Sorbitol is a versatile polyol (sugar alcohol) commonly used in pharmaceutical formulations for its humectant, sweetening, and stabilizing properties. It is often utilized in compounded medications to enhance the palatability and texture of oral solutions and suspensions, making them more acceptable for patients, especially children and those with difficulty swallowing.
In addition to its role as a sweetener, sorbitol acts as an osmotic laxative, which can be beneficial in formulations aimed at alleviating constipation. Its non-cariogenic nature makes it a preferred choice in formulations where dental health is a concern. Sorbitol's compatibility with a wide range of active ingredients and excipients further underscores its importance in pharmaceutical compounding.
Sorbitol is a versatile polyol (sugar alcohol) commonly used in pharmaceutical formulations for its sweetening and humectant properties. It is often utilized in compounded medications to enhance palatability, especially in oral liquid preparations, making them more acceptable to patients, particularly children and those with difficulty swallowing tablets.
In addition to its sweetening capabilities, sorbitol acts as a stabilizer and thickening agent, contributing to the overall texture and consistency of formulations. Its non-cariogenic nature makes it a preferred choice in formulations where dental health is a concern, as it does not contribute to tooth decay.
Sorbitol is also known for its osmotic laxative properties, which can be beneficial in formulations aimed at alleviating constipation. This characteristic is due to its ability to draw water into the large intestine, promoting bowel movements. However, it is important for prescribers to consider the potential for gastrointestinal discomfort in sensitive individuals when recommending sorbitol-containing products.
Furthermore, sorbitol is metabolized slowly by the body, making it a suitable ingredient for diabetic patients as it has a lower impact on blood glucose levels compared to regular sugars. This makes it an ideal component in formulations designed for patients requiring sugar-free or low-sugar options.