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Baclofen 2%/Cyclobenzaprine HCl 2%/Gabapentin 6%/Ketoprofen 10%/Lidocaine HCl 2% Topical Gel

This formulation is a semisolid topical gel containing Baclofen 2%, Cyclobenzaprine HCl 2%, Gabapentin 6%, Ketoprofen 10%, and Lidocaine HCl 2%. It is dispensed through a pump mechanism, which allows for easy and precise application on the skin. The gel-like consistency ensures targeted treatment or absorption of the active ingredients.

The combination of these active ingredients is designed to treat a variety of disease states. Baclofen is a muscle relaxant and antispastic agent, Cyclobenzaprine HCl is a muscle relaxant, Gabapentin is used to manage neuropathic pain, Ketoprofen is a nonsteroidal anti-inflammatory drug (NSAID) for pain relief, and Lidocaine HCl is a local anesthetic. Together, they provide comprehensive treatment for conditions such as muscle spasms, neuropathic pain, inflammation, and localized pain.

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Topical Gel
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Formula Information

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This formulation is a compounded topical gel containing Baclofen 2%, Cyclobenzaprine HCl 2%, Gabapentin 6%, Ketoprofen 10%, and Lidocaine HCl 2%. It is a semisolid formulation that is dispensed through a pump mechanism, allowing for easy and precise application on the skin. The gel-like consistency ensures that the active ingredients are absorbed directly into the targeted area, providing localized relief.

Baclofen is a muscle relaxant and antispastic agent that helps to relieve muscle spasms, tightness, and pain. Cyclobenzaprine HCl is another muscle relaxant that works by blocking nerve impulses (or pain sensations) that are sent to your brain. Gabapentin is an anticonvulsant and nerve pain medication that is often used to treat nerve pain and discomfort. Ketoprofen is a nonsteroidal anti-inflammatory drug (NSAID) that reduces hormones that cause inflammation and pain in the body. Lastly, Lidocaine HCl is a local anesthetic that works by causing temporary numbness/loss of feeling in the skin and mucous membranes.

This formulation is often used to treat a variety of disease states that involve pain and inflammation, such as neuropathic pain, fibromyalgia, musculoskeletal pain, and certain types of arthritis. By combining these active ingredients into one topical gel, it allows for targeted treatment and potentially reduces the need for systemic medication, which can often have more side effects.

It's important to note that this is a compounded medication, meaning it is made specifically for you based on a doctor's prescription. It is not a commercially available product and should be used under the guidance of a healthcare professional. As with any medication, it's important to use this product as directed by your healthcare provider and report any side effects or adverse reactions immediately.

If you have any questions about this formulation, its uses, or how it may benefit you, please don't hesitate to reach out to us at Bayview Pharmacy. Our knowledgeable team of compounding pharmacists is here to help.

Drug Interactions

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This topical gel formulation contains a combination of Baclofen, Cyclobenzaprine HCl, Gabapentin, Ketoprofen, and Lidocaine HCl. These active ingredients work synergistically to manage pain and inflammation associated with various conditions such as neuropathic pain, muscle spasms, and arthritis. However, it's important to be aware of potential drug interactions that may occur with this formulation.

Baclofen, a muscle relaxant, may interact with other central nervous system depressants like alcohol, benzodiazepines, opioids, and antihistamines, potentially leading to increased sedation and respiratory depression. Cyclobenzaprine HCl, another muscle relaxant, has similar interactions. It's also important to note that using Cyclobenzaprine with monoamine oxidase inhibitors (MAOIs) or within 14 days of stopping an MAOI may lead to serious, life-threatening side effects.

Gabapentin, an anticonvulsant and nerve pain medication, may interact with antacids containing magnesium or aluminum, as they can reduce the amount of Gabapentin that the body absorbs, making it less effective. It's recommended to take Gabapentin at least 2 hours after taking an antacid.

Ketoprofen, a nonsteroidal anti-inflammatory drug (NSAID), may interact with blood thinners, corticosteroids, other NSAIDs, and certain high blood pressure medications, potentially increasing the risk of gastrointestinal bleeding. It may also interact with lithium and methotrexate, increasing the levels of these drugs in the body.

Lidocaine HCl, a local anesthetic, has few systemic interactions due to its local application. However, it may interact with other local anesthetics and antiarrhythmic drugs such as beta-blockers and calcium channel blockers.

It's crucial to inform your healthcare provider about all the medications, supplements, and herbal products you are currently taking to avoid potential drug interactions. This includes over-the-counter medications and products not typically considered medication, such as alcohol and cannabis. It's also important to follow the prescribed dosage and application instructions to ensure the safe and effective use of this medication.

If you have any questions or concerns about this formulation or its potential interactions, please don't hesitate to reach out to us. We are here to provide you with the information and support you need to manage your health effectively.

How Does it Work

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This formulation is a combination of five active ingredients: Baclofen, Cyclobenzaprine HCl, Gabapentin, Ketoprofen, and Lidocaine HCl. Each of these ingredients plays a unique role in managing pain and inflammation, and their combined effect can provide significant relief for a variety of disease states.

Baclofen is a muscle relaxant and antispastic agent. It works by inhibiting the transmission of reflexes at the spinal level, which can help to reduce muscle spasms, pain, and stiffness.

