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Baclofen 2%/Gabapentin 6%/Ketoprofen 6%/Lidocaine 2%/Prilocaine 2% Topical Gel

This formulation is a compounded topical gel containing Baclofen 2%, Gabapentin 6%, Ketoprofen 6%, Lidocaine 2%, and Prilocaine 2%. It is a semisolid formulation dispensed through a pump mechanism, which allows for easy and precise application on the skin. The gel-like consistency ensures targeted treatment or absorption of the active ingredients.

The combination of these active ingredients is designed to treat a variety of disease states. Baclofen is a muscle relaxant and antispasmodic agent used to relieve spasms, pain, and stiffness. Gabapentin is an anticonvulsant and nerve pain medication used to treat seizures and pain caused by shingles. Ketoprofen is a nonsteroidal anti-inflammatory drug (NSAID) used to relieve pain, swelling, and joint stiffness caused by arthritis. Lidocaine and Prilocaine are local anesthetics used to numb the skin or surfaces of the body to prevent pain and discomfort during medical procedures.

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Topical Gel
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Formula Information

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This formulation is a compounded topical gel containing Baclofen 2%, Gabapentin 6%, Ketoprofen 6%, Lidocaine 2%, and Prilocaine 2%. It is a semisolid formulation dispensed through a pump mechanism, which allows for easy and precise application on the skin. The gel-like consistency ensures that the active ingredients are absorbed effectively into the targeted area for optimal therapeutic effect.

Baclofen is a muscle relaxant and antispastic agent that helps to relieve muscle spasms, tightness, and pain. Gabapentin is an anticonvulsant and nerve pain medication that is often used to treat nerve pain conditions. Ketoprofen is a nonsteroidal anti-inflammatory drug (NSAID) that reduces inflammation and pain in the body. Lidocaine and Prilocaine are local anesthetics that work by causing temporary numbness/loss of feeling in the skin and mucous membranes. This combination of medications in the formulation works synergistically to provide pain relief, reduce inflammation, and alleviate muscle spasms.

This formulation can be used to treat a variety of disease states. It is particularly effective in managing conditions such as neuropathic pain, fibromyalgia, post-herpetic neuralgia, and other conditions where inflammation, nerve pain, and muscle spasms are present. It can also be used in the management of localized pain conditions, such as arthritis or sports injuries, where the application of the gel can provide targeted relief.

It is important to note that this is a compounded medication, meaning it is made specifically for the patient based on a doctor's prescription. The strength and combination of the medications can be adjusted to meet the specific needs of the patient. As with any medication, it is important to use this formulation as directed by your healthcare provider. Side effects can occur and should be reported to your healthcare provider immediately.

If you have any questions about this formulation, its uses, or how it can benefit you, please do not hesitate to reach out to us at Bayview Pharmacy. Our team of knowledgeable compounding pharmacists is here to assist you.

Drug Interactions

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This compounded formulation contains Baclofen, Gabapentin, Ketoprofen, Lidocaine, and Prilocaine. Each of these active ingredients has its own potential for drug interactions, which can be amplified when used in combination. It's important to consider these interactions when prescribing or using this medication.

Baclofen is a muscle relaxant and antispastic agent. It may interact with other central nervous system depressants like alcohol, benzodiazepines, opioids, and antihistamines, potentially leading to increased sedation or respiratory depression. Concurrent use with monoamine oxidase inhibitors (MAOIs) may result in hypotension.

Gabapentin, an anticonvulsant and nerve pain medication, may have its absorption rate affected by antacids. It's recommended to take gabapentin at least 2 hours after taking an antacid. Gabapentin may also increase the effects of other drugs that cause sedation, including opioids, antihistamines, and alcohol.

Ketoprofen, a nonsteroidal anti-inflammatory drug (NSAID), may interact with anticoagulants, increasing the risk of bleeding. It may also interact with other NSAIDs, corticosteroids, or alcohol, increasing the risk of gastrointestinal ulcers or bleeding. Ketoprofen may reduce the effectiveness of certain blood pressure medications and may increase the levels of lithium or methotrexate in the body.

Lidocaine and Prilocaine are local anesthetics. They have fewer systemic interactions, but may interact with other local anesthetics and certain heart medications. They should be used cautiously in patients taking antiarrhythmic drugs (like amiodarone or beta-blockers) due to the potential for additive cardiac effects.

This formulation is designed to treat a variety of disease states. Baclofen and Gabapentin can help manage neuropathic pain, while Ketoprofen provides anti-inflammatory effects. Lidocaine and Prilocaine offer local numbing to the application area, providing immediate relief from pain or discomfort. This combination can be particularly useful in conditions like fibromyalgia, diabetic neuropathy, post-herpetic neuralgia, and certain types of arthritis.

It's crucial to inform your healthcare provider of all medications you're currently taking, including over-the-counter drugs, dietary supplements, and herbal products, to avoid potential drug interactions. If you have any questions or concerns about this formulation, please don't hesitate to reach out to us at Bayview Pharmacy. We're here to help ensure your treatment is safe and effective.

How Does it Work

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This formulation is a combination of five active ingredients: Baclofen, Gabapentin, Ketoprofen, Lidocaine, and Prilocaine, each playing a unique role in managing pain and inflammation. The gel is designed to be applied topically, directly to the area of discomfort, allowing for targeted treatment.

Baclofen is a muscle relaxant and antispastic agent. It works by restoring the normal transmission of nerve signals in certain parts of the brain. In this formulation, it helps to relieve muscle spasms and tightness.

