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Clopidogrel Bisulfate 13.05 mg/5mL Gastric Tube Liquid

This formulation of Clopidogrel Bisulfate 13.05 mg/5mL Gastric Tube Liquid is a specially designed medication for administration via a gastric tube. It is primarily used in hospital settings or for patients who have difficulty swallowing. The precise and safe delivery of the drug is ensured through this method of administration.

Clopidogrel Bisulfate is an antiplatelet drug that helps prevent blood clots. It is commonly used to treat conditions such as acute coronary syndrome, myocardial infarction (heart attack), stroke, and peripheral arterial disease. By inhibiting the clumping of platelets, it aids in maintaining blood flow in the body, thereby reducing the risk of heart attacks or strokes.

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G-Tube Liquid
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Formula Information

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This formulation of Clopidogrel Bisulfate 13.05 mg/5mL Gastric Tube Liquid is a specially designed medication for administration via a gastric tube. This method of delivery ensures accurate and safe administration of the drug to patients who are unable to take oral medications. This is often the case for patients in hospital settings or those with swallowing difficulties. The formulation is designed to be easily administered through a gastric tube, reducing the risk of complications associated with other methods of administration.

Clopidogrel Bisulfate is an antiplatelet medication that works by preventing platelets in your blood from sticking together to form an unwanted blood clot that could block an artery. It is used to lower the risk of stroke, heart attack, or other heart complications in people who have heart disease, recent stroke, or blood circulation disease (peripheral vascular disease). It is also used in patients with certain disorders of the heart or blood vessels.

The dosage of Clopidogrel Bisulfate 13.05 mg/5mL Gastric Tube Liquid is determined by the prescriber based on the patient's medical condition, response to treatment, age, and other medications the patient may be taking. It is important for patients to take this medication exactly as prescribed by their healthcare provider and to continue taking it even if they feel well. Patients should also be aware that it may take up to 2 weeks before they get the full benefit of this drug.

As with any medication, Clopidogrel Bisulfate 13.05 mg/5mL Gastric Tube Liquid may cause side effects. Common side effects include bleeding, bruising, allergic reactions, and gastrointestinal issues such as stomach pain or indigestion. Patients should inform their healthcare provider if they experience any unusual or severe side effects.

It is important for prescribers to be aware of potential drug interactions with Clopidogrel Bisulfate. Certain medications, such as aspirin, nonsteroidal anti-inflammatory drugs (NSAIDs), and some antidepressants, can increase the risk of bleeding when taken with Clopidogrel. Therefore, it is crucial for prescribers to review all of a patient's medications before starting treatment with Clopidogrel Bisulfate 13.05 mg/5mL Gastric Tube Liquid.

If you have any questions about this formulation, please do not hesitate to reach out to us at Bayview Pharmacy. Our team of knowledgeable compounding pharmacists is always here to help.

Drug Interactions

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Clopidogrel Bisulfate is an antiplatelet medication that works by preventing platelets in your blood from sticking together to form an unwanted blood clot that could block an artery. It is often used to prevent heart attacks and strokes in persons with heart disease, recent stroke, or blood circulation disease (peripheral vascular disease). However, it is important to be aware of potential drug interactions when using this medication.

Concurrent use of Clopidogrel Bisulfate with other drugs that increase the risk of bleeding should be approached with caution. These include nonsteroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen and naproxen, blood thinners like warfarin, and selective serotonin reuptake inhibitors (SSRIs) such as fluoxetine and sertraline. These drugs, when taken with Clopidogrel Bisulfate, may increase the risk of bleeding.

Proton pump inhibitors (PPIs) such as omeprazole and esomeprazole should also be used with caution as they may reduce the effectiveness of Clopidogrel Bisulfate. If a patient requires a PPI, consider using one with less interaction such as pantoprazole. Similarly, drugs that inhibit the liver enzyme CYP2C19, such as fluconazole and cimetidine, can also reduce the effectiveness of Clopidogrel Bisulfate.

It's also important to note that certain other medications may have their effects increased if taken with Clopidogrel Bisulfate. These include repaglinide, a medication used to control high blood sugar in people with type 2 diabetes, and certain beta blockers like metoprolol.

Patients should be advised to avoid alcohol while taking Clopidogrel Bisulfate as it may increase the risk of stomach bleeding. They should also be aware that Clopidogrel Bisulfate can cause a serious allergic reaction. If they notice symptoms such as a rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, or trouble breathing, they should seek medical attention immediately.

It is crucial for prescribers to be aware of these potential interactions and to monitor their patients closely. They should also ensure that patients understand the importance of reporting any side effects or unusual symptoms promptly. If you have any questions about this formulation or its potential interactions, please do not hesitate to reach out to us at Bayview Pharmacy.

How Does it Work

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Clopidogrel Bisulfate 13.05 mg/5mL Gastric Tube Liquid is a specially formulated medication designed for administration via a gastric tube. This method of administration is often used in hospital settings or for patients who have difficulty swallowing. The medication is delivered directly to the stomach, bypassing the mouth and esophagus, which ensures precise and safe delivery of the drug.

The active ingredient in this formulation is clopidogrel bisulfate, a potent antiplatelet agent. It works by preventing platelets in your blood from sticking together to form unwanted blood clots, which can occur with certain heart or blood vessel conditions. By inhibiting the aggregation of platelets, clopidogrel bisulfate reduces the risk of blood clots forming, thereby preventing heart attacks and strokes.

