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Formulas

Betamethasone Dipropionate 0.032%/Clotrimazole 2.5%/Mupirocin 0.5%/Nystatin 25/000 IU/g Topical Ointment

This formulation is a semi-solid topical ointment containing Betamethasone Dipropionate 0.032%, Clotrimazole 2.5%, Mupirocin 0.5%, and Nystatin 25,000 IU/g. It is dispensed in a tube and is designed for external application to the skin. The greasy or oily base of the ointment aids in the delivery of the medication, providing localized treatment.

The ointment is used to treat a variety of disease states. Betamethasone Dipropionate is a potent corticosteroid that reduces inflammation, itching, and redness. Clotrimazole is an antifungal agent used to treat skin infections such as athlete's foot, jock itch, and ringworm. Mupirocin is an antibiotic that prevents bacteria from growing on your skin, used for treating skin infections such as impetigo. Nystatin is an antifungal medication that fights infections caused by fungus, used for treating skin infections such as candidiasis.

Together, these active ingredients work to treat conditions such as skin inflammation, infections, and aid in wound healing. The formulation is designed to provide relief from symptoms and promote healing in the affected areas.

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Topical Ointment
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Formula Information

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This formulation is a combination of four active ingredients: Betamethasone Dipropionate, Clotrimazole, Mupirocin, and Nystatin, each serving a unique therapeutic purpose. It is a semi-solid topical ointment designed for external application to the skin. The greasy or oily base of the ointment aids in the delivery of these medications, providing localized treatment for a variety of skin conditions.

Betamethasone Dipropionate is a potent corticosteroid that works by reducing inflammation, redness, and itching. This makes it particularly effective in treating various skin conditions such as eczema, dermatitis, allergies, and rash. Its concentration in this formulation is 0.032%, which is a typical dose for topical corticosteroids.

Clotrimazole, present at a concentration of 2.5%, is an antifungal medication. It works by stopping the growth of fungus, making it effective in treating skin infections such as ringworm, athlete's foot, and jock itch. It can also be used to treat yeast infections of the skin.

Mupirocin, at a concentration of 0.5%, is an antibiotic that prevents bacteria from growing on your skin. It is used to treat skin infections such as impetigo or folliculitis, and can also be used to prevent the spread of certain skin infections.

Nystatin, present at a concentration of 25,000 IU/g, is an antifungal medication that works by stopping the growth of fungus. It is used to treat skin infections caused by yeast, including candidiasis.

This combination of ingredients makes the formulation a versatile treatment option for a variety of skin conditions, including inflammation, infections, and wound healing. It is important to use this medication as directed by your healthcare provider, and to complete the full course of treatment, even if symptoms improve before the medication is finished.

As with any medication, this formulation may cause side effects, including burning, stinging, redness, or irritation at the application site. If these effects persist or worsen, or if you experience any serious side effects such as stretch marks, skin thinning/discoloration, or unusual hair growth, contact your healthcare provider immediately.

For any questions or concerns regarding this formulation, please do not hesitate to reach out to us at Bayview Pharmacy. Our team of knowledgeable compounding pharmacists is here to assist you.

Drug Interactions

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This formulation combines four active ingredients: Betamethasone Dipropionate, Clotrimazole, Mupirocin, and Nystatin. Each of these ingredients has a specific role in treating various skin conditions. Betamethasone Dipropionate is a potent corticosteroid that reduces inflammation, itching, and redness. Clotrimazole is an antifungal medication used to treat skin infections such as athlete's foot, jock itch, and ringworm. Mupirocin is an antibiotic that prevents bacteria from growing on your skin. Nystatin is an antifungal medication that fights infections caused by fungus.

While this formulation is designed to treat a variety of skin conditions, it's important to be aware of potential drug interactions. If you're taking other medications, particularly other topical treatments, it's crucial to inform your healthcare provider to avoid potential interactions.

For instance, using other corticosteroids alongside Betamethasone Dipropionate may increase the risk of side effects such as skin thinning. Similarly, using other topical antibiotics with Mupirocin could potentially increase the risk of antibiotic resistance. If you're using other antifungal medications alongside Clotrimazole or Nystatin, it could potentially reduce the effectiveness of these medications.

Furthermore, this formulation should not be used with certain medications due to the potential for increased absorption through the skin and into the bloodstream, which could lead to systemic side effects. These medications include, but are not limited to, certain diuretics (such as hydrochlorothiazide), medications for diabetes (such as glyburide), and certain heart medications (such as digoxin).

It's also important to note that this formulation should not be used on large areas of skin, in deep or puncture wounds, on animal bites, or on serious burns, unless directed by a healthcare provider. Doing so could increase the risk of absorption into the bloodstream and lead to systemic side effects.

Always inform your healthcare provider of all the medications you're currently taking, including prescription and over-the-counter drugs, vitamins, and herbal supplements. This will help your healthcare provider to monitor for drug interactions and manage them appropriately.

If you have any questions or concerns about this formulation or potential drug interactions, please don't hesitate to reach out to us at Bayview Pharmacy. Our team of knowledgeable compounding pharmacists is here to assist you.

How Does it Work

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This formulation is a combination of four active ingredients: Betamethasone Dipropionate, Clotrimazole, Mupirocin, and Nystatin. Each of these ingredients plays a crucial role in treating various skin conditions.

