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Formulas

Cimetidine HCl 10%/Deoxy-D-Glucose 0.29%/Ibuprofen 2% Topical Gel

This formulation is a semisolid, gel-like consistency that is dispensed through a pump mechanism for easy and precise application on the skin. It contains Cimetidine HCl at 10%, Deoxy-D-Glucose at 0.29%, and Ibuprofen at 2%. The active ingredients are designed for targeted treatment and absorption through the skin.

Cimetidine HCl is a histamine H2-receptor antagonist that inhibits stomach acid production and is commonly used to treat gastrointestinal ulcers. Deoxy-D-Glucose is a glucose analog that interferes with glucose metabolism, and is used in diagnostic studies. Ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID) that reduces pain, inflammation, and fever.

This unique combination of ingredients in a topical gel formulation allows for targeted treatment of various disease states, including gastrointestinal disorders, inflammation, and pain management. The gel formulation allows for localized application, reducing systemic side effects and improving patient compliance.

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Topical Gel
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Formula Information

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This formulation is a unique combination of Cimetidine HCl 10%, Deoxy-D-Glucose 0.29%, and Ibuprofen 2% in a topical gel form. It is designed to be dispensed through a pump mechanism, which allows for easy and precise application on the skin. The gel-like consistency ensures that the active ingredients are absorbed effectively into the skin for targeted treatment.

Cimetidine HCl is a histamine H2-receptor antagonist. It is commonly used to treat conditions such as heartburn and peptic ulcers by reducing the amount of acid produced by the stomach. In this formulation, the topical application of Cimetidine HCl may help to reduce inflammation and irritation on the skin.

Deoxy-D-Glucose is a glucose analog that is often used in medical imaging and cancer treatment. It works by interfering with the metabolism of glucose, thereby inhibiting the growth and proliferation of cancer cells. In this topical gel, Deoxy-D-Glucose may help to target and treat skin conditions that are characterized by abnormal cell growth or proliferation.

Ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID) that is commonly used to relieve pain, reduce inflammation, and lower fever. In this formulation, the topical application of Ibuprofen may help to reduce pain and inflammation on the skin.

This formulation is designed to treat a variety of disease states. The combination of Cimetidine HCl, Deoxy-D-Glucose, and Ibuprofen may provide synergistic effects in treating conditions such as skin inflammation, pain, and conditions characterized by abnormal cell growth. However, the specific disease states that this formulation can treat will depend on the individual patient's condition and the prescriber's judgment.

As with any medication, it is important for patients and prescribers to understand the potential side effects and interactions of this formulation. Patients should inform their healthcare provider of any other medications they are currently taking, and any known allergies or adverse reactions to medications. Prescribers should monitor their patients closely for any signs of adverse reactions or side effects.

If you have any questions about this formulation, please do not hesitate to reach out to us at Bayview Pharmacy. Our team of knowledgeable compounding pharmacists is always here to help.

Drug Interactions

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Cimetidine HCl, Deoxy-D-Glucose, and Ibuprofen are the active ingredients in this topical gel formulation. Each of these ingredients has its own unique pharmacological properties and potential for drug interactions. It's important to understand these interactions to ensure safe and effective use of this medication.

Cimetidine HCl is a histamine H2-receptor antagonist, commonly used to treat conditions such as heartburn and peptic ulcers. It works by reducing the amount of acid produced by the stomach. However, Cimetidine can interact with a wide range of medications due to its ability to inhibit certain enzymes in the liver that are responsible for drug metabolism. This can lead to increased levels of these drugs in the body, potentially causing side effects or toxicity. Some of the drugs that can interact with Cimetidine include warfarin, phenytoin, theophylline, and certain antidepressants.

Deoxy-D-Glucose is a glucose analog that is often used in medical imaging and cancer treatment. It works by interfering with the metabolism of glucose in cells, which can be particularly effective in cancer cells that have a high rate of glucose metabolism. There are currently no known drug interactions with Deoxy-D-Glucose, but it's always important to inform your healthcare provider of all medications you are taking.

Ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID) that is used to relieve pain, reduce inflammation, and lower fever. It works by inhibiting the production of prostaglandins, substances in the body that cause inflammation and pain. Ibuprofen can interact with certain medications such as blood thinners, high blood pressure medications, and other NSAIDs. It can also interact with alcohol, increasing the risk of stomach bleeding.

While this formulation is designed for topical application, it's still important to consider potential drug interactions. The skin can absorb these medications, leading to systemic effects. Always inform your healthcare provider of all medications, supplements, and over-the-counter products you are using. This will help them to monitor for drug interactions and adjust your treatment plan as necessary.

This formulation is intended for targeted treatment of specific disease states. Cimetidine HCl can help to relieve symptoms of heartburn and peptic ulcers, Deoxy-D-Glucose can interfere with the metabolism of cancer cells, and Ibuprofen can reduce pain and inflammation. However, the effectiveness of this formulation will depend on the specific condition being treated and the individual patient's response to treatment.

If you have any questions about this formulation or potential drug interactions, please don't hesitate to reach out to us. We are here to provide you with the information you need to make informed decisions about your healthcare.

How Does it Work

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The Cimetidine HCl 10%/Deoxy-D-Glucose 0.29%/Ibuprofen 2% Topical Gel is a unique formulation that combines three active ingredients to provide targeted treatment for various disease states. This semisolid formulation is dispensed through a pump mechanism, which allows for easy and precise application on the skin. The gel-like consistency ensures that the active ingredients are absorbed effectively into the skin for maximum therapeutic effect.

