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Formulas

Brompheniramine Maleate 2 mg/5 mL Oral Syrup

Brompheniramine Maleate 2 mg/5 mL Oral Syrup is a concentrated liquid formulation designed for oral administration. It contains active ingredients and sweeteners, providing a palatable and easy-to-administer dosage form. This syrup is particularly beneficial for pediatric patients or individuals who have difficulty swallowing tablets or capsules.

This formulation is used to treat symptoms associated with allergic rhinitis, such as sneezing, runny nose, and itchy or watery eyes. It is also effective in managing symptoms of the common cold, including nasal congestion and cough.

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Brompheniramine Maleate
Oral Syrup
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Formula Information

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Brompheniramine Maleate 2 mg/5 mL Oral Syrup is an antihistamine medication formulated in a concentrated liquid form, designed for ease of administration and enhanced palatability. This syrup contains sweeteners to improve taste, making it particularly suitable for pediatric patients or individuals who have difficulty swallowing tablets or capsules. The liquid formulation allows for precise dosing adjustments, which is essential for tailoring treatment to individual patient needs.

Brompheniramine Maleate works by blocking histamine H1 receptors, thereby inhibiting the action of histamine—a substance in the body that causes allergic symptoms. This medication is effective in relieving symptoms associated with allergic reactions such as sneezing, itchy and watery eyes, runny nose, and throat irritation. It is commonly used in the management of allergic rhinitis, hay fever, and other upper respiratory allergies.

For prescribers, this syrup offers flexibility in dosing and administration, which is crucial when treating young children or patients with swallowing difficulties. The 2 mg/5 mL concentration allows for easy calculation of the appropriate dose based on the patient’s age, weight, and severity of symptoms. It is important to assess the patient’s medical history for any contraindications such as hypersensitivity to antihistamines or presence of narrow-angle glaucoma, urinary retention, or severe hypertension.

Patients taking Brompheniramine Maleate Oral Syrup should be advised on the potential side effects, which may include drowsiness, dizziness, dry mouth, blurred vision, or gastrointestinal disturbances. Caution is recommended when performing tasks that require alertness, such as driving or operating machinery, especially at the initiation of therapy. Alcohol and other central nervous system depressants may enhance the sedative effects of brompheniramine and should be avoided.

If symptoms persist or worsen despite treatment, patients should consult their healthcare provider for further evaluation. Regular monitoring may be necessary for prolonged use to ensure efficacy and safety. It is also advisable to discuss any other medications or supplements being taken to avoid potential drug interactions.

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Drug Interactions

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Brompheniramine Maleate 2 mg/5 mL Oral Syrup is an antihistamine used to relieve symptoms of allergy, hay fever, and the common cold. These symptoms may include rash, watery eyes, itchy eyes/nose/throat/skin, cough, runny nose, and sneezing. As with any medication, it is important to be aware of potential drug interactions that may affect the efficacy and safety of Brompheniramine Maleate.

Concomitant use of Brompheniramine Maleate with other central nervous system (CNS) depressants, such as alcohol, benzodiazepines, opioids, and certain antidepressants, can enhance the sedative effects of these drugs. This can lead to increased drowsiness, dizziness, and impaired cognitive and motor function. Patients should be advised to avoid or limit the use of alcohol and consult their healthcare provider before using other CNS depressants while taking this medication.

Monoamine oxidase inhibitors (MAOIs), which are used to treat depression and other psychiatric disorders, can interact with Brompheniramine Maleate, potentially leading to an increase in the anticholinergic and sedative effects. Patients should not use Brompheniramine Maleate if they have taken an MAOI within the past 14 days. If a patient is currently on an MAOI, they should consult their healthcare provider before starting Brompheniramine Maleate.

Anticholinergic drugs, such as atropine, scopolamine, and certain medications for Parkinson's disease, can have additive effects when used with Brompheniramine Maleate, leading to increased risk of side effects such as dry mouth, constipation, urinary retention, and blurred vision. Patients should be monitored for these side effects and consult their healthcare provider if they experience any adverse reactions.

Patients taking medications that affect the cytochrome P450 enzyme system, particularly CYP2D6 inhibitors, should be aware that these drugs can alter the metabolism of Brompheniramine Maleate, potentially leading to increased plasma concentrations and enhanced effects. Healthcare providers should assess the patient's medication regimen for potential interactions and adjust dosages as necessary.

In addition to these interactions, patients with pre-existing conditions such as glaucoma, peptic ulcer, prostatic hypertrophy, or bladder neck obstruction should use Brompheniramine Maleate with caution, as the anticholinergic effects may exacerbate these conditions. It is crucial for prescribers to evaluate the patient's medical history and current medications to ensure the safe use of Brompheniramine Maleate.

If you have any questions or concerns about drug interactions with Brompheniramine Maleate 2 mg/5 mL Oral Syrup, please reach out to us for further assistance. Our team of compounding pharmacists at Bayview Pharmacy is here to provide you with the information and support you need to ensure safe and effective medication use.

How Does it Work

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Brompheniramine Maleate 2 mg/5 mL Oral Syrup is a concentrated liquid formulation specifically designed to deliver the active ingredient, brompheniramine maleate, in a palatable and easy-to-administer form. This formulation is particularly beneficial for pediatric patients or individuals who have difficulty swallowing tablets or capsules. Brompheniramine maleate is an antihistamine that works by blocking the action of histamine, a substance in the body that causes allergic symptoms. By inhibiting histamine receptors, brompheniramine maleate effectively reduces symptoms such as sneezing, itching, watery eyes, and runny nose, which are commonly associated with allergic reactions and the common cold.

