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Formulas

Acyclovir 5%/Baclofen 2%/Clonidine HCl 0.2316%/Gabapentin 5%/Ketamine HCl 5.75%/Ketoprofen 10%/Lidocaine HCl 5% Topical Gel

This formulation is a compounded topical gel containing Acyclovir 5%, Baclofen 2%, Clonidine HCl 0.2316%, Gabapentin 5%, Ketamine HCl 5.75%, Ketoprofen 10%, and Lidocaine HCl 5%. It is a semisolid formulation dispensed through a pump mechanism, which allows for easy and precise application on the skin. The gel-like consistency ensures targeted treatment or absorption of the active ingredients.

The combination of these active ingredients is designed to treat a variety of disease states. Acyclovir is an antiviral medication used to treat infections caused by certain types of viruses. Baclofen is a muscle relaxer and an antispastic agent. Clonidine is used to treat high blood pressure, ADHD, and cancer pain. Gabapentin is used to treat nerve pain and seizures. Ketamine is used for starting and maintaining anesthesia. Ketoprofen is a nonsteroidal anti-inflammatory drug (NSAID) used to relieve pain, swelling, and joint stiffness. Lidocaine is a local anesthetic used to relieve pain and discomfort caused by skin irritations and minor burns.

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Acyclovir
Clonidine Hydrochloride
Gabapentin
Ketamine Hydrochloride
Ketoprofen
Lidocaine Hydrochloride
Baclofen
Topical Gel
652f53b0ebe233813a6901af
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Formula Information

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This formulation is a multi-ingredient topical gel that combines Acyclovir 5%, Baclofen 2%, Clonidine HCl 0.2316%, Gabapentin 5%, Ketamine HCl 5.75%, Ketoprofen 10%, and Lidocaine HCl 5%. It is designed to be dispensed through a pump mechanism, which allows for easy and precise application on the skin. The gel-like consistency ensures that the active ingredients are absorbed effectively into the skin for targeted treatment.

Acyclovir is an antiviral medication used to treat infections caused by certain types of viruses. In this formulation, it can help to reduce the pain and speed up the healing of sores or blisters in patients with herpes viruses. Baclofen is a muscle relaxer and an antispastic agent. It is used to treat muscle symptoms such as spasm, pain, and stiffness. Clonidine is primarily used to treat high blood pressure, but it can also provide relief from withdrawal symptoms associated with opioid addiction.

Gabapentin is an anticonvulsant and nerve pain medication, often used to treat seizures and pain caused by shingles. Ketamine is a powerful anesthetic that can provide pain relief. Ketoprofen is a nonsteroidal anti-inflammatory drug (NSAID) that can reduce inflammation and pain in the body. Lidocaine is a local anesthetic that works by causing temporary numbness/loss of feeling in the skin and mucous membranes. This can help to reduce pain or discomfort caused by minor skin irritations or procedures such as needle injections.

This formulation is designed to provide targeted relief from a variety of symptoms, including pain, inflammation, muscle stiffness, and certain types of viral infections. It is important to use this medication as directed by a healthcare professional. The combination of active ingredients allows for a multifaceted approach to symptom management, potentially increasing the effectiveness of treatment and improving patient comfort and quality of life.

If you have any questions about this formulation, please don't hesitate to reach out to us at Bayview Pharmacy. Our team of knowledgeable compounding pharmacists is always here to help.

Drug Interactions

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This topical gel formulation contains a combination of seven active ingredients: Acyclovir, Baclofen, Clonidine HCl, Gabapentin, Ketamine HCl, Ketoprofen, and Lidocaine HCl. Each of these ingredients has a specific therapeutic effect and they work together to provide relief from various disease states. However, it's important to be aware of potential drug interactions that may occur with this formulation.

Acyclovir is an antiviral medication used to treat viral infections. It may interact with other antiviral medications, potentially increasing the risk of side effects. If you are taking any other antiviral medications, please inform your healthcare provider.

Baclofen is a muscle relaxant and antispastic agent. It may interact with other central nervous system depressants, including alcohol, antihistamines, sedatives, and opioids, potentially leading to increased sedation and respiratory depression. Caution is advised when using these medications concurrently with this formulation.

Clonidine HCl is an antihypertensive agent that can interact with other antihypertensive drugs, leading to an additive effect and potentially causing a significant drop in blood pressure. It can also interact with CNS depressants, leading to increased sedation.

Gabapentin is an anticonvulsant and nerve pain medication. It may interact with antacids, reducing the absorption of gabapentin. It's recommended to take gabapentin at least 2 hours after taking an antacid. Gabapentin may also increase the effects of other CNS depressants, including opioids and alcohol.

Ketamine HCl is a general anesthetic. It may interact with other anesthetics, CNS depressants, and certain psychiatric medications, potentially leading to increased sedation, respiratory depression, and changes in blood pressure and heart rate.

Ketoprofen is a nonsteroidal anti-inflammatory drug (NSAID). It may interact with other NSAIDs, anticoagulants, and certain blood pressure medications, potentially increasing the risk of gastrointestinal bleeding and kidney damage.

Lidocaine HCl is a local anesthetic. It may interact with other local anesthetics and certain heart medications, potentially leading to increased risk of side effects such as irregular heart rhythm.

It's important to inform your healthcare provider of all medications you are currently taking, including prescription drugs, over-the-counter medications, and dietary supplements. This will help to prevent potential drug interactions and ensure the safe and effective use of this formulation.

If you have any questions or concerns about this formulation or potential drug interactions, please don't hesitate to reach out to us. We are here to help and provide you with the information you need to make informed decisions about your healthcare.

