Lidocaine HCl 23%/Tetracaine HCl 7% Topical Gel is a compounded medication designed to provide local anesthesia by topical application. This semisolid formulation is dispensed through a pump mechanism, which allows for easy and precise dosing. The gel base offers a convenient medium for the active ingredients to be applied directly to the skin, ensuring targeted treatment and effective absorption. The combination of Lidocaine, a well-known amide local anesthetic, and Tetracaine, an ester local anesthetic, works synergistically to provide a rapid onset and prolonged duration of action for numbing the skin.

The high concentration of Lidocaine HCl at 23% serves to block the sodium channels in the neuronal membrane, thereby preventing the initiation and conduction of nerve impulses. Tetracaine HCl at 7% complements this action by stabilizing the neuronal membrane, which enhances the overall anesthetic effect. This formulation is particularly useful in procedures that require superficial anesthesia of the skin, such as minor surgical procedures, laser treatments, tattoo application and removal, and the management of chronic painful conditions like neuropathic pain.

Patients and prescribers should be aware that the use of this topical gel should be limited to intact skin surfaces, and care should be taken to avoid application to mucous membranes or broken skin. The duration of effect and the onset time can vary depending on the site of application and individual patient factors. It is also important to consider the maximum safe dose of the anesthetic agents to avoid systemic toxicity, particularly in patients with underlying health conditions or those taking concomitant medications that may interact with local anesthetics.

For optimal results, the gel should be applied as directed by the prescriber, and the area of application should be clean and dry. Patients should be advised to report any adverse reactions such as persistent redness, swelling, or allergic symptoms. As with all compounded medications, this formulation is prepared specifically for individual patients in our state-of-the-art compounding facility at Bayview Pharmacy, ensuring the highest quality and safety standards.

If you have any questions regarding the Lidocaine HCl 23%/Tetracaine HCl 7% Topical Gel or its appropriate use for different disease states, please do not hesitate to reach out to us. Our team of knowledgeable compounding pharmacists is committed to providing comprehensive support and guidance to both patients and prescribers to ensure the safe and effective use of this specialized medication.

Lidocaine HCl and Tetracaine HCl are both local anesthetics used topically to numb the skin and surrounding tissues. When combined in a 23%/7% topical gel, they provide a potent anesthetic effect for various minor surgical procedures, such as laser hair removal, tattoo application and removal, and superficial skin surgeries. The gel's semisolid consistency, dispensed through a pump mechanism, allows for precise dosing and targeted application.

While the risk of systemic drug interactions is generally low with topical application due to minimal systemic absorption, certain interactions may still occur, particularly in cases of excessive use, application to large surface areas, or use on compromised skin. Patients should be advised to inform their healthcare providers of all medications they are currently taking, including prescription drugs, over-the-counter medications, and herbal supplements.

Concomitant use of other local anesthetics or medications with a similar metabolic pathway (primarily amide-type local anesthetics) may increase the risk of systemic toxicity. Caution is advised when using this formulation alongside other drugs that can cause methemoglobinemia, such as sulfonamides, acetaminophen, and nitrates, as both lidocaine and tetracaine can contribute to this condition.

Patients taking class I antiarrhythmic drugs (such as tocainide and mexiletine) or other medications that affect cardiac conduction should use this formulation with caution, as lidocaine has the potential to exacerbate effects on cardiac function. Additionally, the use of this gel in conjunction with other CNS depressants, including opioids, sedatives, or alcohol, may increase the risk of CNS side effects, although this is more of a concern with systemic administration of lidocaine.

Enzyme inducers or inhibitors of cytochrome P450 3A4 (CYP3A4) may affect the metabolism of lidocaine. Medications such as certain anticonvulsants, macrolide antibiotics, and cimetidine could potentially alter lidocaine levels, leading to increased risk of toxicity or decreased efficacy.

Patients with hepatic impairment may have an increased risk of systemic toxicity due to decreased metabolism of lidocaine and tetracaine. Similarly, patients with severe renal impairment may have an increased risk of systemic toxicity due to decreased excretion of the metabolites of these drugs.

It is important to use this formulation as directed and to avoid applying it to broken or inflamed skin, as this can increase systemic absorption. The gel should not be used in patients with a known hypersensitivity to lidocaine, tetracaine, or other amide or ester local anesthetics. Additionally, care should be taken to avoid contact with the eyes, as this can lead to severe irritation and possible harm.

