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Baclofen 2%/Cyclobenzaprine HCl 2%/Gabapentin 4%/Ketamine HCl 11 5%/Ketoprofen 10% Topical Gel

This formulation is a semisolid topical gel containing Baclofen 2%, Cyclobenzaprine HCl 2%, Gabapentin 4%, Ketamine HCl 11.5%, and Ketoprofen 10%. It is dispensed through a pump mechanism, which allows for easy and precise application on the skin. The active ingredients in this gel are designed to provide targeted treatment and absorption for various disease states.

The combination of these active ingredients is commonly used to manage and treat conditions such as neuropathic pain, muscle spasms, and inflammation. Baclofen and Cyclobenzaprine HCl are muscle relaxants that help to reduce muscle spasms. Gabapentin is used to treat nerve pain. Ketamine HCl is a potent analgesic that provides relief from severe pain, and Ketoprofen is a nonsteroidal anti-inflammatory drug (NSAID) that reduces pain and inflammation.

This formulation is designed to deliver the medication directly to the affected area, providing targeted relief while minimizing systemic side effects. It is an ideal option for patients who require consistent and localized treatment for their disease states.

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Topical Gel
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Formula Information

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This formulation is a compounded topical gel containing Baclofen 2%, Cyclobenzaprine HCl 2%, Gabapentin 4%, Ketamine HCl 11.5%, and Ketoprofen 10%. It is a semisolid formulation dispensed through a pump mechanism, which allows for easy and precise application on the skin. The gel-like consistency ensures targeted treatment or absorption of the active ingredients.

Baclofen is a muscle relaxant and antispastic agent. It works by reducing the frequency and severity of muscle spasms caused by neurological disorders. Cyclobenzaprine HCl is another muscle relaxant that works by blocking nerve impulses (or pain sensations) that are sent to your brain. Gabapentin is an anticonvulsant and nerve pain medication that is often used to treat nerve pain and seizures. It works by affecting the chemicals and nerves in the body that are involved in the cause of seizures and some types of pain.

Ketamine HCl is a powerful anesthetic that provides pain relief by blocking certain receptors in the brain. It is often used in the management of chronic pain conditions, including neuropathic pain and complex regional pain syndrome (CRPS). Ketoprofen is a nonsteroidal anti-inflammatory drug (NSAID) that works by reducing hormones that cause inflammation and pain in the body. It is commonly used to relieve pain, swelling, and joint stiffness caused by arthritis.

This combination of active ingredients in a topical gel formulation allows for targeted treatment of various disease states. It can be used to manage conditions such as muscle spasms, nerve pain, chronic pain conditions, and inflammatory conditions. The topical application allows for direct delivery of the medication to the affected area, reducing systemic side effects often associated with oral medications.

As with any medication, it is important to use this formulation as directed by your healthcare provider. Side effects may include skin irritation at the application site. If you experience any unusual symptoms, contact your healthcare provider immediately. Always inform your healthcare provider of any other medications you are taking to avoid potential drug interactions.

If you have any questions about this formulation, please do not hesitate to reach out to us at Bayview Pharmacy. Our team of knowledgeable compounding pharmacists is here to assist you.

Drug Interactions

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This topical gel formulation contains a combination of Baclofen, Cyclobenzaprine HCl, Gabapentin, Ketamine HCl, and Ketoprofen. These active ingredients work synergistically to provide pain relief, muscle relaxation, and anti-inflammatory effects, making it an effective treatment for conditions such as neuropathic pain, muscle spasms, and inflammation associated with various disease states.

However, it's important to be aware of potential drug interactions. Baclofen, a muscle relaxant, may interact with other central nervous system depressants like alcohol, benzodiazepines, opioids, and antihistamines, potentially leading to increased sedation or respiratory depression. Similarly, Cyclobenzaprine HCl, another muscle relaxant, can interact with monoamine oxidase inhibitors (MAOIs), causing serious side effects such as high fever, convulsions, and even death.

Gabapentin, an anticonvulsant and nerve pain medication, may interact with antacids containing magnesium or aluminum, potentially reducing the absorption of Gabapentin. It's recommended to take Gabapentin at least 2 hours after taking an antacid. Ketamine HCl, an anesthetic, can interact with other anesthetics or sedatives, potentially leading to increased sedation or respiratory depression.

Ketoprofen, a nonsteroidal anti-inflammatory drug (NSAID), may interact with anticoagulants, antiplatelet drugs, and other NSAIDs, potentially increasing the risk of bleeding. It may also interact with angiotensin-converting enzyme (ACE) inhibitors, angiotensin II receptor blockers (ARBs), or diuretics, potentially reducing their effectiveness or increasing the risk of kidney damage.

