Calcipotriene is a synthetic derivative of calcitriol, a form of vitamin D, and is primarily used in the treatment of psoriasis. It functions by modulating the growth and differentiation of skin cells, thereby reducing the excessive proliferation characteristic of psoriatic lesions. This mechanism of action makes calcipotriene an effective option for managing mild to moderate plaque psoriasis, often resulting in significant improvement in the appearance of the skin.

In addition to its efficacy, calcipotriene is generally well-tolerated, with a favorable safety profile when used as directed. Common side effects may include mild skin irritation, such as redness or itching, which typically resolve with continued use. It is important for prescribers to consider the potential for hypercalcemia, although this is rare and usually associated with excessive use.

Calcipotriene is often compounded into various formulations to enhance its application and effectiveness, tailored to meet specific patient needs. These formulations can be customized to optimize the delivery and absorption of the active ingredient, ensuring that patients receive the most benefit from their treatment regimen. By understanding the pharmacological properties and clinical applications of calcipotriene, healthcare providers can make informed decisions when prescribing this medication for their patients.