Sulfanilamide 15% Vaginal Cream is a semisolid formulation specifically compounded to combat gynecological infections. This cream is designed to be applied directly to the vaginal area, ensuring targeted delivery of the active ingredient, sulfanilamide. The medication is dispensed in a tube, which allows for convenient, hygienic, and precise application. Sulfanilamide, the active component, is a sulfa drug that exhibits bacteriostatic properties by inhibiting the synthesis of folic acid in bacteria, which is essential for their growth and replication. This mechanism of action makes it effective against a broad spectrum of gram-positive and gram-negative organisms.

The 15% concentration of sulfanilamide in the cream is specifically chosen to provide an optimal balance between efficacy and tolerability. This formulation is commonly used to treat vaginal infections such as bacterial vaginosis, and other infections caused by susceptible organisms. It can alleviate symptoms like itching, burning, and discharge by eradicating the causative bacteria. The cream base also provides a soothing effect, which can help to relieve local irritation and discomfort associated with the infection.

For patients, it is important to follow the prescribed regimen closely to achieve the best therapeutic outcomes. The cream should be applied as directed by the healthcare provider, usually once or twice daily for a specified duration. It is also crucial to complete the full course of treatment to prevent the recurrence of infection and the development of antibiotic resistance. Patients should be advised of potential side effects, which may include local irritation or allergic reactions, and instructed to contact their healthcare provider if they experience any adverse effects.

Prescribers should consider the patient's medical history, including any known allergies to sulfa drugs or other components of the cream, before recommending this formulation. Additionally, prescribers should monitor the patient's progress and adjust treatment as necessary based on the response to therapy and any side effects encountered.

At Bayview Pharmacy, we are committed to providing high-quality compounded medications tailored to the specific needs of our patients. Our team of knowledgeable compounding pharmacists is available to answer any questions and provide guidance on the use of Sulfanilamide 15% Vaginal Cream. If you have any questions or require further information about this formulation, please do not hesitate to reach out to us.

Sulfanilamide, a sulfonamide antibiotic, works by inhibiting the growth of bacteria in the vagina, thereby treating bacterial infections that can cause various gynecological conditions. When considering the use of sulfanilamide 15% vaginal cream, it is important to be aware of potential drug interactions that may affect the efficacy of the treatment or cause adverse effects.

One key interaction is with methenamine, a medication used to treat urinary tract infections. Sulfanilamide may reduce the effectiveness of methenamine by preventing its conversion to formaldehyde, which is necessary for its antibacterial action. Therefore, concurrent use of these medications should be avoided or closely monitored by a healthcare provider.

Patients should also be cautious when using sulfanilamide with anticoagulants such as warfarin. Sulfonamides can potentiate the effects of warfarin, increasing the risk of bleeding. If these medications must be used together, close monitoring of prothrombin time or international normalized ratio (INR) is recommended, and dosage adjustments may be necessary.

Additionally, sulfanilamide may interact with oral hypoglycemic agents, such as sulfonylureas, which are used to control blood sugar levels in patients with diabetes. The hypoglycemic effect of these agents can be enhanced when used with sulfonamides, leading to an increased risk of hypoglycemia. Patients should monitor their blood glucose levels regularly, and dosage adjustments of the hypoglycemic agent may be required.

Another consideration is the concurrent use of sulfanilamide with other local vaginal products. The combination of multiple vaginal products may alter the pH of the vagina or cause an imbalance in the natural flora, which could reduce the effectiveness of sulfanilamide or lead to irritation. It is advisable to consult a healthcare provider before combining treatments.

It is also important to note that sulfanilamide may interfere with certain laboratory tests, including urine glucose tests that use Benedict's reagent or Fehling's solution. Informing the laboratory personnel or your healthcare provider about the use of sulfanilamide is crucial to avoid misinterpretation of test results.

Patients should always inform their healthcare provider of all medications, supplements, and herbal products they are currently taking before starting treatment with sulfanilamide 15% vaginal cream. This includes prescription drugs, over-the-counter medications, and any other topical treatments applied to the vaginal area. By doing so, the healthcare provider can assess for potential drug interactions and make appropriate recommendations to ensure safe and effective use of the medication.

