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Propranolol Hydrochloride 20 mg/mL Sublingual Solution

FDA-approved generic
Dose form
Sublingual Solution
Active ingredients
Propranolol Hydrochloride
For prescribers
Prescription details
RxThis formula
Dose formSee below
Quantity____
SigAs directed by prescriber
Refills____
PharmacyBayview Pharmacy, Warwick RI, NCPDP 4106882
Copy prescription detailsOrder form
Controlled substance: e-prescribe (EPCS) from your EHR. Faxed and phoned prescriptions cannot be accepted for this preparation.
Send it from your EHR, or fax to (401) 284-4506. How to e-prescribe this formula
Licensed to fill prescriptions for patients in RI, MA, CT, NJ, NH, FL, ME and PA. New York patients are served on a limited basis while nonresident registration is pending.
To prescribe, you must be a verified prescriber.
To prescribe, you must be in a state where we hold an active out-of-state pharmacy license.
Starting at
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Requires a prescription from your own provider. Bayview is a pharmacy and does not prescribe.
Ships within 1 to 2 business days after pharmacist verification
HSA and FSA eligible
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Get a one-page sheet with everything your doctor needs to prescribe this and send it to Bayview.

Licensed to fill prescriptions for patients in RI, MA, CT, NJ, NH, FL, ME and PA. New York patients are served on a limited basis while nonresident registration is pending.

For prescribersSign in for prescription details and order forms.
Compounded preparations are prepared by Bayview pursuant to a prescription for an individual patient. They are not FDA-approved and have not been evaluated by FDA for safety or effectiveness.
Propranolol Hydrochloride
Sublingual Solution
66fd7b0bdc31c32733aec9f2
Service area

Can we ship this formula to your state?

Bayview fills prescriptions for patients in Connecticut, Florida, Maine, Massachusetts, New Hampshire, New Jersey, Pennsylvania and Rhode Island. New York patients are served on a limited basis while nonresident pharmacy registration is pending.

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Available in

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Our current service area

Currently licensed Limited basis, registration pending Not available for this formula Not currently licensed

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Prepared to a prescriber's order for one patient. Not FDA-approved.

This formulation

This is a compounded sublingual solution containing propranolol hydrochloride, prepared to a prescriber's order for one patient. Compounded preparations are not FDA-approved.

FDA product listings

These listings cover every salt or ester form of each drug in the FDA National Drug Code Directory.

FDA-approved products containing propranolol are listed in solution, tablet, capsule and injection forms.

Storage category and dating

Liquid bases can be aqueous or nonaqueous, and USP <795> classifies the preparation by its water activity. Aqueous preparations carry shorter default beyond-use dates than nonaqueous ones. The date printed on the label is the one to follow.

Sources

Propranolol is a nonselective beta-blocker that compounding pharmacies prepare as oral liquids, capsules and topical creams or gels by prescription.

About this ingredient

Propranolol is a beta-blocker. It blocks both beta-1 and beta-2 adrenergic receptors, which slows the heart rate, lowers the force of each heartbeat and blunts the body's response to adrenaline. Manufactured forms include tablets, extended-release capsules, an oral solution and an injection. Inderal LA extended-release capsules are FDA-approved for high blood pressure, angina from coronary artery disease, prevention of common migraine and hypertrophic subaortic stenosis. Hemangeol oral solution is approved for proliferating infantile hemangioma requiring systemic therapy. No manufactured topical form of propranolol exists, so a prescriber may order it compounded as a cream or gel, or as an oral liquid or capsule in a strength or vehicle not made commercially. Compounded preparations are not FDA-approved and require a prescription.

Safety and interactions

Propranolol does not carry a boxed warning, but the label warns that stopping it suddenly has led to worsening angina and, in some cases, heart attack, so do not stop it suddenly. Do not use propranolol if you have cardiogenic shock, a very slow heart rate or heart block beyond first degree without a pacemaker, bronchial asthma, or an allergy to propranolol. It can mask signs of low blood sugar and an overactive thyroid, may worsen heart failure, and can make epinephrine less able to treat a severe allergic reaction. Drugs that block CYP2D6, CYP1A2 or CYP2C19 can raise propranolol levels, and warfarin needs closer monitoring. Newborns exposed near delivery may have a slow heart rate, low blood sugar or breathing problems. Propranolol passes into breast milk in small amounts, and LactMed says no special precautions are required. For dizziness, fatigue or breathing trouble, talk to your prescriber or pharmacist.

