Ketamine HCl, Ketoprofen, and Lidocaine. Each of these ingredients has a specific role in managing pain and inflammation, but they may also interact with other medications. It's important to understand these potential interactions to ensure safe and effective use of this formulation.

Amitriptyline HCl is a tricyclic antidepressant that can help manage chronic pain. It may interact with MAO inhibitors, SSRIs, anticholinergic drugs, and certain heart medications. Combining amitriptyline with these drugs can increase the risk of side effects such as serotonin syndrome, heart problems, and anticholinergic effects like dry mouth and constipation.

Ketamine HCl is an NMDA receptor antagonist used for its analgesic properties. It may interact with CNS depressants, opioids, and certain anesthetics, potentially leading to increased sedation, respiratory depression, and changes in blood pressure. It's important to monitor patients closely when these drugs are used together.

Ketoprofen is a nonsteroidal anti-inflammatory drug (NSAID) that can reduce pain and inflammation. It may interact with anticoagulants, ACE inhibitors, diuretics, and other NSAIDs. These interactions can increase the risk of bleeding, kidney problems, and gastrointestinal issues. Patients should be monitored for signs of these complications.

Lidocaine is a local anesthetic that can numb the skin and relieve pain. It may interact with other local anesthetics and certain heart medications. These interactions can increase the risk of lidocaine toxicity, which can cause symptoms like dizziness, seizures, and heart problems.

This formulation is designed to be applied topically, which can reduce the risk of systemic side effects and interactions. However, it's still important to consider potential interactions, especially in patients who are using other topical medications or have compromised skin integrity.

This formulation can be used to manage various disease states associated with pain and inflammation, such as neuropathic pain, osteoarthritis, and post-herpetic neuralgia. By combining multiple active ingredients, it can target different pain pathways and provide more comprehensive relief.

If you have any questions about this formulation or its potential interactions, please don't hesitate to reach out to us. We're here to help ensure that you can use this medication safely and effectively.

This formulation is a combination of four active ingredients: Amitriptyline HCl, Ketamine HCl, Ketoprofen, and Lidocaine, each playing a unique role in managing pain and inflammation. The formulation is designed to be applied topically, directly to the skin, where it can be absorbed to provide targeted relief.

Amitriptyline HCl is a tricyclic antidepressant that is used in this formulation for its analgesic properties. It works by increasing the levels of certain chemicals in the brain that help elevate mood and reduce the sensation of pain. When applied topically, Amitriptyline HCl can help to numb the skin and underlying tissues, reducing pain in the applied area.

Ketamine HCl is a powerful anesthetic that works by blocking the NMDA receptors in the brain and spinal cord, which play a significant role in modulating pain. In this topical formulation, Ketamine HCl can provide profound pain relief in the area of application without causing the systemic side effects associated with its oral or injectable use.

Ketoprofen is a nonsteroidal anti-inflammatory drug (NSAID) that works by reducing the production of prostaglandins, chemicals that cause inflammation, pain, and fever in the body. When applied topically, Ketoprofen can reduce inflammation and pain in the area of application.

Lidocaine is a local anesthetic that works by blocking the nerve signals in your body. It is used to reduce pain or discomfort caused by skin irritations such as sunburn, insect bites, poison ivy, poison oak, poison sumac, and minor cuts, scratches, or burns. In this formulation, Lidocaine provides immediate, localized pain relief.

The gel formulation allows for easy and precise application, and the pump mechanism ensures that the correct dose is dispensed each time. The gel is designed to be absorbed through the skin, delivering the active ingredients directly to the area that needs treatment. This targeted approach can provide faster, more effective relief than oral medications, and with fewer systemic side effects.

This formulation can be used to treat a variety of disease states that involve pain and inflammation, including but not limited to neuropathic pain, arthritis, sports injuries, and post-surgical pain. As with any medication, it is important to use this formulation as directed by your healthcare provider, and to discuss any potential side effects or interactions with other medications you are taking.

If you have any questions about this formulation, or if you would like more information about how it can be used to treat specific conditions, please don't hesitate to reach out to us at Bayview Pharmacy. Our team of knowledgeable compounding pharmacists is always here to help.

This compounded formulation of Amitriptyline HCl 7.5/Ketamine HCl 5.75/Ketoprofen 10/Lidocaine 5 in a topical gel form is primarily used for the management of local pain and inflammation. Its unique blend of active ingredients helps alleviate pain and discomfort in a targeted area, thus maximizing its therapeutic effect while limiting systemic exposure.

Aside from its main use, this formulation may also be beneficial in other medical circumstances. Amitriptyline, a tricyclic antidepressant, can subtly alter the processing of pain signals in the central nervous system, making it potentially useful for neuropathic pain conditions such as diabetic neuropathy, post-herpetic neuralgia, and migraines. Furthermore, the addition of ketamine, an NMDA antagonist, can aid in the management of refractory chronic pain syndromes that fail to respond to standard pain management.

Ketoprofen, being a non-steroidal anti-inflammatory drug (NSAID), has analgesic, anti-inflammatory, and antipyretic properties. Thus, it may be also beneficial for conditions that involve joint and muscle pain, such as osteoarthritis and rheumatoid arthritis. Furthermore, lidocaine, a local anesthetic, temporarily relieves pain from minor skin irritations, burns, and abrasions.

The versatile combination of these medications might provide relief in the management of other off-label conditions, including lower back pain, sports injuries, and systemic disorders affecting the skin. It is also possible that it could be used in palliative care to provide comfort to patients with chronic, intractable pain. Of course, all these alternative uses should be explored under the guidance and careful monitoring of a qualified healthcare professional.

This information aims to enhance patients' understanding as well as serve as a comprehensive guide for prescribers interested in this topical gel formulation. We encourage both patients and healthcare professionals to contact us with any further inquiries or details about the potential uses of this medication. As compounding pharmacists, we can customize this medication to cater to patient-specific needs and offer in-depth counsel for its maximum benefit.