The Lidocaine 10%/Tetracaine 1.3%/Tetracaine HCl 1.3% Topical Gel is a compounded medication designed to provide local anesthesia by topical application. This semisolid formulation is specifically compounded for patients who require a potent anesthetic effect on the skin for various procedures or conditions. The gel is dispensed through a pump mechanism, which allows for easy and precise dosing, ensuring that the correct amount of medication is applied to the desired area. The gel base offers a convenient and patient-friendly means of drug delivery, with a consistency that is easy to spread over the treatment area without dripping or running.

Lidocaine is a well-known local anesthetic and antiarrhythmic drug. It works by blocking sodium channels and, consequently, the transmission of nerve impulses, which numbs the treated area. Tetracaine and Tetracaine HCl are also local anesthetics that function by inhibiting the influx of sodium ions across neuronal membranes, leading to a loss of sensation. The combination of these two anesthetics in both base and hydrochloride salt forms provides a rapid onset and prolonged duration of anesthesia, making it particularly useful for procedures that require extended periods of numbness.

This compounded gel is commonly used for a variety of dermatological and procedural applications, including but not limited to, pre-procedural numbing for laser treatments, tattoo application and removal, minor surgical procedures, and the management of chronic pain conditions such as neuropathies. The high concentration of lidocaine combined with tetracaine enhances the depth and duration of anesthesia, providing significant relief from pain and discomfort during and after procedures.

It is important for both patients and prescribers to be aware that this formulation should be used with caution, as the high concentration of anesthetics can increase the risk of systemic absorption and potential toxicity if applied over large areas or used improperly. The use of this gel should be in accordance with the directions provided by the compounding pharmacist and the prescribing physician. Patients should be monitored for signs of local and systemic adverse effects, particularly in sensitive patient populations or when applied to broken or inflamed skin.

For any questions or concerns regarding the use of Lidocaine 10%/Tetracaine 1.3%/Tetracaine HCl 1.3% Topical Gel, or to discuss the suitability of this formulation for a specific patient or procedure, please do not hesitate to reach out to us at Bayview Pharmacy. Our team of compounding pharmacists is dedicated to providing comprehensive support and guidance to ensure the safe and effective use of compounded medications.

Lidocaine and tetracaine are both local anesthetics used to numb the skin and surrounding tissues. When used in combination, as in this topical gel formulation, they work synergistically to provide local anesthesia for various procedures or to alleviate pain from certain conditions. However, it is important to consider potential drug interactions when using this formulation.

Firstly, the use of this gel in conjunction with other local anesthetics should be approached with caution. The systemic absorption of lidocaine and tetracaine can be increased when applied to large areas or when occlusive dressings are used, potentially leading to additive systemic effects. Patients should be advised to limit the use of other local anesthetics while using this product to avoid excessive systemic exposure.

Patients taking Class I antiarrhythmic drugs (such as tocainide and mexiletine) or other medications that affect cardiac conduction should use this gel with caution, as lidocaine has the potential to exacerbate the effects of these drugs on the heart. Similarly, caution is advised when used in patients on beta-blockers or cimetidine, as these medications can potentially increase lidocaine plasma concentrations by inhibiting hepatic metabolism, leading to increased risk of systemic toxicity.

Enzyme inducers such as phenytoin, phenobarbital, and rifampin may increase the hepatic clearance of lidocaine, potentially reducing its efficacy. Conversely, enzyme inhibitors like fluvoxamine and sertraline may decrease the clearance of lidocaine, increasing the risk of toxicity. It is important to monitor patients for signs of toxicity and adjust the dose of lidocaine accordingly when used with these medications.

Caution is also advised when this gel is used in patients taking anti-arrhythmic drugs like amiodarone, which can potentiate the effects of lidocaine. Additionally, the use of this gel in patients on methemoglobin-inducing agents, such as nitrates, nitrites, and antimalarial drugs, may increase the risk of methemoglobinemia, a condition where the oxygen-carrying capacity of the blood is reduced.

It is essential to avoid applying this gel to broken or inflamed skin, as this can increase systemic absorption and the risk of adverse effects. Patients should be instructed to apply the gel as directed, avoiding application to large surface areas or using it for prolonged periods unless advised by a healthcare professional.

This topical gel is indicated for use in procedures requiring local anesthesia of the skin, such as laser hair removal, tattoo application and removal, and minor surgical procedures. It may also be used to alleviate pain from conditions such as postherpetic neuralgia or other neuropathic pain syndromes. The efficacy of this gel in providing local anesthesia helps to reduce pain and discomfort during these procedures or conditions.

