Allopurinol 1.2 mg/mL Oral Suspension is a customized liquid formulation designed to provide an alternative dosing option for patients requiring allopurinol therapy. This suspension allows for precise dosing adjustments and is particularly beneficial for patients who have difficulty swallowing tablets or need doses that are not commercially available.

Allopurinol is a medication used to reduce the production of uric acid in the body by inhibiting the enzyme xanthine oxidase. It is commonly prescribed for the treatment of gout, hyperuricemia, and certain types of kidney stones. By lowering uric acid levels, allopurinol helps prevent the formation of urate crystals, relieving pain and inflammation associated with these conditions.

This oral suspension provides a homogeneous mixture where allopurinol is uniformly dispersed throughout the liquid medium, ensuring consistent dosing with each administration. It is especially useful for pediatric patients, elderly patients, or anyone who may have difficulty swallowing pills.

For patients, it is important to take this medication exactly as prescribed by your healthcare provider. Shake the bottle well before each use to ensure the medication is evenly distributed. Measure each dose carefully using a proper measuring device or syringe to ensure accuracy. Do not use household spoons, as they may not provide an accurate measurement.

For prescribers, this formulation offers flexibility in dosing, allowing for individualized therapy tailored to each patient's needs. It enables precise dose adjustments, which can be particularly important in managing conditions that require careful control of uric acid levels.

Potential side effects may include gastrointestinal upset, rash, or allergic reactions. It is important to monitor patients for any adverse effects, especially during the initial stages of therapy. Patients should be instructed to report any unusual symptoms or signs of hypersensitivity promptly.

Store the allopurinol oral suspension at room temperature, away from direct light and moisture. Ensure the bottle is tightly closed when not in use to maintain the stability of the medication.

If you have any questions or need additional information about this allopurinol oral suspension, please reach out to us. We are here to assist you with any concerns or inquiries you may have.

Allopurinol 1.2 mg/mL Oral Suspension is a liquid dosage form designed to provide a homogeneous mixture for administration, ensuring consistent dosing and ease of use, particularly for patients who may have difficulty swallowing tablets. Allopurinol is primarily used to treat conditions associated with excess uric acid in the body, such as gout and certain types of kidney stones. It works by inhibiting xanthine oxidase, an enzyme involved in the production of uric acid, thereby reducing uric acid levels in the blood and urine.

When considering the use of Allopurinol 1.2 mg/mL Oral Suspension, it is crucial to be aware of potential drug interactions that may affect the efficacy and safety of the treatment. Allopurinol can interact with a variety of medications, which may necessitate dosage adjustments or additional monitoring. One significant interaction is with azathioprine and mercaptopurine, as allopurinol can increase the levels of these drugs, leading to enhanced effects and potential toxicity. It is generally recommended to reduce the dose of azathioprine or mercaptopurine when used concurrently with allopurinol.

Another important interaction is with anticoagulants such as warfarin. Allopurinol may enhance the anticoagulant effect of warfarin, increasing the risk of bleeding. Patients on warfarin should have their INR levels closely monitored, and dose adjustments may be necessary. Additionally, allopurinol can interact with thiazide diuretics, potentially increasing the risk of hypersensitivity reactions, particularly in patients with renal impairment. It is advisable to monitor renal function and consider alternative diuretics if necessary.

Allopurinol may also interact with certain antibiotics, such as ampicillin and amoxicillin, increasing the risk of skin rashes. Patients should be advised to report any skin reactions promptly. Furthermore, the use of allopurinol with cyclosporine may increase cyclosporine levels, potentially leading to nephrotoxicity. Monitoring cyclosporine levels and renal function is recommended when these drugs are used together.

For patients and prescribers considering the use of Allopurinol 1.2 mg/mL Oral Suspension, it is essential to review the patient's current medication regimen to identify potential interactions. This will help in making informed decisions regarding the management of gout or other conditions associated with hyperuricemia. If you have any questions or require further information, please reach out to us for assistance.

Allopurinol 1.2 mg/mL Oral Suspension is a liquid dosage form designed to provide a precise and uniform delivery of allopurinol, an active pharmaceutical ingredient used primarily in the management of gout and certain types of kidney stones. This formulation is particularly beneficial for patients who have difficulty swallowing tablets or require tailored dosing adjustments, such as pediatric or geriatric patients. The suspension ensures that the medication is evenly distributed throughout the liquid medium, allowing for consistent dosing with each administration.

Allopurinol works by inhibiting the enzyme xanthine oxidase, which is responsible for the conversion of hypoxanthine and xanthine into uric acid. By reducing the production of uric acid, allopurinol helps to lower serum and urinary uric acid levels, thereby preventing the formation of uric acid crystals. This mechanism is crucial in the treatment of gout, a condition characterized by painful joint inflammation due to the deposition of uric acid crystals. Additionally, by decreasing uric acid levels, allopurinol can help prevent the formation of kidney stones in patients with hyperuricemia.

The oral suspension form of allopurinol offers several advantages. It allows for flexible dosing, which can be easily adjusted based on the patient's specific needs and response to therapy. This is particularly important in managing chronic conditions like gout, where long-term treatment is often necessary. The liquid form also facilitates easier administration for patients who may have difficulty with solid dosage forms, ensuring better adherence to the prescribed treatment regimen.

For prescribers, the allopurinol oral suspension provides an opportunity to customize treatment plans with precision, ensuring that patients receive the optimal dose to manage their condition effectively. It is important to monitor patients regularly to assess their response to therapy and adjust the dosage as needed. Patients should be advised to take the suspension as directed, and to shake the bottle well before each use to ensure the medication is properly mixed.

If you have any questions about this formulation or its use in treating specific disease states, please reach out to us at Bayview Pharmacy. Our team of compounding pharmacists is here to provide you with the information and support you need to ensure the best possible outcomes for your patients.

Allopurinol 1.2 mg/mL Oral Suspension is primarily used for the management of conditions associated with excess uric acid, such as gout and certain types of kidney stones. However, this formulation may have other potential uses that could benefit patients with specific medical needs. One such use is in the management of hyperuricemia associated with cancer therapy. Patients undergoing chemotherapy or radiation therapy for certain types of cancer may experience tumor lysis syndrome, a condition where rapid cell destruction leads to elevated uric acid levels. Allopurinol can help prevent or reduce the severity of this condition by inhibiting the production of uric acid, thereby protecting the kidneys and other organs from damage.

Additionally, allopurinol may be considered for use in patients with Lesch-Nyhan syndrome, a rare genetic disorder characterized by overproduction of uric acid. While not a cure, allopurinol can help manage the symptoms associated with this condition by reducing uric acid levels and preventing complications such as gouty arthritis and kidney stones. Furthermore, there is emerging interest in the potential role of allopurinol in cardiovascular health. Some studies suggest that allopurinol may have beneficial effects on endothelial function and may reduce the risk of cardiovascular events in patients with hyperuricemia, although more research is needed to fully understand these effects and establish appropriate guidelines for use.

For prescribers, it is important to consider the individual needs of each patient when determining the appropriateness of allopurinol for these alternative uses. Factors such as the patient's overall health, existing medical conditions, and concurrent medications should be taken into account to minimize the risk of adverse effects and drug interactions. Patients should be informed about the potential benefits and risks associated with allopurinol therapy, and regular monitoring of uric acid levels and renal function may be necessary to ensure safe and effective treatment.

If you have any questions or need further information about the use of Allopurinol 1.2 mg/mL Oral Suspension for these or other conditions, please reach out to us at Bayview Pharmacy. Our team of compounding pharmacists is here to assist you with any inquiries or concerns you may have.