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Formulas

Baclofen 2%/Gabapentin 6%/Ketoprofen 20% Topical Gel

This formulation is a compounded topical gel containing Baclofen 2%, Gabapentin 6%, and Ketoprofen 20%. It is a semisolid formulation dispensed through a pump mechanism, which allows for easy and precise application on the skin. The gel-like consistency ensures targeted treatment or absorption of the active ingredients.

The Baclofen component is a muscle relaxant and antispastic agent, Gabapentin is an anticonvulsant and nerve pain medication, and Ketoprofen is a nonsteroidal anti-inflammatory drug (NSAID). Together, these ingredients work synergistically to manage and alleviate symptoms associated with various disease states, including neuropathic pain, muscle spasms, and inflammation.

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Gabapentin
Ketoprofen
Baclofen
Topical Gel
6535ab0a1829a217ae6d3630
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Formula Information

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This formulation is a compounded topical gel containing Baclofen 2%, Gabapentin 6%, and Ketoprofen 20%. It is a semisolid formulation dispensed through a pump mechanism, which allows for easy and precise application on the skin. The gel-like consistency ensures that the active ingredients are absorbed effectively into the targeted area for optimal therapeutic effect.

Baclofen is a muscle relaxant and antispasmodic agent that works by reducing muscle tone. It is often used in the management of spasticity (muscle stiffness) associated with conditions like multiple sclerosis and spinal cord injuries. Gabapentin is an anticonvulsant and nerve pain medication that is commonly used to treat neuropathic pain conditions, including postherpetic neuralgia and diabetic neuropathy. Ketoprofen is a nonsteroidal anti-inflammatory drug (NSAID) that reduces inflammation and pain by inhibiting the production of prostaglandins, substances in the body that cause inflammation.

When combined in a topical gel, these three active ingredients can provide targeted relief for a variety of pain conditions. The gel formulation allows for direct application to the affected area, reducing systemic side effects often associated with oral medications. This makes it a suitable option for patients who may have difficulty swallowing pills or those who prefer a topical treatment method.

It's important to note that this is a compounded medication, meaning it is made specifically for the patient based on a doctor's prescription. The strength and combination of the active ingredients can be adjusted to meet the individual needs of each patient. As with any medication, it's crucial to use this product as directed by your healthcare provider to ensure its safety and effectiveness.

If you have any questions about this formulation or how it may benefit you, please don't hesitate to reach out to us. Our team of knowledgeable compounding pharmacists at Bayview Pharmacy is always here to help.

Drug Interactions

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This compounded formulation contains Baclofen, Gabapentin, and Ketoprofen, which are medications used to manage pain and inflammation. Baclofen is a muscle relaxant and antispasmodic agent, Gabapentin is an anticonvulsant and nerve pain medication, and Ketoprofen is a nonsteroidal anti-inflammatory drug (NSAID). When combined in a topical gel, these medications can provide targeted relief for conditions such as neuropathic pain, musculoskeletal pain, and inflammation.

It's important to be aware of potential drug interactions when using this formulation. Baclofen may interact with other central nervous system depressants, including alcohol, benzodiazepines, opioids, and antihistamines, potentially leading to increased sedation or respiratory depression. Gabapentin may interact with antacids containing magnesium or aluminum, potentially reducing the absorption of Gabapentin. Ketoprofen may interact with blood thinners, other NSAIDs, and certain high blood pressure medications, potentially increasing the risk of bleeding or kidney problems.

Patients should inform their healthcare provider of all medications they are currently taking, including prescription drugs, over-the-counter medications, vitamins, and herbal supplements. This will help the healthcare provider to manage potential drug interactions and ensure the safe use of this compounded formulation.

While this formulation is designed for topical use and is less likely to interact with systemic medications compared to oral drugs, some absorption into the bloodstream can still occur. Therefore, patients should still be monitored for potential drug interactions, especially if they have kidney or liver disease, as these conditions may affect the body's ability to metabolize and eliminate these medications.

Patients should also be aware that this formulation should not be applied to broken or irritated skin, as this may increase absorption into the bloodstream and the potential for systemic side effects. If irritation or an allergic reaction occurs, such as redness, itching, or swelling at the application site, patients should discontinue use and contact their healthcare provider.

If you have any questions about this formulation or its potential interactions with other medications, please don't hesitate to reach out to us. We are here to help ensure that you can use this medication safely and effectively.

How Does it Work

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This formulation combines three active ingredients: Baclofen, Gabapentin, and Ketoprofen, each with a unique mechanism of action to provide relief from various disease states. The formulation is designed to be applied topically, directly to the skin, where it can be absorbed and exert its therapeutic effects.

Baclofen is a muscle relaxant and antispastic agent. It works by inhibiting the transmission of reflexes at the spinal level, which can help to reduce muscle spasms, pain, and stiffness. This makes it particularly useful in conditions such as multiple sclerosis and spinal cord injuries.

Gabapentin is an anticonvulsant and nerve pain medication. It is believed to work by affecting the way nerves send messages to your brain, reducing the perception of pain. It is commonly used to treat nerve pain conditions such as postherpetic neuralgia and diabetic neuropathy.

