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Licensed to fill prescriptions for patients in RI, MA, CT, NJ, NH, FL, ME and PA. New York patients are served on a limited basis while nonresident registration is pending.
Prepared to a prescriber's order for one patient. Not FDA-approved.
Doxycycline is a tetracycline-class antibiotic that compounding pharmacies prepare by prescription as oral capsules and suspensions and topical preparations.
Doxycycline is a tetracycline antibiotic. It attaches to the bacterial ribosome, the structure bacteria use to build proteins, and stops them from growing and spreading. At lower exposures it also has anti-inflammatory activity, reducing enzymes called matrix metalloproteinases and inflammatory signals in tissue. Manufactured doxycycline hyclate and monohydrate capsules, tablets and suspensions are FDA-approved for a long list of bacterial infections, including rickettsial, chlamydial and respiratory infections, tick-borne illnesses, anthrax, malaria prevention in short-term travelers and as an adjunct in severe acne; Oracea is FDA-approved for the inflammatory lesions of rosacea, and doxycycline hyclate tablets (originally Periostat) as an adjunct to scaling and root planing in adult periodontitis. A prescriber might order compounded doxycycline when a patient needs a strength or liquid that is not manufactured, a dye-free or allergen-free vehicle, or a topical form. Compounded preparations are not FDA-approved and require a prescription.
Doxycycline has no boxed warning. Its label warns that tetracyclines taken during the second half of pregnancy, infancy or childhood up to age 8 can permanently discolor teeth and slow bone growth, so young children receive it only when the benefit clearly outweighs that risk, and pregnant patients must be told of possible fetal harm. It can cause exaggerated sunburn; limit sun exposure and stop at the first sign of redness. Persistent headache or blurred or double vision can signal intracranial hypertension, a risk raised by isotretinoin, so call your prescriber right away. Watery or bloody diarrhea during or up to two months after treatment can be C. difficile infection. Antacids, calcium, magnesium, iron and bismuth block absorption; barbiturates, carbamazepine, phenytoin and rifampin lower its levels; it may increase bleeding with warfarin and should not be combined with penicillin. LactMed considers short courses acceptable while breastfeeding but not prolonged or repeated courses. Do not use it if allergic to any tetracycline. For side effects, talk to your prescriber or pharmacist.
Doxycycline is a bacteriostatic tetracycline that binds the 30S ribosomal subunit and inhibits protein synthesis; at subantimicrobial exposure it inhibits leukocyte migration, MMP activity (gelatinases A and B), TNF-alpha, IL-1 beta and nitric oxide synthase (Valentín et al., 2009). Oral absorption is virtually complete, with peak serum levels at about 2 hours, a half-life of about 18 to 22 hours unchanged in severe renal impairment or hemodialysis, variable protein binding and about 40% renal excretion over 72 hours, the remainder via bile and feces; it is highly lipophilic and distributes into skin. Labeled indications: doxycycline hyclate capsules (Hikma and others) for rickettsial, mycoplasma, chlamydial, selected gram-negative and susceptible infections, anthrax, penicillin alternatives, severe acne adjunct and P. falciparum prophylaxis; Oracea for rosacea; and doxycycline hyclate tablets (originally Periostat) as an adjunct to scaling and root planing in adult periodontitis. Subantimicrobial-dose doxycycline for rosacea is reviewed by Valentín et al. (2009) and is labeled for Oracea; use of compounded strengths, vehicles or topical forms for rosacea or acne is off-label and not described in the cited review. Dosing is per prescriber. Monitor for intracranial hypertension, photosensitivity, CDAD, severe cutaneous reactions (SJS, TEN, DRESS) and prothrombin activity in anticoagulated patients. Hyclate salts are more acidic than monohydrate and more often linked to esophageal injury. Doxycycline is not a controlled substance.
Measure each dose with the oral syringe or dosing cup provided, using the milliliter markings. Do not use household spoons. Take it by mouth as your label directs, with or without food as instructed. Rinse the measuring device after use and keep the bottle capped.
Oral solutions are aqueous. Under USP <795>, a preserved solution usually carries a beyond-use date of up to 35 days at room temperature or refrigerated, and an unpreserved one 14 days refrigerated. Your label shows whether to refrigerate and the beyond-use date. Keep out of reach of children and discard after that date.
This formulation is compounded by Bayview Pharmacy on a prescriber's order for an individual patient. It is not an FDA-approved drug product, and the FDA has not evaluated it for safety, effectiveness, or manufacturing quality.
A valid prescription is required. Availability depends on Bayview's licensure in your state. This page is general information, not medical advice. Discuss your situation with a licensed healthcare provider.
Search by NCPDP 4106882, or by name and ZIP: Bayview Pharmacy, Warwick, RI 02886. Select it as the destination pharmacy and save it as a favorite. Click any value to copy it.
Compounded preparations have no NDC, so this formula will not appear in your EHR's drug search. Use your system's compound, non-formulary, or free-text prescription entry and name the preparation exactly as written in step 3. If your EHR forces you to pick a listed drug, pick the closest entry for the active ingredient and put the full formula in the prescription body (the Sig or directions field), not in Notes to Pharmacy.
Compounded preparations have no NDC and will not appear in your drug search. For EPCS to validate, select a drug entry your EHR recognizes as controlled, usually the bulk powder entry for the active ingredient (for example Ketamine (bulk) powder, not a branded product), then put the full formula from step 3 in the prescription body. A free-text entry that does not validate as controlled will be rejected by your EPCS module.
Quantity and directions are starting points for this dose form, not treatment recommendations. Dosing remains the prescriber's responsibility.
Transmit from your EHR. For this non-controlled preparation we also accept fax to (401) 284-4506 and phoned orders at (401) 284-4505. Order forms are on the formulation pages and in the prescriber portal.
Transmit with two-factor authentication through your EPCS-enabled EHR. No order form is offered for this preparation; e-prescribing guides for our controlled preparations are on the formulation pages.
Licensed to dispense in RI, MA, CT, NJ, NH, FL, ME, and PA; New York is served on a limited basis while nonresident registration is pending. Compounded preparations are not FDA-approved. A valid prescription is required. Full guide, including steps by EHR: How to e-prescribe to Bayview. Questions about this formula: call (401) 284-4505.
Take orally
