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Formulas

Ivermectin 1% Oral Liquid

The Ivermectin 1% Oral Liquid is a specially compounded medication designed for oral use, offering a precise 1% concentration of the active ingredient, Ivermectin. This formulation is created to provide a convenient alternative for patients who have difficulty swallowing pills or tablets, making it particularly suitable for use in pediatric and geriatric patients. The liquid form ensures ease of administration and allows for accurate dosing.

Ivermectin is an antiparasitic agent that is effective in treating a variety of parasitic infections. This includes onchocerciasis (river blindness), strongyloidiasis of the intestinal tract, and other conditions caused by parasitic worms. Additionally, Ivermectin is used in the treatment of certain forms of scabies and lice, which are ectoparasitic infestations. The 1% oral liquid formulation facilitates adherence to treatment regimens in patients who require a liquid dosage form.

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Formula Information

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Ivermectin 1% Oral Liquid is a specially compounded medication designed for oral use, providing a precise 1% concentration of ivermectin in a liquid form. This formulation is particularly beneficial for patients who have difficulty swallowing pills or tablets, such as children and the elderly, or for those who require a more easily adjustable dosing. The liquid form allows for accurate dosing, which is critical for the effectiveness and safety of the medication.

Ivermectin is an antiparasitic agent that works by binding to invertebrate muscle and nerve cells of parasites, causing paralysis and death of the parasite. It is commonly used to treat a variety of parasitic infections, including onchocerciasis (river blindness), strongyloidiasis, and other diseases caused by soil-transmitted helminthiasis, as well as scabies. It has also been used off-label for the treatment of certain viral infections, although its efficacy in these cases is still under investigation and should be considered with caution.

For patients and prescribers considering Ivermectin 1% Oral Liquid, it is important to note that the dosage and duration of treatment will vary depending on the specific parasitic infection being treated. It is essential to follow the dosing instructions provided by the healthcare provider or the compounding pharmacist to ensure optimal outcomes. Additionally, patients should be monitored for side effects, which can include gastrointestinal symptoms, dizziness, and skin rash, among others. As with any medication, it is crucial to discuss the potential risks and benefits with a healthcare professional before starting treatment.

At Bayview Pharmacy, we are committed to providing high-quality compounded medications tailored to the needs of our patients. Our team of knowledgeable compounding pharmacists is available to answer any questions and provide guidance on the use of Ivermectin 1% Oral Liquid. If you have any questions or require further information about this formulation, please do not hesitate to reach out to us.

Drug Interactions

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Ivermectin is an antiparasitic agent used to treat various parasitic infections, such as onchocerciasis, strongyloidiasis, and scabies. When considering the use of ivermectin 1% oral liquid, it is important to be aware of potential drug interactions that may affect the efficacy of the treatment or increase the risk of adverse effects. Ivermectin is metabolized primarily by the CYP3A4 enzyme in the liver, and drugs that affect this enzyme can alter the levels of ivermectin in the body.

Concomitant use of ivermectin with strong CYP3A4 inhibitors, such as ketoconazole, itraconazole, clarithromycin, and grapefruit juice, can increase plasma concentrations of ivermectin, potentially leading to increased risk of ivermectin toxicity. Symptoms of toxicity may include headache, dizziness, muscle pain, nausea, or diarrhea. On the other hand, co-administration with strong CYP3A4 inducers, such as rifampin, phenytoin, carbamazepine, and St. John's Wort, may decrease ivermectin levels, reducing its efficacy against parasitic infections.

Additionally, ivermectin may enhance the anticoagulant effect of warfarin and other coumarin anticoagulants, leading to an increased risk of bleeding. Patients on anticoagulant therapy should be closely monitored for changes in prothrombin time or international normalized ratio (INR) when starting or stopping ivermectin treatment. It is also advisable to avoid the use of ivermectin with other drugs known to have a high potential for central nervous system (CNS) effects, as ivermectin may potentiate the CNS depressant effects of these medications.

Patients with concurrent infections or those taking other antiparasitic drugs should consult with a healthcare provider before using ivermectin, as drug-drug interactions may occur. It is also important to consider the potential for interactions with over-the-counter medications, herbal supplements, and dietary factors that may influence the metabolism and efficacy of ivermectin.

Before prescribing or using ivermectin 1% oral liquid, a thorough medication review should be conducted to assess for potential drug interactions. Adjustments to therapy or additional monitoring may be necessary to ensure safe and effective use of this medication. If you have any questions or concerns regarding the use of ivermectin 1% oral liquid and potential drug interactions, please reach out to us at Bayview Pharmacy for further assistance.

How Does it Work

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Ivermectin 1% Oral Liquid is a specially compounded medication designed for ease of administration and precise dosing. This formulation is created by dissolving ivermectin, an antiparasitic agent, in a suitable solvent to achieve a 1% concentration, which means that each milliliter of the liquid contains 10 mg of ivermectin. The liquid form is particularly beneficial for patients who have difficulty swallowing pills, such as children and the elderly, or for those who require tailored dosing that may not be available in pre-manufactured tablet or capsule forms.

The mechanism of action of ivermectin involves binding selectively and with high affinity to glutamate-gated chloride channels, which are present in invertebrate nerve and muscle cells. This binding increases the permeability of the cell membrane to chloride ions, resulting in hyperpolarization of the nerve or muscle cell, leading to paralysis and death of the parasite. Ivermectin has a broad spectrum of activity against various parasitic organisms, including those causing diseases such as onchocerciasis (river blindness), strongyloidiasis, and scabies.