The syrup form of brompheniramine maleate ensures that the medication is evenly distributed throughout the liquid, allowing for precise dosing. This is especially important in pediatric care, where accurate dosing is crucial to ensure both efficacy and safety. The sweeteners included in the formulation enhance the taste, making it more acceptable for children and those sensitive to the taste of medications. The liquid form also allows for flexibility in dosing, as it can be easily measured to provide the exact dose required for each individual patient, based on their specific needs and the severity of their symptoms.

For prescribers, this formulation offers a reliable option for managing allergic symptoms in patients who may not tolerate solid dosage forms. The pharmacokinetics of brompheniramine maleate in liquid form allow for rapid absorption and onset of action, providing timely relief from discomfort. Additionally, the syrup can be administered with or without food, offering convenience and ease of use in various settings. It is important for prescribers to consider the patient's age, weight, and medical history when determining the appropriate dosage and to monitor for any potential side effects, such as drowsiness or dry mouth, which are common with antihistamines.

Patients and caregivers should be advised on the correct method of measuring and administering the syrup to ensure accurate dosing. It is recommended to use a proper measuring device, such as an oral syringe or a dosing cup, rather than household spoons, to avoid dosing errors. Patients should also be informed about the potential side effects and advised to avoid activities that require alertness, such as driving, until they know how the medication affects them. If there are any questions or concerns regarding the use of Brompheniramine Maleate 2 mg/5 mL Oral Syrup, please reach out to us at Bayview Pharmacy for further assistance and guidance.

Other Uses

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Brompheniramine Maleate 2 mg/5 mL Oral Syrup is primarily used as an antihistamine for the relief of symptoms associated with allergic rhinitis, such as sneezing, runny nose, itchy or watery eyes, and itching of the nose or throat. However, this formulation can also be utilized for other purposes beyond its primary indication. Due to its antihistaminic properties, it may be employed off-label for the management of symptoms related to the common cold, although it is important to note that it does not cure or shorten the duration of the cold. Additionally, Brompheniramine Maleate can be used to alleviate symptoms of allergic conjunctivitis and other mild allergic reactions, providing relief from discomfort and irritation.

In certain cases, this oral syrup may be considered for use in managing mild cases of urticaria (hives) or as an adjunct therapy in more complex allergic conditions, where its sedative effects can also aid in improving sleep disturbances caused by itching. The liquid formulation is particularly beneficial for pediatric patients or adults who have difficulty swallowing pills, ensuring that they receive the appropriate dosage in a palatable and easy-to-administer form. This makes it a versatile option for patients with varying needs, including those with dysphagia or other swallowing disorders.

For prescribers, it is crucial to consider the patient's overall medication regimen and potential interactions, as Brompheniramine Maleate can cause drowsiness and may enhance the effects of other central nervous system depressants. Patients should be advised to avoid alcohol and be cautious when engaging in activities that require mental alertness, such as driving or operating machinery. As with any medication, the benefits and risks should be carefully weighed, and the use of this syrup should be tailored to the individual patient's needs and medical history.

If you have any questions or require further information about the use of Brompheniramine Maleate 2 mg/5 mL Oral Syrup, please reach out to us at Bayview Pharmacy. Our team of compounding pharmacists is here to assist you with any inquiries or concerns you may have regarding this formulation or its applications.

Frequently Asked Questions

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What is Brompheniramine Maleate 2 mg/5 mL Oral Syrup used for?

Brompheniramine Maleate 2 mg/5 mL Oral Syrup is an antihistamine used to relieve symptoms of allergy, hay fever, and the common cold, such as runny nose, sneezing, itching, and watery eyes.

How should I take Brompheniramine Maleate Oral Syrup?

This syrup should be taken by mouth, usually every 4 to 6 hours, or as directed by your healthcare provider. Use a proper measuring device to ensure the correct dose.

Is Brompheniramine Maleate Oral Syrup suitable for children?

Yes, this formulation is often used in pediatric populations due to its palatable taste and ease of administration. However, always consult a healthcare provider for appropriate dosing in children.

Can I take Brompheniramine Maleate Oral Syrup if I am pregnant or breastfeeding?

If you are pregnant or breastfeeding, consult your healthcare provider before using this medication to ensure it is safe for you and your baby.

What should I do if I miss a dose of Brompheniramine Maleate Oral Syrup?

If you miss a dose, take it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up.

What are the possible side effects of Brompheniramine Maleate Oral Syrup?

Common side effects include drowsiness, dizziness, dry mouth, and blurred vision. If you experience severe side effects such as difficulty breathing or swelling, seek medical attention immediately.

Can I drive or operate machinery after taking Brompheniramine Maleate Oral Syrup?

This medication may cause drowsiness or dizziness. Avoid driving or operating heavy machinery until you know how the medication affects you.

Are there any interactions with other medications I should be aware of?

Brompheniramine Maleate may interact with other medications, such as sedatives, tranquilizers, and certain antidepressants. Inform your healthcare provider of all medications you are taking to avoid potential interactions.

How should I store Brompheniramine Maleate Oral Syrup?

Store the syrup at room temperature, away from light and moisture. Keep it out of reach of children and pets.

What should I do in case of an overdose?

If an overdose is suspected, seek emergency medical attention immediately. Symptoms of overdose may include severe drowsiness, seizures, or difficulty breathing.

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Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.

No compounded medications are reviewed by the FDA for safety or efficacy.