Cimetidine HCl is a histamine H2-receptor antagonist. It works by blocking the action of histamine on the stomach cells, thereby reducing the production of stomach acid. This can help in the treatment of conditions such as gastroesophageal reflux disease (GERD) and peptic ulcers. When applied topically, Cimetidine HCl can also help in the treatment of warts by stimulating the immune system to fight the human papillomavirus (HPV), which causes warts.

Deoxy-D-Glucose is a glucose analog that is taken up by cells but cannot be metabolized. It works by inhibiting the glycolytic pathway, thereby starving the cells of energy. This can be particularly effective in the treatment of cancer cells, which rely heavily on glycolysis for their energy needs. When applied topically, Deoxy-D-Glucose can help in the treatment of skin cancers and other skin conditions.

Ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID) that works by reducing the production of prostaglandins, chemicals that cause inflammation, pain, and fever in the body. When applied topically, Ibuprofen can provide targeted relief from pain and inflammation in conditions such as arthritis, sprains, and strains.

Together, these three active ingredients provide a comprehensive treatment approach for a variety of disease states. The topical application allows for targeted treatment, reducing the risk of systemic side effects that can occur with oral medications. The pump mechanism ensures that the correct dose is applied each time, and the gel-like consistency allows for easy application and absorption of the active ingredients.

If you have any questions about this formulation or how it can benefit you, please don't hesitate to reach out to us at Bayview Pharmacy. Our knowledgeable team of compounding pharmacists is always here to help.

Other Uses

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Aside from disease-state treatments, this compounded formulation can serve additional purposes. It may be useful as a medication in therapeutic trials where treatment is experimental, or where standard medications have failed or have incited intolerable side effects. Given the components, Cimetidine HCl 10%/Deoxy-D-Glucose 0.29%/Ibuprofen 2% Topical Gel may also be utilized in pain management for conditions like localized muscle pain, joint pain, or soft tissue injuries where oral administration of pain medication is not preferred or possible. This formulation can provide localized targeted treatment, therefore potentially circumventing systemic side effects common with oral pain medications.

Cimetidine HCl, a histamine-2 blocker, may also offer potential benefits in the management of certain skin disorders, including hives and other forms of dermatitis. Its antacid properties could provide relief from discomfort caused by excess stomach acid in some patients when applied topically over the stomach area. Similarly, the component Deoxy-D-Glucose is found to have potential cancer therapeutic properties. There is experimental evidence that suggests the use of this formulation in reducing the growth of cancer cells. However, these applications are typically executed under the guidance and supervision of a healthcare provider.

Ibuprofen, a well-recognized NSAID, may also provide local relief from inflammation and pain in conditions such as arthritis, tendonitis, and other forms of inflammation. While commonly used systemically, local delivery of this anti-inflammatory can target the specific areas of discomfort, potentially reducing systemic exposure and subsequent side effects. It is worth noting that this applies to conditions where skin application is practical and the medication is able to reach its target through topical applications.

This is a general overview of some potential other uses for Cimetidine HCl 10%/Deoxy-D-Glucose 0.29%/Ibuprofen 2% Topical Gel. The specific details of use, directions, contraindications, side effects, and the feasibility would be discussed with the healthcare provider based on the individual patient's condition. For questions regarding this formulation or its potential uses, please reach out to us at Bayview Pharmacy, where our team of knowledgeable compounding pharmacists can provide detailed and personalized information.

Frequently Asked Questions

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What is the purpose of this compounded formulation?

This compounded formulation is designed for targeted treatment or absorption of active ingredients. As a topical gel, it is directly applied to the skin and provides the benefit of delivering the active compounds at the desired site, enhancing their effectiveness.

Why does this topical gel contain Cimetidine HCl, Deoxy-D-Glucose, and Ibuprofen?

Each ingredient has a specific function. Cimetidine HCl helps to reduce the production of stomach acid and is used to control conditions that require this. Deoxy-D-Glucose is a glucose analog that is used in diagnosing and treating certain diseases. Ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID) that is used to reduce inflammation and pain.

What is the right way to use this compounded formulation?

It is dispensed through a pump mechanism to facilitate easy and precise application. Apply the gel on the targeted area as directed by your healthcare practitioner.

What is the consistency of this compounded formulation?

The product is a semisolid formulation that has a gel-like consistency, ensuring it stays at the applied area for the required absorption rate.

Can this medication be used on all skin types?

Yes, typically it can be used on all skin types. However, if you have sensitive skin or known allergies, it is recommended to consult your healthcare practitioner before use.

Can I use this formulation internally or is it strictly for external use?

This is a topical gel and is strictly for external use. It must not be ingested or applied to mucous membranes or wounds.

Can this compounded formulation cause side effects?

Most topical medications have few side effects, but some people may experience skin reactions like redness, itchiness or rash. If these symptoms persist or worsen, contact your healthcare provider immediately.

Are there any storage instructions for this topical gel?

It is important to store this medication away from heat, light, and moisture, preferably in a cool and dry place. Always ensure the cap is tightly closed after use.

What do I do in case of an overdose?

Since this is a topical gel, the likelihood of an overdose is minimal. However, if you accidentally apply more than directed and develop severe skin reactions, contact your healthcare provider immediately.

Will this formulation interact with other medications?

There may be potential interactions with other topical products that you are using. It is always advisable to inform your healthcare provider of any other medications or skincare products you are using concurrently.

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Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.

No compounded medications are reviewed by the FDA for safety or efficacy.