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Formulas

Lorazepam 1 mg/Diphenhydramine HCl 12.5 mg/Haloperidol 2 mg/Metoclopramide 20 mg Suppository

The Lorazepam 1 mg/Diphenhydramine HCl 12.5 mg/Haloperidol 2 mg/Metoclopramide 20 mg Suppository is a compounded medication. This solid dosage form is inserted into a body cavity, typically the rectum or vagina, where it dissolves or melts. The medication is then released for local or systemic absorption. It is used to treat conditions such as insomnia, anxiety, schizophrenia, nausea, and vomiting.

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Formula Information

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The Bayview Pharmacy team of compounding pharmacists has meticulously developed a suppository formulation of Lorazepam 1 mg/Diphenhydramine HCl 12.5 mg/Haloperidol 2 mg/Metoclopramide 20 mg. This unique formulation is designed to address a range of disease states, including anxiety, insomnia, nausea, and vomiting.

The combination of Lorazepam and Diphenhydramine HCl in this formulation works synergistically to alleviate anxiety and promote restful sleep. Concurrently, Haloperidol and Metoclopramide are included for their efficacy in reducing nausea and vomiting. This comprehensive formulation provides an effective treatment strategy for these conditions and is suitable for use in both adult and pediatric patients.

For patients, this suppository formulation offers a user-friendly and efficient method of medication administration. It is designed to dissolve or melt once inserted into a body cavity, typically the rectum or vagina, releasing the medication for local or systemic absorption. This allows for rapid relief from symptoms. It is crucial, however, to adhere strictly to the usage instructions provided by your healthcare provider to ensure optimal results and safety.

For healthcare providers, this formulation presents a potent and versatile treatment option for managing anxiety, insomnia, nausea, and vomiting in patients. It is essential to consider the potential side effects of the individual components when prescribing this formulation. We encourage healthcare providers to contact us with any queries or concerns about this formulation. Our team is committed to providing comprehensive information and support to ensure the best possible patient outcomes.

Drug Interactions

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The Lorazepam 1 mg/Diphenhydramine HCl 12.5 mg/Haloperidol 2 mg/Metoclopramide 20 mg Suppository is a compounded formulation designed for the treatment of various conditions such as nausea, vomiting, anxiety, and agitation. Each component of this formulation plays a specific role in managing these conditions. Lorazepam, a benzodiazepine, is utilized for its calming effects on the brain and nerves, thus helping to reduce anxiety and agitation. Diphenhydramine HCl, an antihistamine, is effective in controlling nausea and vomiting. Haloperidol, an antipsychotic medication, is used to manage agitation. Lastly, Metoclopramide, a prokinetic agent, aids in the treatment of nausea and vomiting.

Patients should be aware that this formulation may cause side effects such as drowsiness, dizziness, and confusion. It is advised not to drive or operate machinery until the effects of the medication are fully understood. Additionally, this formulation may cause an increase in blood pressure, heart rate, and respiration. Regular monitoring for these side effects is recommended.

It is important to note that this formulation may interact with other medications, including but not limited to antacids, anticonvulsants, antihistamines, and other benzodiazepines. Therefore, patients should inform their healthcare provider of all medications they are currently taking before starting this treatment.

Healthcare providers prescribing this formulation should also be aware of the potential for increased blood pressure, heart rate, and respiration in patients. Regular monitoring for these side effects is advised. Additionally, potential interactions with other medications, including antacids, anticonvulsants, antihistamines, and other benzodiazepines, should be considered.

If you have any questions or concerns about this formulation or its potential interactions, please do not hesitate to contact your healthcare provider for further information and guidance.

How Does it Work

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This compounded formulation combines Lorazepam 1 mg, Diphenhydramine HCl 12.5 mg, Haloperidol 2 mg, and Metoclopramide 20 mg in a suppository form. Each of these active ingredients serves a specific purpose in treating a variety of conditions such as anxiety, insomnia, nausea, and vomiting.

Lorazepam, a benzodiazepine, is known for its ability to alleviate anxiety and induce sleep. Diphenhydramine HCl, an antihistamine, is effective in reducing symptoms of nausea and vomiting. Haloperidol, an antipsychotic medication, is used to manage anxiety and agitation. Lastly, Metoclopramide, a prokinetic agent, is utilized to mitigate nausea and vomiting.

