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Formulas

Enalapril Maleate 10 mg/ml Oral Liquid

Our Enalapril Maleate 10 mg/ml Oral Liquid is a specially compounded medication designed for oral use, offering a precise and manageable alternative for patients who require Enalapril in a liquid form. This formulation is particularly beneficial for individuals who have difficulty swallowing pills, such as children and the elderly. Enalapril Maleate is an angiotensin-converting enzyme (ACE) inhibitor that is commonly prescribed to treat a variety of cardiovascular conditions, including high blood pressure (hypertension), congestive heart failure, and left ventricular dysfunction after a myocardial infarction. The liquid dosage form ensures accurate dosing and ease of administration, enhancing patient compliance and therapeutic outcomes in the management of these disease states.

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Enalapril Maleate
Oral Liquid
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Formula Information

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Enalapril Maleate 10 mg/ml Oral Liquid is a specially compounded medication designed for ease of administration and precise dosing. This oral liquid formulation is particularly beneficial for patients who have difficulty swallowing tablets or capsules, such as children and the elderly. The medication is intended to be taken by mouth, and the liquid form allows for flexible dosing that can be adjusted according to the specific needs of the patient.

Enalapril Maleate is an angiotensin-converting enzyme (ACE) inhibitor, which is commonly used in the treatment of hypertension (high blood pressure) and heart failure. By inhibiting the action of ACE, enalapril decreases the production of angiotensin II, a substance that narrows blood vessels and releases hormones that can raise blood pressure. As a result, blood vessels relax and widen, making it easier for the heart to pump blood, and thus, lowering blood pressure and reducing the heart's workload. This can improve symptoms of heart failure and increase survival after a heart attack.

For patients with hypertension, Enalapril Maleate can help prevent the complications of high blood pressure such as stroke and myocardial infarction. In those with heart failure, it can improve the quality of life by reducing symptoms such as shortness of breath and swelling in the legs. It is important for prescribers to monitor kidney function and potassium levels in patients taking enalapril, as it can affect renal function and cause hyperkalemia. Additionally, patients should be advised to report any signs of angioedema, cough, or other side effects.

It is crucial for patients and prescribers to work closely with their compounding pharmacist to ensure the correct dosage and administration of Enalapril Maleate Oral Liquid. The pharmacists at Bayview Pharmacy are available to answer any questions and provide guidance on the use of this medication. We are committed to ensuring that each patient receives personalized care and the most appropriate treatment for their condition. If you have any questions or need further information about this formulation, please do not hesitate to reach out to us.

Drug Interactions

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Enalapril Maleate is an angiotensin-converting enzyme (ACE) inhibitor used in the treatment of hypertension and some types of chronic heart failure. When considering the use of Enalapril Maleate 10 mg/ml Oral Liquid, it is important to be aware of potential drug interactions that may affect the efficacy of the medication or increase the risk of adverse effects.

Enalapril can interact with other blood pressure-lowering agents, such as diuretics, beta-blockers, and calcium channel blockers, potentially leading to an additive hypotensive effect. Careful monitoring of blood pressure is advised when initiating or adjusting the dose in combination with these medications. Additionally, the use of potassium-sparing diuretics or potassium supplements alongside Enalapril may increase the risk of hyperkalemia, a condition characterized by high levels of potassium in the blood. Regular monitoring of serum potassium levels is recommended.

Nonsteroidal anti-inflammatory drugs (NSAIDs), including over-the-counter options like ibuprofen and naproxen, can reduce the antihypertensive effect of Enalapril and increase the risk of renal impairment, especially in patients with pre-existing kidney dysfunction. Patients should be advised to use NSAIDs cautiously and to inform their healthcare provider if they experience any signs of kidney problems, such as reduced urine output or swelling in the extremities.

Enalapril may also interact with lithium, a medication used for bipolar disorder, leading to increased lithium levels and potential toxicity. Frequent monitoring of lithium levels is necessary when used concurrently with Enalapril. Additionally, co-administration with medications that affect the renin-angiotensin system, such as angiotensin receptor blockers (ARBs) or aliskiren, may increase the risk of hypotension, hyperkalemia, and renal impairment. Such combinations should be used with caution and under close medical supervision.

