This formulation is a rectal suppository containing Acetaminophen 130 mg and Codeine Phosphate 13 mg. Acetaminophen is a pain reliever and a fever reducer, while Codeine Phosphate is a narcotic pain reliever. The combination of these two active ingredients provides effective relief from moderate to severe pain. The suppository form allows for the medication to be absorbed directly into the bloodstream through the rectal tissue, providing faster relief than oral administration.

Acetaminophen works by changing the way the body senses pain and by cooling the body. Codeine, on the other hand, works in the brain to change how your body feels and responds to pain. This combination medication is typically used to relieve pain, coughing, and fever associated with conditions such as influenza, common cold, or after surgery or dental procedures. It may also be used for other conditions as determined by your healthcare provider.

It's important to note that this medication should be used only as directed by your healthcare provider. Overuse or misuse can lead to addiction, overdose, or death, especially in a child or other person using the medicine without a prescription. Also, while using this product, do not use any other drug containing acetaminophen without asking your doctor or pharmacist first. Acetaminophen is in many nonprescription and prescription medications (such as pain/fever drugs or cough-and-cold products). Too much acetaminophen may cause liver damage.

Patients should also be aware of potential side effects, which may include dizziness, lightheadedness, nausea, vomiting, shortness of breath, and sweating. If any of these effects persist or worsen, tell your doctor or pharmacist promptly. To prevent constipation, eat dietary fiber, drink enough water, and exercise. You may also need to take a laxative. Ask your pharmacist which type of laxative is right for you.

For prescribers, it's important to consider the patient's overall health status, other medications they may be taking, and their history of drug use or addiction. This medication should be prescribed with caution in patients with a history of drug abuse or addiction, as it can be habit-forming. Regular monitoring of the patient's response to the medication and any potential side effects is recommended.

If you have any questions about this formulation, please don't hesitate to reach out to us at Bayview Pharmacy. Our team of knowledgeable compounding pharmacists is here to assist you.

The combination of Acetaminophen and Codeine Phosphate in a rectal suppository form is used to relieve moderate to severe pain. Acetaminophen is a non-opioid pain reliever that works by increasing the pain threshold, while Codeine Phosphate is an opioid pain reliever that works by changing the way the brain and nervous system respond to pain.

It's important to be aware of potential drug interactions when using this formulation. Certain medications may affect how Acetaminophen and Codeine Phosphate work or increase your risk for serious side effects.

Some drugs that may interact with this formulation include: other opioid pain or cough relievers (such as morphine, hydrocodone), alcohol, marijuana, drugs for sleep or anxiety (such as alprazolam, lorazepam, zolpidem), muscle relaxants (such as carisoprodol, cyclobenzaprine), or antihistamines (such as cetirizine, diphenhydramine).

Check the labels on all your medicines (such as allergy or cough-and-cold products) because they may contain ingredients that cause drowsiness or increase the risk of liver damage. Ask your pharmacist about using those products safely.

Other medications can affect the removal of codeine/acetaminophen from your body, which may affect how this product works. Examples include azole antifungals (such as ketoconazole), macrolide antibiotics (such as erythromycin), HIV medications (such as ritonavir), rifamycins (such as rifabutin, rifampin), certain drugs used to treat seizures (such as carbamazepine, phenytoin), among others.

This medication may interfere with certain laboratory tests (including amylase/lipase levels), possibly causing false test results. Make sure laboratory personnel and all your doctors know you use this drug.

Do not start, stop, or change the dosage of any medicines without your doctor's approval. A product that may interact with this drug is: metoclopramide.

Remember that this medication has been prescribed because your doctor has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist. If you have any questions or concerns about this medication, please reach out to us at Bayview Pharmacy. We are here to help.

The Acetaminophen 130 mg/Codeine Phosphate 13 mg Rectal Suppository is a solid dosage form that is designed to be inserted into the rectum. Once inserted, the suppository dissolves or melts due to the body's natural heat, releasing the active ingredients, Acetaminophen and Codeine Phosphate, into the surrounding tissues.

Acetaminophen, also known as Paracetamol, is a common over-the-counter medication used to relieve pain and reduce fever. It works by inhibiting the production of prostaglandins, substances in the body that cause pain and inflammation. By reducing the levels of these substances, Acetaminophen can effectively alleviate pain and lower fever.

Codeine Phosphate, on the other hand, is an opioid analgesic. It works by binding to opioid receptors in the brain and spinal cord, blocking the transmission of pain signals to the brain. This results in a decrease in the perception of pain.

The combination of Acetaminophen and Codeine Phosphate in this suppository formulation provides a dual-action approach to pain management. While Acetaminophen works to reduce pain at the source, Codeine Phosphate alters the perception of pain at the central nervous system level. This combination can provide effective relief for moderate to severe pain.

Furthermore, the rectal administration route offers several advantages. It allows for medication to be administered when oral intake is not possible or desirable, such as in cases of nausea or vomiting. It also bypasses the first-pass metabolism in the liver, which can lead to a more rapid and efficient absorption of the medication. This can result in quicker onset of pain relief.

This formulation can be used to treat various disease states that involve pain and inflammation, such as post-surgical pain, cancer pain, and pain from injuries. It can also be used to manage conditions with intermittent or chronic pain, such as arthritis or fibromyalgia.

As with any medication, it is important to use this formulation as directed by a healthcare provider. Potential side effects can include constipation, nausea, dizziness, and drowsiness. It is also important to note that Codeine Phosphate has the potential for addiction and should be used with caution.

If you have any questions about the Acetaminophen 130 mg/Codeine Phosphate 13 mg Rectal Suppository, or if you would like more information about its use and potential side effects, please do not hesitate to reach out to us at Bayview Pharmacy. Our team of knowledgeable compounding pharmacists is always here to help.

In addition to the known uses as a pain reliever, Acetaminophen 130 mg/Codeine Phosphate 13 mg Rectal Suppositories may be employed in other unique circumstances under the guidance of a healthcare professional. This dual active agent suppository can be administered when oral medication may be difficult or contraindicated, such as for patients who have difficulty swallowing tablets or liquids, those with vomiting or nausea, or when immediate absorption is needed.

While both agents are potent analgesics, they also have additional properties which may provide relief in certain scenarios. Acetaminophen is also an antipyretic, meaning it can be used to reduce fever, which can be beneficial in situations where a high temperature is causing discomfort. Codeine phosphate, as an opioid component, may also be used to induce drowsiness, produce calmness and to inhibit coughing reflex. Hence, it may be effectively used for symptomatic relief of non-productive cough, and in certain sleep disorders under certain circumstances.

Moreover, this formulation can be utilized in palliative care settings, or when ease of administration and rapid onset is required; for example, in the management of severe pain related to surgical procedures or traumatic injuries. However, the use for enhanced sleep induction and cough suppression must be done under careful supervision owing to the potential for misuse and dependency associated with codeine.

Prescribers should note that the utilization of this formulation beyond the approved indications should be based on careful risk-benefit evaluation, considering the potential for side effects, including constipation, respiratory distress, and the risk of opioid addiction. Patient-specific factors such as age, overall health status, concurrent medications, and the potential for interactions should also be taken into account before prescribing this medication for off-label uses. It's also important to understand that individual response to medication can vary, and dosage may need to be adjusted accordingly.

If you have any further questions or need more information, please don't hesitate to reach out to us at Bayview Pharmacy. Our team of knowledgeable compounding pharmacists is here to provide you with all the information you need in your decision to use this specific formulation.