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Aluminum Chloride Hexahydrate 40%/Salicylic Acid 4% Topical Gel

This Aluminum Chloride Hexahydrate 40%/Salicylic Acid 4% Topical Gel is a semisolid formulation designed for the effective treatment of hyperhidrosis and keratolytic conditions. It is dispensed through a pump mechanism, allowing for easy and precise application on the skin. The gel-like consistency ensures targeted treatment and optimal absorption of active ingredients, providing relief from excessive sweating and aiding in the exfoliation of dead skin cells.

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Aluminum Chloride Hexahydrate
Salicylic Acid
Topical Gel
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Formula Information

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This Aluminum Chloride Hexahydrate 40% and Salicylic Acid 4% Topical Gel is a compounded medication designed to provide targeted relief for individuals experiencing excessive sweating. The combination of these active ingredients in a gel formulation allows for enhanced absorption and effectiveness in controlling perspiration.

Aluminum Chloride Hexahydrate is a potent antiperspirant agent that works by temporarily blocking the sweat ducts, thereby reducing the amount of sweat that reaches the skin's surface. At a concentration of 40%, it offers significant efficacy for those who have not responded to standard over-the-counter antiperspirants.

Salicylic Acid at a 4% concentration acts as a keratolytic agent, promoting the shedding of dead skin cells and enhancing the penetration of Aluminum Chloride Hexahydrate. This synergy not only increases the effectiveness of the antiperspirant but also helps minimize potential skin irritation by facilitating smoother application.

The gel is dispensed through a convenient pump mechanism, ensuring precise and controlled application to the affected areas. Its semisolid consistency allows for easy spreading and quick absorption without leaving a sticky residue, making it suitable for use on various parts of the body prone to excessive sweating.

For optimal results, apply the gel to clean, dry skin, preferably at night when sweating is typically reduced. This allows the active ingredients to work uninterrupted. In the morning, you may wash the treated area to remove any residual product. Avoid applying the gel to broken or irritated skin, and do not use it immediately after shaving to prevent adverse reactions.

It is important to use this medication as directed by your healthcare provider. If you experience any severe irritation, redness, or other unexpected side effects, discontinue use and consult your provider promptly. They can provide guidance on how to manage any side effects or adjust your treatment plan if necessary.

Store the gel at room temperature, away from excessive heat and moisture. Keep the container tightly closed when not in use to maintain the efficacy of the medication. As with all medications, keep it out of reach of children and pets.

If you have any questions or concerns about this formulation or its use, please do not hesitate to reach out to us. Our team at Bayview Pharmacy is here to provide support and answer any questions you may have.

Drug Interactions

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Aluminum Chloride Hexahydrate 40%/Salicylic Acid 4% Topical Gel is a compounded formulation designed for the treatment of hyperhidrosis and certain dermatological conditions such as acne, warts, and psoriasis. This formulation combines the astringent properties of aluminum chloride hexahydrate with the keratolytic effects of salicylic acid, providing a dual-action approach to managing excessive sweating and promoting skin exfoliation.

When considering the use of this topical gel, it is important to be aware of potential drug interactions that may affect its efficacy or increase the risk of adverse effects. Patients and prescribers should be cautious when using this formulation concurrently with other topical or systemic medications. The presence of salicylic acid, a beta-hydroxy acid, may enhance the absorption of other topical agents, potentially leading to increased systemic exposure. This is particularly relevant for medications with narrow therapeutic indices or those that are known to cause systemic toxicity.

Concomitant use of other topical preparations containing salicylic acid or similar keratolytic agents should be avoided to prevent cumulative irritation or excessive skin peeling. Additionally, the use of aluminum chloride hexahydrate may interact with other antiperspirants or deodorants, potentially leading to increased skin irritation or reduced effectiveness of the treatment. Patients should be advised to avoid applying other topical products to the same area unless specifically directed by their healthcare provider.

Systemic medications, such as aspirin or other salicylates, may also interact with the salicylic acid component of the gel. Although the systemic absorption of salicylic acid from topical application is generally low, caution is advised in patients who are taking high doses of oral salicylates or who have a history of salicylate sensitivity. Monitoring for signs of salicylate toxicity, such as tinnitus or gastrointestinal disturbances, may be warranted in these cases.

Patients with renal impairment should use this formulation with caution, as both aluminum and salicylic acid can accumulate in cases of reduced renal function, potentially leading to toxicity. It is advisable for prescribers to assess renal function before initiating treatment and to monitor for any signs of adverse effects during therapy.

In summary, while Aluminum Chloride Hexahydrate 40%/Salicylic Acid 4% Topical Gel is an effective treatment for certain dermatological conditions, careful consideration of potential drug interactions is essential to ensure safe and effective use. Patients and prescribers should communicate openly about all medications being used, including over-the-counter products and supplements, to avoid any unintended interactions. If you have any questions or require further information, please reach out to us at Bayview Pharmacy.

How Does it Work

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The Aluminum Chloride Hexahydrate 40%/Salicylic Acid 4% Topical Gel is a specialized formulation designed to address hyperhidrosis and certain dermatological conditions. This semisolid gel is dispensed through a pump mechanism, ensuring easy and precise application on the skin, which is crucial for targeted treatment and optimal absorption of the active ingredients. The gel-like consistency allows for smooth application, forming a thin film over the affected area, which enhances the penetration and efficacy of the active compounds.

Aluminum Chloride Hexahydrate is a potent antiperspirant agent that works by temporarily blocking the sweat glands. When applied to the skin, it reacts with the electrolytes in sweat to form a gel-like plug within the sweat duct. This plug effectively reduces the flow of sweat to the skin surface, thereby managing excessive sweating, or hyperhidrosis. The high concentration of 40% in this formulation is particularly effective for individuals with severe hyperhidrosis, providing significant relief from excessive sweating and its associated discomfort.