For any questions or concerns regarding the use of this formulation or potential drug interactions, please reach out to us at Bayview Pharmacy. Our team of compounding pharmacists is available to provide guidance and support to ensure the safe and effective use of this medication.

The Lidocaine HCl 23%/Tetracaine HCl 7% Topical Gel is a compounded medication designed to provide local anesthesia by topical application. This semisolid formulation is dispensed through a pump mechanism, which allows for easy and precise application on the skin. The gel-like consistency ensures that the medication stays where it is applied, providing targeted treatment and facilitating the absorption of the active ingredients.

Lidocaine and Tetracaine are both local anesthetics that work by blocking sodium channels in the neuronal cell membrane. When applied to the skin, these drugs prevent the initiation and conduction of nerve impulses, thereby producing a numbing effect. Lidocaine acts relatively quickly and has a medium duration of action, while Tetracaine has a slower onset but provides a longer duration of anesthesia. The combination of these two anesthetics in a single formulation offers both rapid onset and extended duration of action, making it particularly useful for procedures that require a prolonged numbing effect.

This compounded gel is commonly used for a variety of dermatological and cosmetic procedures, such as laser hair removal, tattoo application and removal, and minor surgical procedures that do not require deep anesthesia. It is also used to numb the skin before needle insertions, such as those for IV starts or blood draws. The high concentration of active ingredients in this formulation is specifically designed for procedures that require a significant numbing effect on the surface of the skin.

Patients and prescribers should be aware that the use of this topical anesthetic should be limited to intact skin. It is not intended for use on mucous membranes or in the eyes. The area of application should be clean and dry before the gel is applied. The amount of gel used and the duration of application should be as directed by a healthcare professional, as excessive use or prolonged application can lead to increased absorption and potential systemic effects.

As with any medication, there are potential side effects, including but not limited to redness, swelling, and allergic reactions at the site of application. Systemic side effects are rare but can occur if the medication is absorbed in large amounts, which is why it is important to follow the prescribed dosing instructions. If you experience any adverse effects or have concerns about the use of this medication, please contact your healthcare provider immediately.

If you have any questions about the Lidocaine HCl 23%/Tetracaine HCl 7% Topical Gel or its application, please do not hesitate to reach out to us at Bayview Pharmacy. Our team of compounding pharmacists is here to provide you with the information and support you need to effectively use this formulation.

The combination of Lidocaine HCl 23% and Tetracaine HCl 7% in a topical gel formulation is primarily employed for its powerful anesthetic properties, designed to provide localized relief of pain and discomfort. Beyond its conventional use for numbing the skin in preparation for minor surgical procedures, such as dermal filler injections, laser hair removal, or tattoo application and removal, this gel may offer a broader utility in various medical situations.

Physicians might recommend this topical anesthetic for the management of chronic pain conditions that are localized and would benefit from surface numbness, such as neuropathic pain or post-herpetic neuralgia. Moreover, the soothing effect of the gel can be an adjunct treatment option for conditions like burns, superficial wounds, or insect bites, where pain relief at the skin level is desired. In certain cases, it might also help to relieve the itching and discomfort associated with skin conditions such as eczema or psoriasis when traditional treatments are insufficient or not well-tolerated.

In the sphere of sports medicine, this topical gel may assist in the temporary relief of muscle or joint pain stemming from minor injuries or strains. Similarly, it can function as a supportive treatment for patients with specific localized musculoskeletal conditions, providing temporary respite from pain while other longer-acting therapeutic interventions take effect. It is essential, however, to use this medication under the guidance of a healthcare professional, as inappropriate use can lead to adverse effects or reduce its efficacy.

Dentists might also utilize this gel for various intraoral applications, aiming to alleviate discomfort associated with procedures like scaling, root planing, or the management of mucosal lesions. It can be used to numb the gum area before injections for more invasive dental work, helping to minimize the initial discomfort of the needle.

While the use of Lidocaine HCl 23%/Tetracaine HCl 7% Topical Gel extends to a variety of applications, each for the purpose of localized pain relief, it is critical that both patients and prescribers are aware of the potential risks, such as allergic reactions or systemic absorption leading to toxicity if applied over a large surface area or for a protracted period. The product's efficacy and safety profile should be weighed carefully against the condition being treated, and it should only be used as directed by a healthcare provider. If you have any questions regarding the expanded use of this formulation or any other inquiries, please do not hesitate to reach out to us at Bayview Pharmacy for further assistance and guidance.