Patients and prescribers should be aware of the potential for systemic side effects, particularly with excessive use or in patients with pre-existing cardiac conditions. It is important to use this medication as directed and report any unusual symptoms or side effects to a healthcare provider immediately. If you have any questions or concerns regarding the use of this formulation or potential drug interactions, please reach out to us at Bayview Pharmacy for further assistance.

The Lidocaine 10%/Tetracaine 1.3%/Tetracaine HCl 1.3% Topical Gel is a compounded medication designed to provide localized anesthesia by numbing the skin and surrounding tissues. This formulation combines two potent local anesthetics, lidocaine and tetracaine, in both its base and hydrochloride (HCl) salt forms, to create a synergistic effect that enhances the depth and duration of anesthesia.

Lidocaine works by blocking sodium channels in the neuronal cell membrane. This action inhibits the initiation and conduction of nerve impulses, thereby providing a numbing sensation and temporary loss of sensation in the area where the gel is applied. Tetracaine, similarly, acts to stabilize the neuronal membrane and decrease its permeability to sodium ions, which further prolongs the local anesthetic effect. The combination of these two anesthetics in different forms allows for a rapid onset of action due to the lidocaine, with an extended duration of effect provided by the tetracaine.

The semisolid gel formulation is specifically designed for topical application. It is dispensed through a pump mechanism, which allows for easy and precise dosing. The gel base facilitates adherence to the skin and ensures that the active ingredients remain in contact with the treatment area, providing consistent and effective anesthesia. This is particularly beneficial for procedures that require a localized area to be numbed without affecting the surrounding regions.

This compounded gel is commonly used for a variety of dermatological and cosmetic procedures, such as laser hair removal, tattoo application and removal, and minor surgical procedures. It is also used to alleviate pain from needle insertions, such as those required for intravenous starts or injections. The gel's anesthetic properties can significantly reduce the discomfort associated with these procedures.

For patients and prescribers considering the use of this formulation, it is important to understand that while the gel provides effective local anesthesia, it should be used with caution in patients with a history of sensitivity to local anesthetics or those with certain medical conditions. The gel should be applied as directed by a healthcare professional, and the area of application should be limited to avoid systemic absorption, which could lead to toxicity. Additionally, the duration of application should be carefully monitored to prevent overuse.

If you have any questions or require further information about the Lidocaine 10%/Tetracaine 1.3%/Tetracaine HCl 1.3% Topical Gel, please reach out to us at Bayview Pharmacy. Our team of compounding pharmacists is here to provide guidance and support to ensure the safe and effective use of this medication.

The combination of lidocaine and tetracaine found in this topical gel formulation can be employed for a variety of uses beyond the primarily indicated local anesthesia. While it is commonly used to numb the skin prior to procedures such as injections, venipuncture, or minor dermatological treatments, the analgesic properties of this gel can also be beneficial for the relief of pain associated with other conditions.

For instance, this topical preparation may serve as an adjunct treatment for superficial neuropathic pain, where nerve dysfunction leads to pain sensations on the skin. It has been occasionally used off-label for the relief of discomfort from conditions such as post-herpetic neuralgia (the lingering pain following a shingles outbreak) or for the itchiness and pain from certain skin irritations or insect bites. Furthermore, patients with chronic conditions, such as painful diabetic neuropathy, might find temporary relief from the numbing effects of this gel.

Some patients might also use this gel to minimize discomfort associated with the healing of skin abrasions or minor burns. Moreover, those undergoing tattoo application or laser hair removal have reported benefit from the numbing effect of similar formulations, although this specific use should be approached with caution and only under the advice of a healthcare provider due to potential interactions with the processes involved in these procedures.

In sports medicine, there is anecdotal evidence of this kind of formulation being utilized for the temporary relief of muscular or joint pain, although its efficacy in these applications has not been well studied. Similarly, those with conditions causing chronic pain might explore the use of this gel under the guidance and strict supervision of their healthcare provider to manage acute flare-ups of pain on specific, localized areas of the skin.

It is important to note that all these additional uses of the lidocaine and tetracaine topical gel should be considered on a case-by-case basis and always under the supervision of a healthcare professional. The safety and effectiveness of the gel for these secondary uses vary among individuals and have not been established by rigorous clinical trials. Therefore, patients interested in utilizing this medication for conditions other than the standard indications should have a thorough discussion with their prescriber about the potential risks and benefits.

If you have any questions or require more information about the potential uses of this formulation, please do not hesitate to reach out to us at Bayview Pharmacy. Our team of compounding pharmacists is ready to provide detailed information and support for both patients and prescribers regarding the use of this preparation in various therapeutic contexts.