If you have any questions or concerns regarding the use of sulfanilamide 15% vaginal cream or potential drug interactions, please reach out to us at Bayview Pharmacy. Our team of compounding pharmacists is here to provide you with the information and support you need to manage your gynecological health safely and effectively.

Sulfanilamide 15% Vaginal Cream is a semisolid formulation that is specifically designed to combat bacterial infections in the vaginal area. The active ingredient, sulfanilamide, belongs to a class of drugs known as sulfonamides, which act by inhibiting the growth and multiplication of bacteria. When applied to the affected area, sulfanilamide interferes with the bacteria's ability to produce folic acid, an essential component for bacterial growth and cell division. Without folic acid, the bacteria cannot replicate or repair themselves, leading to a decrease in the bacterial population and alleviation of the infection.

The cream is dispensed in a tube, which allows for convenient and precise application. This is particularly important for delivering the medication directly to the site of infection, ensuring maximum effectiveness. The formulation is designed to maintain contact with the vaginal mucosa, providing a sustained release of the active ingredient over time. This prolonged exposure is crucial for ensuring that the medication remains at the site of infection in therapeutic concentrations long enough to exert its full antibacterial effect.

By treating the underlying bacterial infection, Sulfanilamide 15% Vaginal Cream helps to alleviate symptoms associated with specific gynecological conditions such as vaginitis and vulvovaginitis. These conditions can be caused by various bacteria that are sensitive to sulfanilamide. The cream can reduce symptoms such as itching, burning, discharge, and discomfort, improving the overall quality of life for the patient.

It is important for both patients and prescribers to understand that while Sulfanilamide 15% Vaginal Cream is effective against certain bacteria, it is not effective against all types of vaginal infections, such as those caused by fungi or viruses. Therefore, proper diagnosis is essential before starting treatment with this medication. Additionally, patients should be advised to complete the full course of treatment, even if symptoms improve before the medication is finished, to prevent the recurrence of infection and the development of antibiotic resistance.

For any questions regarding the use of Sulfanilamide 15% Vaginal Cream, its mechanism of action, or its suitability for treating specific gynecological conditions, please reach out to us at Bayview Pharmacy. Our team of compounding pharmacists is here to provide the necessary information and support to ensure safe and effective treatment for our patients.

The Sulfanilamide 15% Vaginal Cream is primarily formulated to provide treatment for specific gynecological conditions, such as bacterial vaginosis and certain vulvar skin conditions. However, beyond these primary uses, the formulation can be employed for its potential off-label benefits. Patients may find relief from other types of vaginal infections due to sulfanilamide's broad antibacterial properties. It is also worthwhile to note that while the cream is specifically designed for vaginal application, some practitioners have explored its efficacy in treating other skin infections that are responsive to sulfonamides, given the general antimicrobial activity of sulfanilamide. Nonetheless, such uses should only be considered following a thorough evaluation and under the guidance of a healthcare provider to ensure safety and appropriate treatment.

Please be aware that the excipients in the cream are chosen for compatibility with the vaginal environment; use in other areas or on different skin conditions should be approached with caution, as the safety and efficacy profiles may not be established for those uses. Moreover, before considering this formulation for alternative applications, it is crucial to account for potential sensitivities or contraindications that may arise from the active ingredient or auxiliary components in the formulation.

It is vital for both patients and prescribers to acknowledge that while sulfanilamide has historical use in a wide range of bacterial infections, antibiotic resistance and the development of newer, more targeted therapies have made such traditional uses less common. In the modern clinical setting, the use of sulfanilamide, particularly in a cream formulation, is typically limited to specific indications where it has been proven effective and safe through clinical research and practice.

For prescribers considering this formulation for alternative therapeutic applications, a comprehensive review of the patient’s medical history, current medications, and known allergies is recommended. Additionally, prescribers should monitor patients for any adverse effects and assess the efficacy of the formulation for the intended use. Informing the patient about the nature of off-label use and obtaining informed consent is also an important part of the prescribing process.

If you have questions about the indications, contraindications, potential alternative uses, or specific concerns regarding Sulfanilamide 15% Vaginal Cream, please do not hesitate to reach out to us at Bayview Pharmacy. Our team of compounding pharmacists can provide further information and consultation to ensure the safe and effective use of this formulation for your patients.