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Baclofen 3%/Ketamine HCl 3%/Ketoprofen 20% Transdermal Gel

This formulation is a Baclofen 3%/Ketamine HCl 3%/Ketoprofen 20% Transdermal Gel. It is a semisolid formulation dispensed through a pump mechanism, which allows for easy and precise application on the skin. The gel-like consistency ensures targeted treatment or absorption of the active ingredients. The formulation is designed to treat a variety of disease states, including muscle spasms, chronic pain, and inflammation. The combination of Baclofen, a muscle relaxant, Ketamine HCl, a potent analgesic, and Ketoprofen, a nonsteroidal anti-inflammatory drug, provides a comprehensive approach to managing these conditions.

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Ketamine Hydrochloride
Ketoprofen
Baclofen
Topical Gel
6535d390db50a4a1c6b9005b
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Formula Information

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This formulation combines Baclofen, Ketamine HCl, and Ketoprofen in a transdermal gel, designed to be easily applied to the skin for targeted treatment. The gel is dispensed through a pump mechanism, ensuring precise application and facilitating absorption of the active ingredients.

Baclofen is a muscle relaxant and antispastic agent. It works by restoring the normal transmission of nerve signals in certain parts of the brain. This can help to reduce muscle spasms and tightness, often associated with conditions such as multiple sclerosis or spinal cord injuries.

Ketamine HCl is a potent analgesic that works by blocking certain receptors in the brain that are responsible for transmitting pain signals. This can provide significant relief from chronic pain conditions, including neuropathic pain, fibromyalgia, and complex regional pain syndrome (CRPS).

Ketoprofen is a nonsteroidal anti-inflammatory drug (NSAID) that works by reducing hormones that cause inflammation and pain in the body. It is commonly used to relieve pain, swelling, and joint stiffness caused by arthritis.

By combining these three active ingredients in a transdermal gel, this formulation provides targeted relief from pain and muscle spasms directly at the site of application. The gel-like consistency allows for easy and precise application, while the transdermal delivery ensures that the active ingredients are absorbed directly into the affected area, providing fast and effective relief.

This formulation is typically used for the management of conditions such as neuropathic pain, fibromyalgia, CRPS, arthritis, and muscle spasms associated with neurological conditions. It is important to note that this medication should be used as directed by a healthcare provider, and patients should report any side effects or concerns immediately.

If you have any questions about this formulation, or if you would like more information on how it can be used to treat specific conditions, please do not hesitate to reach out to us at Bayview Pharmacy. Our team of knowledgeable compounding pharmacists is always here to help.

Drug Interactions

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This formulation contains Baclofen, Ketamine HCl, and Ketoprofen, all of which can interact with other medications. It's important to inform your healthcare provider about all the medications you're currently taking, including prescription and over-the-counter drugs, vitamins, and herbal supplements.

Baclofen, a muscle relaxant and antispastic agent, can interact with other central nervous system depressants like alcohol, benzodiazepines, and opioids, potentially leading to increased sedation and respiratory depression. It can also interact with antihypertensive drugs, potentially enhancing their effects and causing hypotension.

Ketamine HCl, an NMDA receptor antagonist, can interact with other CNS depressants, potentially leading to increased sedation and respiratory depression. It can also interact with monoamine oxidase inhibitors (MAOIs), potentially leading to a hypertensive crisis. Furthermore, it can interact with drugs that affect the serotonin system, such as selective serotonin reuptake inhibitors (SSRIs) and serotonin and norepinephrine reuptake inhibitors (SNRIs), potentially leading to serotonin syndrome.

Ketoprofen, a nonsteroidal anti-inflammatory drug (NSAID), can interact with anticoagulants and antiplatelet drugs, potentially increasing the risk of bleeding. It can also interact with other NSAIDs, potentially increasing the risk of gastrointestinal bleeding. Furthermore, it can interact with angiotensin-converting enzyme (ACE) inhibitors, angiotensin II receptor blockers (ARBs), and beta-blockers, potentially reducing their antihypertensive effects. It can also interact with diuretics, potentially reducing their diuretic effects and leading to renal failure in susceptible individuals.

This formulation is used for targeted treatment or absorption of active ingredients in a gel-like consistency. It's typically used for conditions that involve pain and inflammation, such as arthritis, and conditions that involve muscle spasticity, such as multiple sclerosis. Baclofen helps to relieve muscle spasticity, Ketamine HCl helps to relieve pain, and Ketoprofen helps to relieve pain and inflammation.

If you have any questions about this formulation or its potential drug interactions, please don't hesitate to reach out to us. We're here to help you understand your medications and use them safely and effectively.

How Does it Work

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The Baclofen 3%/Ketamine HCl 3%/Ketoprofen 20% Transdermal Gel is a unique formulation that combines three active ingredients, each with its own mechanism of action, to provide targeted relief from various disease states. This formulation is designed to be applied topically, directly to the skin, where it is absorbed into the body to exert its therapeutic effects.

Baclofen is a muscle relaxant and an antispastic agent. It works by restoring the normal transmission of nerve signals in certain parts of the brain. This helps to reduce muscle spasms, tightness, and pain. In this formulation, baclofen is used to alleviate symptoms associated with conditions like multiple sclerosis and spinal cord injuries.