Salicylic Acid, at a concentration of 4%, complements the action of Aluminum Chloride Hexahydrate by serving as a keratolytic agent. It works by softening and sloughing off the outer layer of the skin, which helps in the removal of dead skin cells and unclogging of pores. This action not only enhances the penetration of Aluminum Chloride Hexahydrate but also aids in the treatment of conditions like acne, psoriasis, and other hyperkeratotic skin disorders. By promoting exfoliation, Salicylic Acid helps in reducing the buildup of sweat and sebum, further contributing to the management of hyperhidrosis and improving overall skin texture.

The combination of these two active ingredients in a gel formulation offers a dual-action approach, addressing both excessive sweating and skin conditions that benefit from exfoliation and pore unclogging. The pump mechanism ensures that the right amount of gel is dispensed, minimizing waste and ensuring consistent application. This is particularly beneficial for patients who require precise dosing to manage their symptoms effectively.

For prescribers, this formulation provides a robust option for patients who have not responded to standard antiperspirant treatments or who require additional dermatological benefits. The high concentration of active ingredients necessitates careful patient selection and monitoring to ensure efficacy and minimize potential irritation. Patients should be advised to apply the gel to clean, dry skin, preferably at night, to maximize its effectiveness and reduce the risk of irritation.

If you have any questions or need further information about this formulation, please reach out to us at Bayview Pharmacy. Our team of compounding pharmacists is here to assist you with any inquiries or concerns you may have.

Other Uses

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The Aluminum Chloride Hexahydrate 40%/Salicylic Acid 4% Topical Gel, dispensed through a convenient pump mechanism, is primarily used for its antiperspirant and keratolytic properties. While it is commonly prescribed for conditions such as hyperhidrosis and certain dermatological disorders, this formulation may have other potential uses that could benefit both patients and prescribers. The combination of aluminum chloride hexahydrate and salicylic acid in a gel form allows for targeted application, which can be advantageous in managing localized skin conditions that require both moisture control and exfoliation.

Beyond its primary indications, this formulation may be considered for off-label use in managing conditions where excessive sweating and skin thickening are secondary concerns. For instance, patients with bromhidrosis, a condition characterized by unpleasant body odor due to bacterial breakdown of sweat, might find this gel beneficial. The aluminum chloride component can help reduce sweat production, thereby minimizing odor, while salicylic acid can assist in exfoliating the skin, reducing the buildup of keratin that can harbor bacteria.

Additionally, this gel may be useful in treating certain cases of keratosis pilaris, where the keratolytic action of salicylic acid can help smoothen the skin by removing excess keratin, and the aluminum chloride can help manage any associated sweating that might exacerbate the condition. Patients with plantar hyperkeratosis, a condition characterized by thickened skin on the soles of the feet, might also benefit from the dual action of this formulation, as it can help reduce both the thickness of the skin and any excessive moisture that can lead to discomfort or secondary infections.

For prescribers, considering the unique properties of this gel formulation can open up possibilities for addressing complex dermatological issues where moisture control and exfoliation are both desired outcomes. The pump mechanism ensures precise dosing, which is particularly important for patients who require consistent application to specific areas. As with any off-label use, it is essential to weigh the benefits against potential risks and to monitor patient outcomes closely.

If you have any questions or need further information about the potential uses of this formulation, please reach out to us at Bayview Pharmacy. Our team of compounding pharmacists is here to assist you with any inquiries or specific patient needs you may have.

Frequently Asked Questions

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What is Aluminum Chloride Hexahydrate 40%/Salicylic Acid 4% Topical Gel used for?

This topical gel is used for the treatment of excessive sweating (hyperhidrosis) and may also help in exfoliating the skin, reducing acne, and improving skin texture due to the presence of salicylic acid.

How do I apply the Aluminum Chloride Hexahydrate 40%/Salicylic Acid 4% Topical Gel?

Dispense a small amount of the gel using the pump mechanism and apply it to the affected area of the skin. Ensure the skin is clean and dry before application for optimal absorption.

How often should I use this topical gel?

Follow your healthcare provider's instructions regarding frequency of use. Typically, it may be applied once daily, preferably at night, to allow the active ingredients to work effectively while you sleep.

Can I use this gel on my face?

Consult with your healthcare provider before using this gel on your face, as the skin on the face can be more sensitive. If approved, apply sparingly and avoid contact with eyes and mucous membranes.

Are there any side effects associated with this gel?

Some users may experience skin irritation, redness, or dryness. If you experience severe irritation or an allergic reaction, discontinue use and consult your healthcare provider.

Can I use this gel if I am pregnant or breastfeeding?

Consult your healthcare provider before using this gel if you are pregnant or breastfeeding to ensure it is safe for you and your baby.

How should I store the Aluminum Chloride Hexahydrate 40%/Salicylic Acid 4% Topical Gel?

Store the gel at room temperature, away from direct sunlight and moisture. Keep it out of reach of children and pets.

Can I use this gel with other skincare products?

Consult your healthcare provider before combining this gel with other skincare products, especially those containing active ingredients, to avoid potential interactions or irritation.

What should I do if I miss a dose?

If you miss a dose, apply it as soon as you remember. If it is almost time for your next dose, skip the missed dose and resume your regular schedule. Do not double the dose to catch up.

Is this gel suitable for all skin types?

This gel may not be suitable for very sensitive skin due to its active ingredients. It is best to perform a patch test or consult with a healthcare provider to determine if it is appropriate for your skin type.

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Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.

No compounded medications are reviewed by the FDA for safety or efficacy.