This formulation is a compounded transdermal gel containing Amitriptyline 2%, Gabapentin 6%, Ketamine 10%, and Lidocaine 5%. It is a semisolid formulation that is dispensed through a pump mechanism, which allows for easy and precise application on the skin. The gel-like consistency ensures that the active ingredients are absorbed directly into the targeted area, providing localized relief.

Amitriptyline is a tricyclic antidepressant that is used in this formulation for its analgesic properties. It works by increasing the levels of certain chemicals in the brain that help elevate mood and reduce the sensation of pain. Gabapentin is an anticonvulsant and nerve pain medication that is used to treat nerve pain conditions. It works by stabilizing electrical activity in the brain and affects the way the nerves send messages to the brain.

Ketamine is a powerful anesthetic that provides pain relief by blocking certain receptors in the brain. It is used in this formulation for its potent analgesic effects. Lidocaine is a local anesthetic that works by causing temporary numbness in the area where it is applied. It works by blocking nerve signals in your body and is used in this formulation to provide immediate relief from pain and discomfort.

This formulation is commonly used to treat various disease states that involve chronic pain, such as neuropathic pain, fibromyalgia, and post-herpetic neuralgia. It can also be used to manage pain in conditions like arthritis and nerve injuries. The combination of these four active ingredients provides both immediate and long-term relief from pain and discomfort, improving the quality of life for patients suffering from these conditions.

It is important to note that this formulation should be used as directed by a healthcare provider. The dose and frequency of application will depend on the individual patient's condition and response to treatment. Side effects may include skin irritation at the application site, dizziness, drowsiness, or changes in mood or behavior. If any of these side effects persist or worsen, contact your healthcare provider immediately.

If you have any questions about this formulation or its use, please do not hesitate to reach out to us at Bayview Pharmacy. Our team of knowledgeable compounding pharmacists is always here to assist you.

This compounded formulation contains Amitriptyline, Gabapentin, Ketamine, and Lidocaine, all of which are medications used to manage pain. Amitriptyline is a tricyclic antidepressant that can help manage chronic pain. Gabapentin is an anticonvulsant that can also help manage nerve pain. Ketamine is a powerful anesthetic that can provide significant pain relief. Lidocaine is a local anesthetic that can numb the skin and provide immediate pain relief.

It's important to be aware of potential drug interactions when using this formulation. Amitriptyline can interact with MAO inhibitors, SSRIs, anticholinergics, and other tricyclic antidepressants. It can also interact with certain antihypertensive medications and can increase the effects of alcohol. Gabapentin can interact with antacids, morphine, hydrocodone, and certain antiviral medications. Ketamine can interact with CNS depressants, including alcohol, benzodiazepines, and opioids. Lidocaine can interact with other local anesthetics and certain heart medications.

Patients should inform their healthcare provider of all medications they are currently taking, including prescription drugs, over-the-counter medications, and herbal supplements. This will help the healthcare provider to prevent potential drug interactions.

This formulation is applied topically, which can reduce the risk of systemic side effects and drug interactions. However, it's still possible for these medications to be absorbed through the skin and into the bloodstream, especially if the skin is broken or irritated. Therefore, patients should use this medication exactly as directed by their healthcare provider.

This formulation can be used to treat various disease states that involve chronic or severe pain. This can include conditions like fibromyalgia, neuropathic pain, post-herpetic neuralgia, and certain types of arthritis. It can also be used to manage pain associated with cancer or cancer treatment.

Patients should monitor their symptoms and report any changes to their healthcare provider. If the pain worsens or if new symptoms develop, the healthcare provider may need to adjust the treatment plan. Patients should also report any side effects they experience, including skin irritation, dizziness, confusion, or changes in mood or behavior.

If you have any questions about this formulation or its use, please don't hesitate to reach out to us. We're here to help and provide the information you need to use this medication safely and effectively.

This formulation is a combination of four active ingredients: Amitriptyline, Gabapentin, Ketamine, and Lidocaine, each playing a unique role in managing pain. The formulation is designed to be applied topically, directly to the skin, where it is absorbed into the body to provide targeted relief.

Amitriptyline is a tricyclic antidepressant that works by increasing the levels of certain chemicals in the brain that help improve mood, sleep, and the body's response to pain. In this formulation, it is used for its analgesic properties, particularly in neuropathic pain.

Gabapentin is an anticonvulsant that is often used to treat seizures and nerve pain. It works by calming down nerve activity, thus reducing pain sensation. In this formulation, it is used for its ability to manage neuropathic pain.

Ketamine is a powerful anesthetic that works by blocking certain receptors in the brain that are responsible for transmitting pain signals. In this formulation, it is used for its potent analgesic properties, providing relief from severe or chronic pain.

Lidocaine is a local anesthetic that works by blocking nerve signals in your body. It is used topically to reduce pain or discomfort caused by skin irritations. In this formulation, it provides immediate, localized relief from pain.

The transdermal gel formulation allows for the active ingredients to be absorbed directly through the skin, providing targeted relief. The gel is dispensed through a pump mechanism, which allows for easy and precise application. This is particularly beneficial for patients who may have difficulty swallowing pills or for those who prefer not to take medication orally.

This formulation is particularly effective in treating conditions such as neuropathic pain, fibromyalgia, and other chronic pain conditions. The combination of these four active ingredients works synergistically to provide comprehensive pain relief, addressing both the physical sensation of pain and the emotional distress that can accompany chronic pain conditions.

If you have any questions about this formulation, how it works, or how it can be used to treat specific conditions, please don't hesitate to reach out to us. We are here to help and provide the information you need to make informed decisions about your health.

This specially compounded Amitriptyline 2%/Gabapentin 6%/Ketamine 10%/Lidocaine 5% Transdermal Gel can have several other uses besides those previously prescribed. First and foremost, while the formulation is commonly used for neuropathic pain management, it actually has a much broader application. Other therapeutic indications include fibromyalgia, complex regional pain syndrome, or other chronic pain conditions. With its combination of components, it serves to manage nociceptive, neuropathic, and centralized pain states effectively.

Secondly, due to its local anaesthetic property from the Lidocaine component, it can be used in smaller doses for local anaesthesia effect for minor surgical procedures or diagnostic procedures requiring superficial anaesthesia. The gel is easy to apply and non-systemic, hence minimizing side effects.

In addition to the above, the gabapentin in the formulation enhances the analgesic effect but has also been indicated for conditions such as postherpetic neuralgia, diabetic neuropathy and even off-label uses like anxiety disorders and restless legs syndrome. Amitriptyline, an antidepressant, has been found useful in managing various mental/mood problems like depression and even in preventing migraines. Ketamine, on the other hand, can potentially be effective for depression or suicidal ideation when used in lower doses, under medical supervision. Thus, this formulation leverages the multi-modal advantages of its ingredients.

It's crucial for patients and prescribers to understand that this formulation not only provides targeted pain relief but also shows potential for other health issues. However, it should only be used under a healthcare provider's guidance considering the intoxicating effects of some of its ingredients like ketamine and potential interaction of components like gabapentin and amitriptyline with other substances. Our knowledgeable team of compounding pharmacists at Bayview Pharmacy is always ready to assist with any inquiries about this formulation, its potential uses, and its applicability to individual patient situations. Please do not hesitate to reach out to us with any questions.