Betamethasone Dipropionate is a potent corticosteroid that works by reducing inflammation, redness, and itching. It does this by suppressing the immune response, which reduces the release of chemicals in the body that cause inflammation. This makes it particularly effective in treating conditions such as eczema and psoriasis.

Clotrimazole is an antifungal medication that works by inhibiting the growth of fungus. It does this by interfering with the production of the fungal cell membrane, which results in the death of the fungus. This makes it effective in treating skin conditions caused by fungus, such as athlete's foot, jock itch, and ringworm.

Mupirocin is an antibiotic that works by stopping the growth of certain bacteria. It does this by inhibiting the production of certain proteins necessary for the bacteria to survive. This makes it effective in treating skin infections caused by bacteria, such as impetigo.

Nystatin is another antifungal medication that works by binding to sterols in the fungal cell membrane, which changes the cell wall permeability causing the contents of the cell to leak out. This makes it effective in treating skin infections caused by yeast, such as candidiasis.

The semi-solid formulation of this medication is designed for external application to the skin. The greasy or oily base aids in the delivery of the medication, allowing it to penetrate the skin and provide localized treatment. This makes it particularly effective for conditions that affect the skin, as it allows for direct application to the affected area.

It's important to note that while this formulation can be highly effective in treating a variety of skin conditions, it should only be used under the direction of a healthcare provider. Overuse or misuse of this medication can lead to side effects such as skin thinning, irritation, or resistance to the medication.

If you have any questions about this formulation, don't hesitate to reach out to us at Bayview Pharmacy. Our team of knowledgeable compounding pharmacists is here to help.

Other Uses

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This potent combination of Betamethasone Dipropionate, Clotrimazole, Mupirocin, and Nystatin in a topical ointment formulates a broad-spectrum treatment used primarily to manage various conditions such as skin inflammations, infections, and wounds. However, its components' properties give it potential for several other uses not initially foreseen.

Due to the anti-inflammatory property of Betamethasone Dipropionate, this formulation may extend to conditions characterized by inflammation and itching - such as eczema, psoriasis, or dermatitis. The steroid component can decrease swelling, redness, and itching that these conditions often cause. It bears noting, though, that it should be adopted on the advice of a healthcare provider as extended use has the potential for side-effects, including skin thinning.

Similarly, the antifungal properties of the Clotrimazole and Nystatin in this formulation make it potentially suitable for managing certain fungal infections on the body that are not initially apparent. These may include infections that present with symptoms such as scaling, itching, and burning sensations. It's crucial to note that patients who suspect they may have a fungal infection should seek professional advice before applying any topical medications.

The antimicrobial ingredient, Mupirocin, can aid in preventing bacterial skin infections or treating small skin cuts, nicks, or scrapes to forestall any potential infections. It is beneficial for minor skin abrasions or even burns but should not be used for prolonged periods without supervision due to the potential for bacterial resistance.

The inclusion of all these compounds in one formulation provides a broad-spectrum solution for several skin conditions, enhancing patient convenience and alleviating the necessity for several separate medications. However, use for other unintended conditions should always be under the guidance of healthcare professionals. Given its potency, potential side-effects and contraindications should also be closely monitored.

If you have further questions about this formulation, the indications, and how it can be beneficial for various skin conditions, please don't hesitate to reach out to us. As experienced compounding pharmacists at Bayview Pharmacy, we are more than ready to address any concerns from patients and prescribers about this product.

Frequently Asked Questions

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What is the Betamethasone Dipropionate/Clotrimazole/Mupirocin/Nystatin Topical Ointment?

It's a semi-solid formulation designed for external application to the skin. The ointment aids in the delivery of medication or therapeutic agents for localized treatment. It's typically used for conditions such as skin inflammation, infections, or wound healing.

How should the ointment be applied?

The ointment should be applied on the affected area of the skin, as directed by a healthcare professional or as instructed on the packaging. Always wash and dry your hands before and after application.

Is the ointment suitable for all skin types?

This medication is usually safe for all skin types. However, in case of sensitive skin or allergies, it's advisable to discuss this with a healthcare professional before starting the treatment.

What are the main ingredients in the ointment?

The main ingredients in this ointment are Betamethasone Dipropionate 0.032%, Clotrimazole 2.5%, Mupirocin 0.5%, and Nystatin 25,000 IU/g.

Can this ointment be used for diaper rash?

This is a prescription medication, and it's crucial to use it according to the specific prescription. Do not use it on diaper rash or any condition without the recommendation and supervision of a healthcare professional.

Can I use it if I'm pregnant or breastfeeding?

If you are pregnant, planning to get pregnant, or breastfeeding, discuss this with your healthcare provider before starting the treatment as it may have potential risks.

What should I do if I experience any side effects?

If you experience any adverse effects such as skin rash, redness, itching or any other unusual symptoms, stop using the product and consult your healthcare provider immediately.

How should I store the ointment?

Keep the product at room temperature, away from heat and light. Make sure it is out of the reach of children and pets.

Can I use this ointment after the expiration date?

No, do not use the ointment past the expiration date printed on the tube. The effectiveness of the product may be diminished past this date.

Who can use this ointment?

This compounded formulation is a prescription medication, so it should be used by the person for whom it was prescribed, and as directed by a healthcare professional.

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Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.

No compounded medications are reviewed by the FDA for safety or efficacy.