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Fluocinonide is a potent topical corticosteroid widely used in dermatology for its anti-inflammatory, antipruritic, and vasoconstrictive properties.
Fluocinonide is a synthetic corticosteroid used in dermatology for its anti-inflammatory, antipruritic, and vasoconstrictive properties.[2][1] It is prescribed for various skin conditions, including eczema and psoriasis, where it helps reduce inflammation, itching, and redness.[1]
Fluocinonide is classed as a high-potency (0.05%) or superpotent (0.1%) topical corticosteroid.[2] Topical corticosteroids act through vasoconstriction, inhibition of phospholipase A2 release, and direct inhibition of inflammatory transcription factors, along with immunosuppressive effects in the skin.[2]
Fluocinonide is applied topically, and its use should be monitored by healthcare professionals to minimize potential side effects. Skin atrophy (thinning) is the most common adverse effect of topical corticosteroids, and systemic absorption with HPA axis suppression is more likely with prolonged use, application over large areas, and occlusive dressings.[2] Prescribers should consider potency and strength when recommending fluocinonide, matching it to the severity and site of the condition being treated.[2]
Fluocinonide is available in ointment, cream, solution, and gel forms.[1] Bayview Pharmacy compounds fluocinonide preparations on a prescriber's order.
Compounded at Bayview
Patient guides for the preparations we make most often. Each one is compounded to order and requires a prescription.
For prescribers
Every preparation in our formulary that contains this ingredient. Strength, base and dose form are set by the prescription.
Fluocinonide is a high-potency corticosteroid used on the skin for inflammatory conditions such as eczema, psoriasis, and lichen planus. Manufactured fluocinonide comes as 0.05% cream, ointment, gel, and solution and as a 0.1% cream. Bayview compounds it when your prescriber wants a different strength, a different base, or an oral paste or rinse for the inside of the mouth. The compounded preparations are not FDA-approved and are prepared to your prescriber's order.
Skin conditions that respond to corticosteroids: eczema and atopic dermatitis, plaque psoriasis, contact dermatitis, lichen planus, discoid lupus, and similar inflammatory rashes, usually on thicker skin such as the arms, legs, trunk, hands, feet, and scalp. The oral adhesive paste and rinse are prescribed for lichen planus and other sore, inflamed patches inside the mouth. Your prescriber decides whether it is appropriate for you and at what strength.
Most are local: burning or stinging when applied, itching, dryness, redness, acne-like bumps, and lightening of the skin. Used for too long, on thin skin, or under a covering, potent steroids can thin the skin, cause stretch marks and visible blood vessels, and be absorbed in amounts that affect the body's own steroid production, which can show up as unusual tiredness, weight gain, a rounded face, or muscle weakness. Children absorb more through their skin and can have slowed growth. Inside the mouth, the usual problem is thrush. Contact your prescriber if any of these happen.
Not unless your prescriber specifically directs it. Facial skin, the groin, underarms, and skin folds are thin and absorb more steroid, so they are more likely to be damaged by a high-potency product; prescribers usually choose a milder steroid or a steroid-sparing option such as compounded tacrolimus for those areas. Children absorb proportionally more steroid than adults, so fluocinonide is used in children only under a pediatric prescriber's direction, at the lowest strength for the shortest time, and never under a diaper or plastic pants.
Compounded fluocinonide starts at $98 for 15 g, and the price varies with the strength, base, and size. Where a manufactured fluocinonide product fits your prescriber's order, that is what we dispense and it may cost less — compounding is for the strengths, bases, and oral forms no manufacturer makes. Compounded preparations are cash-priced and are generally eligible for HSA and FSA cards. Call us at 401-284-4505 with the preparation and quantity your prescriber ordered and we will quote it before we make it.
Other salt forms of this molecule, and ingredients commonly compounded alongside it.
This page describes an active pharmaceutical ingredient, not a finished drug product. Bayview Pharmacy compounds preparations containing it only on a prescriber's order for an individual patient.
Compounded preparations are not FDA-approved, and the FDA has not evaluated them for safety, effectiveness, or manufacturing quality. Nothing on this page is a claim that any preparation is effective for any condition.
A valid prescription is required. Availability depends on Bayview's licensure in your state. This page is general information, not medical advice — discuss your situation with a licensed healthcare provider.
Our pharmacists work with prescribers to build preparations around a patient's dose, form and tolerances. Ask us what is possible with this ingredient.