Ketamine HCl, on the other hand, is a potent analgesic. It works by blocking the NMDA receptors in the brain and spinal cord, which play a key role in transmitting pain signals. By blocking these receptors, ketamine can effectively reduce pain and discomfort. It is often used in the management of chronic pain conditions, including neuropathic pain and fibromyalgia.

Ketoprofen is a nonsteroidal anti-inflammatory drug (NSAID). It works by reducing the production of prostaglandins, chemicals that cause inflammation, pain, and fever in the body. Ketoprofen is used to relieve pain, reduce inflammation, and lower fever. It is commonly used in conditions like arthritis, gout, and other inflammatory diseases.

The transdermal gel formulation allows for targeted application and absorption of these active ingredients. The gel is dispensed through a pump mechanism, which facilitates easy and precise application. Once applied to the skin, the active ingredients are absorbed into the body where they exert their therapeutic effects. This targeted approach helps to maximize the therapeutic benefits while minimizing potential side effects.

It's important to note that while this formulation can provide significant relief from various disease states, it should be used under the guidance of a healthcare provider. Always follow the prescribed dosage and application instructions to ensure the safe and effective use of this medication.

If you have any questions about the Baclofen 3%/Ketamine HCl 3%/Ketoprofen 20% Transdermal Gel, please don't hesitate to reach out to us at Bayview Pharmacy. Our team of knowledgeable compounding pharmacists is always here to help.

Other Uses

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Baclofen, Ketamine Hcl, and Ketoprofen in a transdermal gel formulation are primarily used to treat neuropathic pain and the painful symptoms of several conditions such as Complex Regional Pain Syndrome, arthritis, and nerve-related pain. The compounded formulation provides the benefit of transdermal absorption, offering targeted relief directly to the pain site without flooding the whole body with medication. This can minimize the potential for systemic side effects and the drug-drug interactions associated with systemic delivery.

Other potential uses for this formulation include managing postherpetic neuralgia (pain following shingles), fibromyalgia, or phantom limb pain. Baclofen works as a muscle relaxant and anti-spastic agent and is therefore beneficial in treating muscle twitching and stiffness. Ketoprofen, as an NSAID, contributes to relieving pain, reducing inflammation and swelling. Meanwhile, ketamine aids in pain management due to its NMDA antagonist effects. By combining these three medications in a transdermal gel, it delivers pain relief directly to the required zone while maintaining a low systemic concentration to potentially decrease side effects.

This application is also youthfully appropriate for patients who cannot swallow pills or who experience gastrointestinal complications from oral medications. Nevertheless, always remember that these uses are at the discretion of a qualified healthcare professional, who will assess the patient's overall condition, current medications, and potential risks before prescribing to ensure maximum efficacy and safety.

Please consult with your healthcare provider before initiating any new treatment. For any additional questions or concerns, do not hesitate to reach out to us here at Bayview Pharmacy. Our knowledgeable compounding pharmacists team is always ready to provide you with the necessary guidance and support.

Frequently Asked Questions

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What is Baclofen 3%/Ketamine HCl 3%/Ketoprofen 20% Transdermal Gel?

This is a compounded medication that combines the active ingredients Baclofen, Ketamine HCl, and Ketoprofen in a gel-like consistency. The medicine is dispensed through a pump mechanism, making it easy to apply to the skin for targeted treatment.

What is the purpose of the active ingredients in the formulation?

Baclofen is a muscle relaxant and anti-spastic agent, Ketamine HCl serves as an anesthetic, and Ketoprofen is a nonsteroidal anti-inflammatory drug (NSAID). Combined, these ingredients can provide potent, localized relief from various discomforts.

How do I apply Baclofen 3%/Ketamine HCl 3%/Ketoprofen 20% Transdermal Gel?

This medication is designed to be topically applied to the skin. Ensure the skin is clean and gently apply a thin layer to the affected area as directed by your healthcare professional.

What makes a transdermal gel different from other forms of medication delivery?

Transdermal gels are applied directly to the skin where they are absorbed into the body. They allow for targeted treatment, as you can apply the medication exactly where it's needed. This method can offer faster and more effective relief in some cases.

What precautions should I take when using this compounded formulation?

Avoid contact with eyes, nose, mouth, and other sensitive areas when applying the gel. If the medication accidentally gets in these areas, rinse it out immediately with water. Only use the gel on the skin and do not ingest it.

Are there any potential side effects of this formulation?

As with any medication, there can be side effects. These might include local skin irritation or allergic reactions. If you notice any adverse reactions, contact your healthcare provider immediately.

How should I store this medication?

Store your gel in a cool, dry place away from sunlight. Always ensure the cap is properly closed to prevent the medication from drying out.

Can I use this formulation with other medications?

It is important to inform your healthcare provider of all medications you are currently taking, including over-the-counter drugs and supplements. They can advise whether it is safe to use this gel alongside other treatments.

What should I do if I miss a dose?

If you miss a dose, apply it as soon as you remember. However, if it's close to the time for your next dose, skip the missed one and apply the gel at the next scheduled time. Don't use extra gel to make up for the missed dose.

Is this formulation suitable for all ages?

The suitability of this medication for people of different ages depends on the individual's health condition and other factors. Always seek advice from a healthcare professional. It's important not to use this medication in children or adults if not directed by a physician.

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Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.

No compounded medications are reviewed by the FDA for safety or efficacy.