How Does it Work

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This topical gel formulation combines several active ingredients, each with a unique mechanism of action, to provide comprehensive pain relief and antiviral activity. The gel is designed to be easily applied to the skin, where it can be absorbed to target specific areas of discomfort or infection.

Acyclovir, an antiviral medication, works by slowing the growth and spread of the herpes virus in the body. It interferes with the virus's ability to replicate and infect new cells, helping to control symptoms of viral infections.

Baclofen is a muscle relaxer and an antispastic agent. It works by restoring the normal transmission of nerve signals in certain parts of the body, thereby reducing pain and muscle stiffness.

Clonidine HCl is an alpha-2 adrenergic agonist that works by stimulating receptors in the brain that reduce the transmission of pain signals through the nervous system. This can help to alleviate discomfort associated with certain conditions.

Gabapentin is an anticonvulsant and nerve pain medication. It works by affecting the chemicals and nerves in the body that are involved in the cause of seizures and some types of pain.

Ketamine HCl is a powerful anesthetic that provides pain relief by blocking the NMDA receptor, a type of glutamate receptor, in the brain and spinal cord. This prevents the transmission of pain signals to the brain.

Ketoprofen is a nonsteroidal anti-inflammatory drug (NSAID) that works by reducing hormones that cause inflammation and pain in the body.

Lidocaine HCl is a local anesthetic that works by blocking nerve signals in your body. It is used to reduce pain or discomfort caused by skin irritations.

Together, these ingredients work synergistically to provide comprehensive pain relief and antiviral activity. The gel formulation allows for targeted application and absorption, ensuring that the active ingredients are delivered directly to the area where they are needed most.

If you have any questions about this formulation or how it works, please don't hesitate to reach out to us at Bayview Pharmacy. Our team of compounding pharmacists is always here to help.

Other Uses

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This complex topical gel primarily serves as a treatment for a variety of pain syndromes that include neuropathic pain, post-herpetic neuralgia, and complex regional pain syndrome. These conditions often require a multi-modal approach to management, which explains the presence of multiple active ingredients each with different but complementary mechanisms of action. In addition, this formulation is designed to offer targeted relief at the site of application, rather than systemic effects.

However, beyond these conditions, there may be other potential uses for this formulation. For instance, due to the presence of lidocaine, a topical anesthetic, this gel could be utilized as temporary relief for other sources of localized pain such as minor burns, insect bites, and skin irritations. Note, though, that the gel should only be applied on intact skin and not on open wounds or mucous membranes.

Moreover, given the antiviral properties of acyclovir, this formulation may also provide some benefits in managing certain forms of cutaneous viral infections like recurrent herpes simplex virus (HSV) infections. This might offer a localized alternative for patients who have poor tolerance to systemic antiviral therapy.

The anti-inflammatory effect of Ketoprofen, combined with the local anesthetic Lidocaine, may also make this gel an option for relieving symptoms associated with certain dermatological conditions like contact dermatitis, although further research may be necessary to fully establish its effectiveness for this purpose.

It is critical for patients and prescribers to note that the "other uses" listed are potential uses and may not have been as thoroughly researched or approved by regulatory bodies in comparison to the initial indicated uses. As such, off-label use should always be conducted under the supervision of a competent healthcare professional familiar with the medication's properties and with a full understanding of the patient's medical history and current condition. Always consult with your healthcare provider before using this formulation for any uses other than those explicitly prescribed.

If you have any questions about this complex topical gel, or if you are interested in exploring its potential uses further, please do not hesitate to reach out to us. We are a knowledgeable team of compounding pharmacists and are here to assist you in any way possible.

Frequently Asked Questions

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What is this compounded formulation used for?

This compounded formulation is used to manage and alleviate symptoms related to a variety of conditions such as nerve pain, muscle spasms, and inflammation. It is applied topically to the skin for targeted treatment.

How do I use this medication?

This medication is presented as a semisolid formulation dispensed through a pump mechanism. Apply it on clean, dry skin over the affected area as instructed by your healthcare provider. It is designed for easy and precise application.

Does this treatment have any side effects?

As with all medications, there could be potential side effects. You may experience some skin irritation or mild discomfort at the application site. However, the risk of systemic side effects is generally lower with topical medications. If you notice any severe or persistent side effects, please inform your healthcare provider.

What is the consistency of this compound formulation?

The compound formulation has a gel-like consistency, which allows it to be easily spread over the skin and facilitate absorption of the active ingredients.

What does the percentage denote in each ingredient?

The percentage indicates the concentration of each ingredient in the final compound. For example, Acyclovir 5% means that there is 5g of Acyclovir in 100g of the final gel formulation.

What is the role of each component in this formulation?

Each component contributes to the overall effectiveness of the formulation. Acyclovir is an antiviral agent, Baclofen and Clonidine are muscle relaxants, Gabapentin is used for nerve pain, Ketamine is an anaesthetic, Ketoprofen is a non-steroidal anti-inflammatory drug, and Lidocaine is a local anesthetic.

Can I use it with other topical treatments?

Before combining treatments, consult with your healthcare provider. Different products may interfere with each other, affect absorption, or increase the risk of side effects.

Can I use it on broken skin?

Please avoid applying the gel on broken or irritated skin unless directed otherwise by your healthcare provider, as this can potentially increase risk of unwanted side effects.

Is there a specific way to store this medication?

Store the medication in a cool, dry place away from direct sunlight. Always refer to the product label for specific storage instructions.

Is this medication prescription-only?

Yes, this compounding formulation is available only through prescription by a licensed healthcare provider. Always follow their instructions for use.

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Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.

No compounded medications are reviewed by the FDA for safety or efficacy.