Once administered, clopidogrel bisulfate is absorbed by the stomach and converted into its active form by enzymes in the liver. This active form then irreversibly binds to the platelet receptors, inhibiting platelet aggregation for the lifespan of the platelet, which is about 7 to 10 days. This is why the effects of clopidogrel bisulfate last for several days after the last dose is taken.

It's important to note that while clopidogrel bisulfate is effective in preventing clot-related strokes and heart attacks, it does not dissolve existing blood clots. Therefore, it is often used in combination with other medications, such as aspirin, to manage certain heart or blood vessel conditions.

As with any medication, it's crucial to use clopidogrel bisulfate as directed by a healthcare provider. The liquid formulation allows for precise dosing and is particularly beneficial for patients who have difficulty swallowing pills. However, it's important to shake the bottle well before each use to ensure the medication is evenly distributed.

Patients and prescribers should be aware of potential side effects, which can include bleeding, bruising, allergic reactions, and gastrointestinal issues. Any side effects should be reported to a healthcare provider immediately. Additionally, certain medications, including proton pump inhibitors and some antidepressants, can interact with clopidogrel bisulfate, so it's important to discuss all medications and supplements with a healthcare provider before starting treatment.

If you have any questions about Clopidogrel Bisulfate 13.05 mg/5mL Gastric Tube Liquid, please don't hesitate to reach out to us at Bayview Pharmacy. Our team of knowledgeable compounding pharmacists is here to help.

Other Uses

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While the primary use of the gastric liquid form of Clopidogrel Bisulfate is aimed towards patients who have trouble swallowing pills or cannot take oral medications, there are other beneficial applications for this drug in this particular dosage form. As a powerful antiplatelet medication, Clopidogrel Bisulfate is widely implemented in minimizing the chances of heart attacks or strokes in individuals with heart disease, recent stroke, or blood circulation disease (peripheral vascular disease).

Additionally, clinicians can consider utilizing the formulation as an advantageous strategy for specifically tailored treatment designs where continuous or intermittent drug delivery is needed, for example in long-term home care settings, nursing homes, or hospice care. As the formulation can bypass the normal process of swallowing and digestion, this can also be beneficial in certain disease states where the digestive absorption of the drug could be compromised.

Moreover, its usage can be extended to patients suffering from esophagitis, physically obstructive esophageal cancer, or following surgeries of the throat or mouth where the swallowing mechanism is temporarily or permanently impaired. This formulation could also be useful in palliative care, where ease of administration and minimal discomfort for the patient are a priority.

Lastly, it is important to note that this medication does not cure the underlying disease condition but helps in managing the symptoms and reducing the risk of serious but rare side effects like thrombotic thrombocytopenic purpura (TTP). Physicians should monitor the patients regularly and adjust the dosage according to the individual's response and side effects, if any. Please, if you have any questions regarding your medication, reach out to us at Bayview Pharmacy. We are here to help!

Frequently Asked Questions

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What is Clopidogrel Bisulfate 13.05 mg/5mL Gastric Tube Liquid?

This is a specifically formulated liquid medication containing Clopidogrel Bisulfate. It is designed for administration via a gastric tube, ensuring precise and safe delivery of the drug, especially to patients unable to take oral medications.

What medical conditions does the medication treat?

Clopidogrel Bisulfate is commonly used to prevent heart attacks, strokes, and other heart-related problems. It's especially beneficial for risk groups such as people with a recent heart attack or stroke, and those with peripheral vascular disease.

Why is it provided in liquid form?

The liquid form makes it easier to administer the medication through a gastric tube. This is particularly beneficial to patients unable to take medicines orally, or those with swallowing difficulties.

Why is the dose 13.05 mg/5mL?

This dosage is carefully calculated to provide the therapeutic benefits of Clopidogrel Bisulfate while minimizing side effects. However, the specific dose may vary depending on the patient's overall health and response to treatment.

Can it be used in home settings or only in hospitals?

While more commonly used in hospital settings, it can also be used at home under the supervision of a healthcare professional or a trained caregiver.

How is it administered via a gastric tube?

The medication is pushed gently and slowly through the gastric tube using a syringe. It's important to flush the tube with water before and after administering the medicine to ensure all medication is delivered.

What are the potential side effects?

Common side effects can include bleeding, bruising easily, and gastrointestinal problems such as diarrhoea and stomach pain. If any of these effects persist or worsen, notify the healthcare provider immediately.

Are there any precautions to take when using this medication?

It is crucial to regularly monitor the patient's response and condition while receiving the medication. Additionally, appropriate care must be taken to avoid any complications in patients with a higher risk of bleeding.

Can everyone use this medication?

Clopidogrel Bisulfate is not suitable for everyone. People with active bleeding conditions like peptic ulcers or intracranial hemorrhage, or with an allergy to Clopidogrel, should not take this medication.

What should be done if a dose is missed?

If a dose is missed, it should be taken as soon as it is remembered. However, if it is close to the time for the next dose, skip the missed dose and go back to the regular dosing schedule. Never double the dose to catch up.

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Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.

No compounded medications are reviewed by the FDA for safety or efficacy.