Patients with diabetes should be aware that Enalapril may enhance the blood-glucose-lowering effect of insulin and oral antidiabetic agents, which may necessitate an adjustment in the dosage of these medications. Regular monitoring of blood glucose levels is advised when starting or changing the dose of Enalapril.

It is important for patients and prescribers to be aware of all medications, supplements, and over-the-counter drugs that are being taken to avoid potential interactions with Enalapril Maleate Oral Liquid. This includes not only prescription drugs but also herbal supplements and non-prescription medications. If you have any questions or concerns regarding the use of Enalapril Maleate 10 mg/ml Oral Liquid and potential drug interactions, please reach out to us at Bayview Pharmacy for further assistance and guidance.

How Does it Work

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Enalapril Maleate is an angiotensin-converting enzyme (ACE) inhibitor used in the treatment of hypertension (high blood pressure) and some types of chronic heart failure. The active ingredient, enalapril, works by blocking the action of a compound in the body called angiotensin-converting enzyme. Normally, this enzyme produces another compound called angiotensin II, as part of the body's natural control of blood pressure. Angiotensin II causes blood vessels to constrict and narrow, which increases the pressure within the vessels. By inhibiting the production of angiotensin II, enalapril causes blood vessels to relax and widen, which in turn lowers the blood pressure. Lowering high blood pressure helps prevent strokes, heart attacks, and kidney problems.

Enalapril is also beneficial in treating heart failure, as it reduces the strain on the heart by decreasing the pressure it needs to pump against. In addition, it improves the efficiency of the heart's pumping action and has been shown to improve symptoms and reduce hospitalizations related to heart failure.

The Enalapril Maleate 10 mg/ml Oral Liquid formulation is specifically designed to provide a convenient and easily ingested form of this medication. This is particularly useful for patients who have difficulty swallowing tablets or capsules, such as pediatric and geriatric patients, or those with certain medical conditions that affect swallowing. The liquid form allows for accurate dosing, which is critical for managing conditions like hypertension and heart failure, where precise dosing can significantly impact the patient's health and treatment outcomes.

When using this liquid formulation, it is important to shake the bottle well before each use to ensure that the medication is evenly distributed. Patients should use the provided measuring device to ensure they are taking the correct dose as prescribed by their healthcare provider. It is also important to store the medication as directed, typically at room temperature away from light and moisture, to maintain its effectiveness.

For patients and prescribers considering the use of Enalapril Maleate 10 mg/ml Oral Liquid, it is essential to understand that while this medication can greatly aid in controlling blood pressure and managing heart failure, it must be used under the guidance of a healthcare professional. Regular monitoring of blood pressure, kidney function, and electrolyte levels is necessary to ensure safe and effective use of the medication. Additionally, patients should be aware of potential side effects, which can include dizziness, lightheadedness, or dry cough.

If you have any questions about the Enalapril Maleate 10 mg/ml Oral Liquid formulation or its use in treating hypertension and heart failure, please reach out to us at Bayview Pharmacy. Our team of compounding pharmacists is here to provide you with the information and support you need to ensure the best possible outcomes for your health.

Other Uses

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Enalapril Maleate, an angiotensin-converting enzyme (ACE) inhibitor, is commonly prescribed for the management of hypertension and heart failure. However, the 10 mg/ml oral liquid formulation of Enalapril Maleate can also cater to patients who have difficulty managing diabetic nephropathy, a kidney complication of diabetes. This formulation allows for tailored dosing adjustments necessary for patients with renal impairment, serving as an off-label but highly advantageous use of this medication.

Beyond these primary indications, Enalapril Maleate oral liquid may also be considered in other scenarios where medication delivery is a concern. For example, patients with neurologic conditions or developmental disorders that impact swallowing may benefit from the liquid form. Additionally, patients who have undergone specific surgeries of the esophagus or gastrointestinal tract might find swallowing tablets or capsules uncomfortable or impractical; thus, this liquid formulation may be preferred during their recovery period. Also, patients with certain mental health disorders who exhibit pill aversion or mistrust may be more amenable to a liquid medication, which can benefit their adherence to a prescribed treatment regimen.

Despite these alternative uses, it is essential to emphasize that any off-label application of Enalapril Maleate oral liquid should be under the guidance of a healthcare professional, taking into account the patient's full medical history and concomitant medications. Monitoring for potential side effects, such as hypotension, hyperkalemia, and renal function changes, remains equally critical in off-label use as in standard applications.