Gabapentin is an anticonvulsant and nerve pain medication. It works by affecting the chemicals and nerves in the body that are involved in the cause of seizures and some types of pain. In this formulation, it helps to reduce nerve pain.

Ketoprofen is a nonsteroidal anti-inflammatory drug (NSAID). It works by reducing hormones that cause inflammation and pain in the body. In this formulation, it helps to reduce inflammation and pain.

Lidocaine and Prilocaine are local anesthetics. They work by blocking nerve signals in your body, causing temporary numbness or loss of sensation in the area of application. In this formulation, they help to numb the skin and block pain signals.

The gel formulation allows for easy and precise application, and the pump mechanism ensures that the correct dose is dispensed each time. The gel is absorbed through the skin, directly targeting the area of discomfort and providing relief from pain and inflammation.

This formulation can be used to treat a variety of disease states that involve pain and inflammation, including but not limited to neuropathic pain, musculoskeletal pain, and certain types of chronic pain. It is important to note that this formulation should be used as directed by a healthcare provider, and patients should reach out to their healthcare provider if they have any questions or concerns.

If you have any questions about this formulation, please don't hesitate to reach out to us at Bayview Pharmacy. Our team of knowledgeable compounding pharmacists is here to help.

Other Uses

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The compound formulation of Baclofen 2%/Gabapentin 6%/Ketoprofen 6%/Lidocaine 2%/Prilocaine 2% Topical Gel is specifically designed to provide targeted relief, primarily prescribed for pain management, including neuropathic pain, mucositis, and the symptomatic relief of musculoskeletal discomfort. However, it also has potential off-label uses that may provide benefits in other health situations.

This medication's key ingredients can assist in various dermatological or localized challenges. The lidocaine and prilocaine elements have anaesthetic properties that might help manage itchiness and discomfort associated with minor burns, scrapes, cuts, and some skin conditions like psoriasis. Gabapentin, which is principally used in relieving neuralgia, may also benefit patients who suffer from restless leg syndrome. Its anti-seizure nature can make it a possible consideration for patients with epilepsy, although this should be under strict supervision of your healthcare provider.

Ketoprofen, a nonsteroidal anti-inflammatory drug (NSAID), may provide relief in cases of osteoarthritis or rheumatoid arthritis due to its potent analgesic effects. Furthermore, baclofen, which is characterized as a muscle relaxant and antispastic agent, might assist patients struggling with stiffness or spasms associated with conditions like multiple sclerosis or spinal cord injuries or diseases. It should be noted that any suggested off-label use must be approached with considerable caution and with a supervising healthcare professional's explicit approval.

Lastly, this versatile formulation is often utilized for conditions involving chronic pain or inflammation, including but not limited to diabetic peripheral neuropathy, post-herpetic neuralgia, osteoarthritis, and reflex sympathetic dystrophy. This formulation is also often used in palliative care settings to improve the quality of life for patients dealing with severe terminal conditions where pain management is a central concern.

This information intends to engage and enlighten both patients and prescribers about the potential possibilities of the Baclofen 2%/Gabapentin 6%/Ketoprofen 6%/Lidocaine 2%/Prilocaine 2% Topical Gel formulation. Our main goal is to ensure optimum use for the maximum benefit of patients, relying on the precise and extensive knowledge of treating physicians, to determine if this formulation will be effective and safe for any other purposes. Please do not hesitate to reach out if you have any inquiries or require further information.

Frequently Asked Questions

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What is a Baclofen 2%/Gabapentin 6%/Ketoprofen 6%/Lidocaine 2%/Prilocaine 2% Topical Gel?

This is a compounded medication that combines the active ingredients of Baclofen, Gabapentin, Ketoprofen, Lidocaine, and Prilocaine in a gel-like form that is applied topically onto the skin. The percentages represent the concentration of each ingredient in the formulation.

How is this compounded formulation dispensed?

This medication is dispensed through a pump mechanism, which ensures easy and precise application of the gel onto the skin.

What is the consistency of this topical gel?

The product is a semi-solid gel. This consistency helps it to stay where it is applied and allows for targeted treatment.

What is the purpose of the different ingredients in the compounded formulation?

Baclofen, Gabapentin, and Ketoprofen are used for their analgesic and anti-inflammatory effects. Lidocaine and Prilocaine are local anesthetics used to numb the applied area, providing relief from pain or discomfort.

How often should I use this medication?

You should use this medication as advised by your healthcare provider. The frequency of usage may vary depending on the condition being treated and your personal health status.

What are the side effects of this medication?

Some common side effects include skin irritation, redness, or itchiness at the application site. However, because the medication is applied topically, it generally has fewer systemic side effects than oral medications. Always report any unusual side effects to your healthcare provider.

Can this medication be used by everyone?

It's crucial to consult with your healthcare provider before starting any new medication, including this topical gel. They will consider your overall health, potential drug interactions, and the specific condition being treated before recommending this treatment.

How should I store this medication?

The medication should be stored in a cool, dry place, away from direct sunlight. Always refer to the storage instructions provided on the medication package or given by your pharmacist.

What should I do if I miss a dose?

If you miss a dose, you should apply it as soon as you remember. However, if it is close to the time of your next dose, you should skip the missed dose and go back to your regular dosing schedule. Do not double up on doses to make up for a missed one.

Can I use other topical products while using this medication?

Discuss use of other topical products with your healthcare provider, as they can potentially interfere with the absorption and effectiveness of the medication. It is generally recommended to apply this medication to clean, dry skin and allow it to fully absorb before applying any other products.

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Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.

No compounded medications are reviewed by the FDA for safety or efficacy.