The suppository is designed to be inserted into the rectum, where it dissolves to release the medication. The active ingredients are then absorbed into the bloodstream, with the effects typically felt within 30 minutes to 1 hour.

It is crucial to use this formulation as directed by a healthcare provider. It is not recommended for children under the age of 18. Prior to using this formulation, it is advisable to discuss potential side effects with your healthcare provider. This ensures that you are fully informed about the medication and can make an informed decision about your treatment.

If you have any questions or concerns about this formulation or its mechanism of action, please do not hesitate to contact us at Bayview Pharmacy. We are committed to helping you find the most suitable treatment option for your condition.

Other Uses

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This compounded formulation of Lorazepam 1 mg/Diphenhydramine HCl 12.5 mg/Haloperidol 2 mg/Metoclopramide 20 mg Suppository is a versatile medication that can be used to treat a wide range of conditions. It is particularly effective in managing insomnia, anxiety, schizophrenia, nausea, and vomiting. Additionally, it can be used to alleviate symptoms associated with muscle spasms, irritable bowel syndrome, and motion sickness.

One of the key advantages of this formulation is its suppository form, which is especially beneficial for patients who have difficulty swallowing pills or capsules. The suppository is inserted into a body cavity, typically the rectum or vagina, where it dissolves or melts to release the medication. This allows for quick absorption and can provide relief within minutes.

This formulation can also be used to manage symptoms of opioid withdrawal, such as nausea, vomiting, and muscle spasms. However, it is crucial to note that this medication should only be used under the supervision of a healthcare professional. Patients should discuss any potential risks and benefits with their doctor before using this formulation.

It's important to be aware that this formulation may cause drowsiness. As such, it should not be used while operating a motor vehicle or machinery. Always ensure to use this medication responsibly and in accordance with the advice of your healthcare provider.

If you have any questions about this formulation or any other compounding medications, please don't hesitate to reach out. We are here to help you find the best treatment option for your individual needs.

Frequently Asked Questions

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What is the Lorazepam/Diphenhydramine/Haloperidol/Metoclopramide Suppository?

This is a compounded medication that combines Lorazepam, Diphenhydramine, Haloperidol, and Metoclopramide in a solid dosage form. It is designed to be inserted into a body cavity, typically the rectum or vagina, where it dissolves or melts to release the medication for local or systemic absorption.

What is the purpose of this medication?

This medication is typically used to manage symptoms such as nausea, vomiting, agitation, and anxiety, particularly in palliative care settings. The combination of these four drugs can provide comprehensive symptom management.

How should I use this suppository?

The suppository should be inserted into the rectum or vagina as directed by your healthcare provider. It will dissolve or melt to release the medication.

What are the potential side effects of this medication?

Side effects can include drowsiness, dizziness, dry mouth, constipation, blurred vision, or unsteadiness. If any of these effects persist or worsen, notify your doctor or pharmacist promptly.

Can I take this medication if I am pregnant or breastfeeding?

Consult your healthcare provider before using this medication if you are pregnant, planning to become pregnant, or are breastfeeding. The effects on the fetus or infant are not fully known.

What should I do if I miss a dose?

If you miss a dose, use it as soon as you remember. If it is near the time of the next dose, skip the missed dose. Use your next dose at the regular time. Do not double the dose to catch up.

Can I drink alcohol while using this medication?

Alcohol can increase the nervous system side effects of these medications such as dizziness, drowsiness, and difficulty concentrating. It is best to avoid or limit the use of alcohol while being treated with these medications.

What should I do if I experience an allergic reaction?

If you experience signs of an allergic reaction such as rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, or trouble breathing, seek medical attention immediately.

Can I drive or operate machinery after using this medication?

This medication may cause drowsiness or dizziness. Do not drive, use machinery, or do anything that needs alertness until you can do it safely.

How should I store this medication?

Store at room temperature away from light and moisture. Do not store in the bathroom. Keep all medications away from children and pets.

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Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.

No compounded medications are reviewed by the FDA for safety or efficacy.