Ketoprofen is a nonsteroidal anti-inflammatory drug (NSAID). It works by reducing hormones that cause inflammation and pain in the body. It is commonly used to relieve pain, swelling, and joint stiffness caused by arthritis, gout, sprains, and other injuries.

The combination of these three medications in a topical gel allows for targeted treatment. The gel is applied directly to the area of pain or discomfort, allowing the active ingredients to be absorbed through the skin and act directly on the affected area. This can provide more effective relief with fewer systemic side effects than oral medications.

As a semisolid formulation dispensed through a pump mechanism, this product is easy to apply and allows for precise dosing. The gel-like consistency helps to ensure that the medication stays in contact with the skin for optimal absorption.

It's important to use this medication as directed by your healthcare provider. Always apply the gel to clean, dry skin and wash your hands thoroughly after application. Avoid contact with the eyes, mouth, and other mucous membranes.

If you have any questions about this formulation or how to use it, please don't hesitate to reach out to us at Bayview Pharmacy. Our team of knowledgeable compounding pharmacists is here to help.

Other Uses

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This compound formulation of Baclofen, Gabapentin and Ketoprofen in gel form, along with its key role in managing neuropathic pain conditions, may also show potential benefits in other ailments. It is important for patients and prescribers to understand that, while not approved for all of these uses, some may find the gel beneficial for other conditions as advised by a healthcare provider.

Beyond its traditional use, this medication can serve as an option for patients who are battling other forms of persistent and debilitating pain, both acute and chronic, including arthritis, musculoskeletal pain, and fibromyalgia. The non-systemic absorption provided by the topical application can decrease potential systemic side effects seen with oral medications. Each active ingredient in this topical gel has a unique mechanism of action that provides pain relief: Baclofen for muscle relaxation, Gabapentin for neuropathic pain, and Ketoprofen as an anti-inflammatory and analgesic agent.

Additionally, some clinical research suggests that Baclofen has potential implications in conditions such as hiccups, alcohol withdrawal, and gastroesophageal reflux disease, although these are off-label uses. Gabapentin, too, has been reported to help with restless leg syndrome, insomnia, and some anxiety disorders. Ketoprofen can be useful in managing acute migraines, although this application is also outside the FDA-approved range for the medication.

It is important to note that while this formulation may be used for conditions other than its primary indication, it should only be used under the guidance and supervision of an experienced healthcare professional. Individuals should discuss these potential uses with their prescriber or pharmacist to determine the most safe and effective course of action.

For those considering this gel formulation for uses outside of pain management, whether you're a patient or healthcare professional, please reach out to us at Bayview Pharmacy for further information. Our team of expert compounding pharmacists are here to guide and support you every step of the way, ensuring your medication needs are met in the most efficient, safe, and beneficial manner.

Frequently Asked Questions

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What is the Baclofen 2%/Gabapentin 6%/Ketoprofen 20% Topical Gel?

This is a compounded formulation of medicines, consisting of Baclofen, Gabapentin, and Ketoprofen. This semisolid formulation is dispensed through a pump mechanism and is designed for direct application on the skin for targeted treatment.

How does the topical gel work?

This medication delivers active ingredients directly to a specific area of the body. It absorbs into the skin and works by reducing inflammation, nerve pain, and muscle stiffness.

How do you apply the Baclofen/Gabapentin/Ketoprofen topical gel?

You can apply the gel by dispensing the correct dose via the pump mechanism straight onto the affected area. Always wash your hands before and after application, and do not apply to open or wounded skin.

What is the consistency of this medication?

This medicine is a semisolid formulation with a gel-like consistency designed to allow for easy and precise application onto the skin.

Can this gel be used for all types of pain?

Not necessarily. This gel is specifically formulated for the treatment of conditions that benefit from the combined use of Baclofen, Gabapentin, and Ketoprofen, such as neuropathic pain or muscular pain. Always consult with a healthcare provider for suitable treatment options for specific conditions.

How long does it take for this medication to work?

The absorption rates and effectiveness can vary from person to person, depending on multiple factors such as the severity of the condition or the individual's metabolism. Always consult your healthcare provider for more accurate information.

Can you use this gel with other medications?

This depends on the specific medications in question. Some may interact with the active ingredients in the gel, potentially altering its effectiveness or causing side effects. Always consult with a healthcare provider before combining treatments.

Who should not use this medication?

People with allergies to any of the active ingredients (Baclofen, Gabapentin, Ketoprofen), those with specific medical conditions, or those who are pregnant or breastfeeding may not be advised to use this medication. Please consult with a doctor if unsure.

Does this medication have any side effects?

Like all medications, this gel may have potential side effects, including skin reactions at the site of application. However, side effects are not guaranteed and vary from person to person. Always consult with your healthcare provider for information tailored to your specific circumstances.

Does this topical gel require a prescription?

Yes. This particular combination of Baclofen, Gabapentin, and Ketoprofen is a prescription medication. Always obtain it from a reputable pharmaceutical source with a valid prescription.

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Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.

No compounded medications are reviewed by the FDA for safety or efficacy.