In the treatment of onchocerciasis, ivermectin targets the larval form of the parasite Onchocerca volvulus. It is less effective against adult worms but can significantly reduce the number of skin microfilariae, thereby alleviating symptoms and halting the progression of the disease. For strongyloidiasis, caused by the nematode Strongyloides stercoralis, ivermectin is effective in eliminating the intestinal worms and preventing the potentially fatal hyperinfection syndrome. In the case of scabies, ivermectin is used when topical treatments have failed or are contraindicated. It acts by killing the mites responsible for the infestation, Sarcoptes scabiei.

It is important for patients and prescribers to understand that the dosing of ivermectin 1% Oral Liquid must be carefully calculated based on the patient's weight and the specific parasitic infection being treated. The pharmacists at Bayview Pharmacy are skilled in compounding this medication to ensure that each patient receives the correct dose. Additionally, our team can provide guidance on the duration of treatment and any necessary follow-up doses, as the treatment regimen can vary depending on the disease state and the patient's response to therapy.

For those interested in using Ivermectin 1% Oral Liquid, it is crucial to consult with a healthcare provider to determine if this medication is appropriate for your specific condition. If you have any questions or require further information about this formulation, please do not hesitate to reach out to us at Bayview Pharmacy. Our knowledgeable team of compounding pharmacists is here to assist you with your medication needs and to ensure safe and effective treatment.

Other Uses

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Ivermectin 1% Oral Liquid formulation is most commonly known for its use in treating certain parasitic roundworm infections, which can improve patients' quality of life and alleviate disease-related symptoms. However, the scope of its utilization extends beyond these indications. Off-label, it may also be employed as a potential treatment for other parasitic diseases depending on clinical judgment, regional prevalence of diseases, and sensitivity of the parasites, though these uses should always be guided by research and a healthcare professional’s discretion.

Furthermore, there is ongoing research into the broader antiviral properties of Ivermectin, which includes studies on its effects against some viruses. These studies are still in the experimental phase, and results have not yet solidified its role in treating viral infections in humans. Therefore, this use remains speculative and is not endorsed by current medical guidelines. It is paramount for prescribers to reference the latest scientific evidence and professional guidelines when considering off-label uses.

In some cases, Ivermectin has been used in veterinary medicine due to its efficacy in treating a broad spectrum of parasites in animals. This formulation specifically designed for human use must not be confused with veterinary products, which are formulated differently and may contain inactive ingredients that are not safe for human consumption. It is crucial that Ivermectin 1% Oral Liquid prescribed for humans is only used under the supervision of a healthcare provider, with dosing and treatment duration precisely tailored to the individual's needs to minimize risks and enhance therapeutic outcomes.

Patients or prescribers considering Ivermectin 1% Oral Liquid for uses other than its commonly prescribed indications should engage in a thorough consultation process. This includes discussing medical history, current medications, the potential benefits against risks, and the current evidence supporting alternative uses. If you're considering this medication for an unconventional purpose or have any questions regarding its use, please do not hesitate to reach out to us at Bayview Pharmacy. Our team of compounding pharmacists is dedicated to providing accurate, up-to-date information to help ensure the safe and effective use of the medications we provide.

Frequently Asked Questions

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What is Ivermectin 1% Oral Liquid used for?

Ivermectin 1% Oral Liquid is used to treat certain parasitic infections in the body, including those caused by roundworms, lice, and certain skin conditions. It works by paralyzing and killing parasites.

How should Ivermectin 1% Oral Liquid be taken?

It should be taken on an empty stomach with a full glass of water, as directed by your healthcare provider. The dosage is usually based on your weight, medical condition, and response to treatment.

Can children and the elderly take Ivermectin 1% Oral Liquid?

Yes, this form of ivermectin is suitable for both pediatric and geriatric patients, particularly those who have trouble swallowing solid forms of medication. However, the dosage may differ, and it should be used under medical supervision.

What are the benefits of using a liquid formulation of Ivermectin?

The liquid form allows for accurate dosing, is easier to swallow than pills or tablets, and can be a convenient option for those with swallowing difficulties or those who require precise dosing, such as children and elderly patients.

Can Ivermectin 1% Oral Liquid be mixed with food or drink to improve its taste?

It is generally recommended to take the medication on an empty stomach for better absorption. However, if you have difficulty with the taste, check with your healthcare provider if it can be mixed with a small amount of water, juice, or applesauce.

How do I store Ivermectin 1% Oral Liquid?

Store at room temperature away from light and moisture. Do not store in the bathroom, and keep all medications away from children and pets. Refer to the product label for specific storage instructions.

Are there any side effects associated with Ivermectin 1% Oral Liquid?

Possible side effects may include dizziness, headache, muscle aches, nausea, or diarrhea. If any of these effects persist or worsen, contact your doctor or pharmacist promptly.

What should I do if I miss a dose of Ivermectin 1% Oral Liquid?

If you miss a dose, take it as soon as you remember. If it is near the time of the next dose, skip the missed dose. Take your next dose at the regular time. Do not double the dose to catch up.

Can Ivermectin 1% Oral Liquid interact with other medications?

Yes, like all medications, ivermectin can interact with other drugs. It's important to inform your healthcare provider of all medications you are taking, including prescription, over-the-counter, and herbal products.

Is it safe to take Ivermectin 1% Oral Liquid during pregnancy or while breastfeeding?

The safety of ivermectin during pregnancy and breastfeeding has not been well-established. If you are pregnant or breastfeeding, consult your healthcare provider before taking this medication.

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Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.

No compounded medications are reviewed by the FDA for safety or efficacy.