The versatility of the Enalapril Maleate liquid formulation is also advantageous in situations requiring dosage flexibility. Dose titration is often necessary in pediatric and geriatric patients due to their varying body weights and metabolic rates. This form of the medication allows for precise dose adjustments to ensure optimal therapeutic outcomes customised to each patient's requirement. It also facilitates continuity of care for patients transitioning from an inpatient setting to home care, where the simplicity and accuracy of dosing are paramount.

While the above information outlines alternative uses for Enalapril Maleate 10 mg/ml oral liquid, it's crucial to conduct a comprehensive medication review and obtain a thorough patient history before prescribing this medication for any of these purposes. Should you have any questions or require further clarification on any aspect of the formulation's use, please do not hesitate to reach out to us at Bayview Pharmacy. Our team of compounding pharmacists is dedicated to providing the best patient care and is readily available to support both patients and prescribers in the safe and effective use of compounded medications.

Frequently Asked Questions

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What is Enalapril Maleate 10 mg/ml Oral Liquid?

Enalapril Maleate 10 mg/ml Oral Liquid is a prescription medication specifically designed for oral use. It is a liquid form of the angiotensin-converting enzyme (ACE) inhibitor Enalapril, used to treat high blood pressure, heart failure, and other conditions as prescribed by a healthcare provider. The liquid formulation is particularly beneficial for patients who have difficulties swallowing pills or tablets, including children and the elderly.

How should Enalapril Maleate Oral Liquid be stored?

This medication should be stored at room temperature, away from light and moisture. Do not store it in the bathroom, and keep it out of reach of children and pets. Always check the product label for specific storage instructions or consult your pharmacist.

What is the correct dosage of Enalapril Maleate Oral Liquid?

The dosage of Enalapril Maleate Oral Liquid can vary depending on the patient's condition, age, and response to treatment. It's crucial to follow the dosage instructions provided by your healthcare provider exactly and not to adjust your dose without their guidance.

How is Enalapril Maleate Oral Liquid taken?

Enalapril Maleate Oral Liquid should be taken as prescribed by your healthcare provider, typically once or twice a day with or without food. Measure the dose carefully using the device provided, and use the medication around the same time(s) each day to maintain an even level of the drug in your system.

Can Enalapril Maleate Oral Liquid be taken with food?

Yes, Enalapril Maleate Oral Liquid can be taken with or without food. However, it's best to take it the same way each time, either with food or on an empty stomach, as this helps maintain consistent drug levels in your bloodstream.

What should I do if I miss a dose?

If you miss a dose of Enalapril Maleate Oral Liquid, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and resume your regular dosing schedule. Do not double the dose to catch up.

Are there any side effects of Enalapril Maleate Oral Liquid?

Like any medication, Enalapril Maleate Oral Liquid can have side effects, though not everyone experiences them. Common side effects include cough, dizziness, and fatigue. More serious side effects, such as fainting or changes in the amount of urine, should be reported to your healthcare provider immediately.

Can Enalapril Maleate Oral Liquid interact with other medications?

Enalapril Maleate Oral Liquid can interact with other medications, so it is important to inform your healthcare provider of all the medications, supplements, and herbal products you are currently taking. This includes potassium supplements, diuretics, and certain pain medications like NSAIDs, among others.

Is Enalapril Maleate Oral Liquid suitable for pregnant or breastfeeding women?

Enalapril Maleate Oral Liquid is not recommended for use during pregnancy, especially in the second and third trimesters, as it may harm an unborn baby. Before taking this medication, inform your healthcare provider if you are pregnant or planning to become pregnant. Enalapril Maleate can pass into breast milk, so it's not recommended for breastfeeding mothers. Discuss the risks with your doctor.

What should I do in case of an overdose?

In the event of an overdose, seek immediate medical attention or call the Poison Help line. Symptoms of an overdose might include severe dizziness, fainting, or unusually slow or light heartbeat.

Can children and elderly patients take Enalapril Maleate Oral Liquid?

Enalapril Maleate Oral Liquid is often prescribed to children and elderly patients, as its liquid formulation is easier to swallow than pills or tablets. However, dosage for these populations should be determined by a healthcare provider, taking into account the specific needs and potential risks for each individual patient.

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Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.

No compounded medications are reviewed by the FDA for safety or efficacy.