Propranolol is a nonselective, competitive beta-adrenergic antagonist and class II antiarrhythmic with membrane-stabilizing activity. It is highly lipid soluble and crosses the blood-brain barrier and placenta. Oral absorption is nearly complete, but extensive first-pass hepatic metabolism leaves systemic bioavailability around 20 to 30 percent; about 90 percent is bound to albumin and alpha-1-acid glycoprotein. It is metabolized mainly by CYP2D6 and CYP1A2, with a lesser CYP2C19 role, and is a P-glycoprotein substrate. Half-life is about 3 to 6 hours for immediate-release forms and about 10 hours for Inderal LA. Labeled indications include hypertension, angina, migraine prophylaxis and hypertrophic subaortic stenosis (Inderal LA) and proliferating infantile hemangioma (Hemangeol). Prescribers have ordered compounded topical propranolol for superficial infantile hemangioma; a 2025 formulation study notes no commercial topical product exists, so pharmacies prepare it extemporaneously. Dosing per prescriber. Monitor heart rate, blood pressure and glucose in patients with diabetes, and taper rather than stop abruptly. Propranolol is not a controlled substance.

Sources

Using and storing

How it is used

Draw up the dose with the oral syringe or dropper provided. Squirt or drop it under your tongue and hold it there without swallowing for the time on your label. Swallow afterward. Avoid eating or drinking for about 30 minutes after the dose unless your pharmacist says otherwise.

Storing it

Sublingual solutions are aqueous. Under USP <795>, a preserved solution usually carries a beyond-use date of up to 35 days at room temperature or refrigerated, and an unpreserved one 14 days refrigerated. Your label shows whether to refrigerate and the beyond-use date. Keep out of reach of children and discard after that date.

Sources

Prescribing and ordering FAQs

Formula Information

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Drug Interactions

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How Does it Work

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Frequently Asked Questions

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About this compounded preparation

This formulation is compounded by Bayview Pharmacy on a prescriber's order for an individual patient. It is not an FDA-approved drug product, and the FDA has not evaluated it for safety, effectiveness, or manufacturing quality.

A valid prescription is required. Availability depends on Bayview's licensure in your state. This page is general information, not medical advice. Discuss your situation with a licensed healthcare provider.

Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.

No compounded medications are reviewed by the FDA for safety or efficacy.
For prescribers

How to e-prescribe this formula

Controlled substance: e-prescribe only (EPCS). Faxed, phoned, and handwritten prescriptions cannot be filled. Rhode Island law (R.I. Gen. Laws § 21-28-3.18) requires Schedule II to V prescriptions to be transmitted electronically.
1

Find Bayview in your EHR's pharmacy directory

Search by NCPDP 4106882, or by name and ZIP: Bayview Pharmacy, Warwick, RI 02886. Select it as the destination pharmacy and save it as a favorite. Click any value to copy it.

NCPDP4106882NPI1750455143Address3844 Post Rd, Warwick, RI 02886Phone(401) 284-4505Fax(401) 284-4506
2

Enter the formula as a compound

Compounded preparations have no NDC, so this formula will not appear in your EHR's drug search. Use your system's compound, non-formulary, or free-text prescription entry and name the preparation exactly as written in step 3. If your EHR forces you to pick a listed drug, pick the closest entry for the active ingredient and put the full formula in the prescription body (the Sig or directions field), not in Notes to Pharmacy.

Compounded preparations have no NDC and will not appear in your drug search. For EPCS to validate, select a drug entry your EHR recognizes as controlled, usually the bulk powder entry for the active ingredient (for example Ketamine (bulk) powder, not a branded product), then put the full formula from step 3 in the prescription body. A free-text entry that does not validate as controlled will be rejected by your EPCS module.

3

Copy the prescription details

RxFormula name
Dose formDose form
Quantity________
SigAs directed by prescriber
Refills____
PharmacyBayview Pharmacy, Warwick RI, NCPDP 4106882
Copy prescription details

Quantity and directions are starting points for this dose form, not treatment recommendations. Dosing remains the prescriber's responsibility.

4

Send it

Transmit from your EHR. For this non-controlled preparation we also accept fax to (401) 284-4506 and phoned orders at (401) 284-4505. Order forms are on the formulation pages and in the prescriber portal.

Transmit with two-factor authentication through your EPCS-enabled EHR. No order form is offered for this preparation; e-prescribing guides for our controlled preparations are on the formulation pages.

Do not use Notes to Pharmacy for the formula. Some EHRs keep that field internal and never transmit it. A prescription that arrives without the formula is delayed while we call your office.

Licensed to dispense in RI, MA, CT, NJ, NH, FL, ME, and PA; New York is served on a limited basis while nonresident registration is pending. Compounded preparations are not FDA-approved. A valid prescription is required. Full guide, including steps by EHR: How to e-prescribe to Bayview. Questions about this formula: call (401) 284-4505.

Propranolol Hydrochloride 20 mg/mL Sublingual Solution
Sublingual Solution
30 mL
controlled

Place dropper amount under the tongue

As needed