Cyclobenzaprine HCl is another muscle relaxant that works by blocking nerve impulses (or pain sensations) that are sent to your brain. It is particularly effective in treating muscle spasms.

Gabapentin is an anticonvulsant and nerve pain medication. It works by affecting the chemicals and nerves in the body that are involved in the cause of seizures and some types of pain. It is particularly effective in treating nerve pain.

Ketoprofen is a nonsteroidal anti-inflammatory drug (NSAID). It works by reducing hormones that cause inflammation and pain in the body. It is particularly effective in treating pain or inflammation caused by arthritis.

Lidocaine HCl is a local anesthetic. It works by blocking nerve signals in your body, which can help to numb the area and reduce pain or discomfort.

The formulation is designed to be applied topically, which means it is applied directly to the skin in the area where relief is needed. The gel-like consistency allows for easy and precise application, and the pump mechanism ensures that the correct dose is dispensed each time. The active ingredients are then absorbed through the skin, providing targeted treatment to the affected area.

This formulation can be used to treat a variety of disease states, including muscle spasms, nerve pain, and inflammation caused by arthritis. It can also be used to manage pain and discomfort associated with other conditions, as directed by a healthcare provider.

If you have any questions about this formulation, or if you would like more information about how it works, please don't hesitate to reach out to us at Bayview Pharmacy. Our team of knowledgeable compounding pharmacists is always here to help.

Other Uses

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This formulation, Baclofen 2%/Cyclobenzaprine HCl 2%/Gabapentin 6%/Ketoprofen 10%/Lidocaine HCl 2% Topical Gel, while typically prescribed for the management of neuropathic pain, muscular discomfort, and inflammation, has potential for application in a variety of other clinical scenarios due to its wide spectrum of active ingredients that have individual and synergistic effects.

Given the presence of Baclofen, a muscle relaxant, and Cyclobenzaprine HCl, another muscle relaxant and nerve pain medication, this topical gel may be used to relieve pain resulting from spasmodic torticollis, a condition characterized by involuntary contraction of the neck muscles. These ingredients also make it suitable for managing the discomfort associated with fibromyalgia and other muscle spasms.

The presence of Gabapentin and Lidocaine HCl supports its use for the treatment of post-herpetic neuralgia, a complication of shingles that continues even after the blisters have cleared up. The anti-inflammatory action of Ketoprofen could potentially benefit those suffering from conditions such as osteoarthritis or rheumatoid arthritis, while the local anesthesia provided by Lidocaine HCl further enhances pain relief.

Off-label, the combination of these agents has been considered for managing pain associated with diabetic neuropathy, given the ingredients' effects on nerve-associated pain. Additionally, its local application makes it a potential remedy for localized peripheral neuropathic conditions, such as carpal tunnel syndrome.

While these are potentially applicable scenarios, it's important that individuals should not use the product for these conditions without first consulting with a healthcare provider. As experienced compounding pharmacists, we can't underscore enough the importance of using medication as directed by a healthcare provider. If there's need for further clarification or inquiries about this formulation, please don't hesitate to reach out to us at Bayview Pharmacy.

Frequently Asked Questions

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What is Baclofen 2%/Cyclobenzaprine HCl 2%/Gabapentin 6%/Ketoprofen 10%/Lidocaine HCl 2% Topical Gel?

This is a compounded medication that contains five active ingredients: Baclofen, Cyclobenzaprine HCl, Gabapentin, Ketoprofen, and Lidocaine HCl. It is a semisolid formulation delivered through a pump for targeted application on the skin.

How should I apply this compounded medication?

Use the pump to dispense the medication and apply it directly to the target area of the skin as directed by your healthcare provider. Rub it in gently until it is completely absorbed.

What are the active ingredients in this topical gel?

The active ingredients are Baclofen, Cyclobenzaprine HCl, Gabapentin, Ketoprofen, and Lidocaine HCl. These drugs work together to alleviate pain and inflammation.

What is the consistency of this medication?

The medication is a semisolid gel. It's designed to be easily and precisely applied to the skin through a pump mechanism.

What is the purpose of the pump mechanism?

The pump mechanism is designed for easy and precise application. It ensures you apply the right amount exactly where you need it.

Can I use this medication for any kind of pain?

This medication is typically prescribed for specific types of pain such as neuropathic pain. Always follow your healthcare provider's instructions on how to use this medication.

What are the side effects of this medication?

Side effects may include skin irritation or rash at the site of application. If you notice any severe side effects, such as difficulty breathing, swelling, or intense itchiness, contact your healthcare provider immediately.

How often should I apply this compounded medication?

The frequency and dose of use should be as directed by your healthcare provider. Ensure to follow the instructions on your prescription label carefully.

Is this topical gel safe for all skin types?

Generally, it should be safe for most skin types, but if you have very sensitive skin or any specific skin conditions, discuss this with your healthcare provider before use.

What should I do if I forget to apply my medication?

If you miss a dose, apply it as soon as you remember. If it is close to the time for your next dose, skip the missed dose and go back to your normal time. Do not apply twice or extra doses unless directed by your healthcare provider.

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Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.

No compounded medications are reviewed by the FDA for safety or efficacy.