It's important to inform your healthcare provider of all medications, supplements, and over-the-counter products you are currently taking to avoid potential drug interactions. This includes any creams, ointments, or other topical products, as these can also interact with the active ingredients in this formulation.

While this formulation is designed for topical use and is generally considered to have a lower risk of systemic side effects compared to oral medications, it's still possible for the active ingredients to be absorbed into the bloodstream, especially if used over large areas of skin or for prolonged periods. Therefore, it's important to use this product as directed by your healthcare provider and to report any unusual side effects or symptoms.

If you have any questions or concerns about this formulation or its potential interactions, please don't hesitate to reach out to us. Our team of knowledgeable compounding pharmacists at Bayview Pharmacy is always here to help.

How Does it Work

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This formulation is a combination of five active ingredients: Baclofen, Cyclobenzaprine HCl, Gabapentin, Ketamine HCl, and Ketoprofen. Each of these ingredients plays a unique role in managing pain and inflammation, and their combined effect can provide significant relief for a variety of disease states.

Baclofen is a muscle relaxant and antispastic agent. It works by inhibiting the transmission of reflexes at the spinal level, which can help to reduce muscle spasms, pain, and stiffness.

Cyclobenzaprine HCl is another muscle relaxant. It acts centrally within the brain stem and reduces muscle hyperactivity, which can help to relieve muscle spasms and associated pain.

Gabapentin is an anticonvulsant and nerve pain medication. It works by stabilizing electrical activity in the nervous system and reducing the release of neurotransmitters that signal pain. This can help to relieve nerve pain and discomfort.

Ketamine HCl is a powerful anesthetic. It works by blocking the NMDA receptor, which plays a key role in pain signaling. This can help to provide significant pain relief, particularly for chronic and neuropathic pain conditions.

Ketoprofen is a nonsteroidal anti-inflammatory drug (NSAID). It works by reducing the production of prostaglandins, which are chemicals that cause inflammation, pain, and fever in the body. This can help to reduce inflammation and associated pain.

The formulation is designed to be applied topically, which means it is applied directly to the skin over the area of pain or inflammation. The active ingredients are then absorbed through the skin and directly into the affected area. This allows for targeted treatment and can reduce the risk of systemic side effects compared to oral medications.

This formulation can be used to treat a variety of disease states, including but not limited to: muscle spasms, nerve pain, chronic pain conditions, and inflammatory conditions. As always, it is important to use this medication as directed by a healthcare provider, and to discuss any questions or concerns with a pharmacist or other healthcare professional.

If you have any questions about this formulation, or if you would like more information about how it works, please don't hesitate to reach out to us at Bayview Pharmacy. Our team of knowledgeable compounding pharmacists is always here to help.

Other Uses

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This complex formulation incorporates a variety of active ingredients, each with a unique therapeutic role. Predominantly, this formulation is applied topically for managing and treating different types of pain including neuropathic pain (nerve pain), muscle relaxations, and musculoskeletal pain. However, there could be certain other uses for this formulation, beyond those specifically related to pain management.

Baclofen and cyclobenzaprine present in the formulation are typically used to encourage muscle relaxation. Therefore, the formulation can also be employed in managing conditions that involve muscle spasms or tension, such as spasticity resulting from conditions like cerebral palsy, multiple sclerosis, or spinal cord injury.

Additionally, the presence of gabapentin could diversify the application of this compound to conditions where an evidence-based symptom relief for nerve pain is needed. It gains advantage in the management of postherpetic neuralgia (pain following shingles) or pain associated with diabetic peripheral neuropathy.

Ketamine HCl stands strong for its analgesic properties in managing chronic pain especially for patients who have developed tolerance or are refractory to other analgesics. It can also be found proving significant relief in complex regional pain syndrome and in managing pain in opioid-tolerant patients.

Finally, ketoprofen, a non-steroidal anti-inflammatory drug (NSAID), is frequently prescribed to reduce inflammation and to alleviate pain in conditions like rheumatoid arthritis and osteoarthritis. Its presence might be beneficial in aiding symptoms of such inflammatory conditions while providing its potent analgesic effect.

In conclusion, this formulation could potentially be utilized in a broader range of conditions relating to pain, spasticity, inflammation and neuropathy. However, it's essential to remember that the safety, dosage, efficacy, interaction of this formulation might vary among individuals and hence, professional medical advice is always recommended. If you have any questions or concerns about this formulation or its possible uses, please don't hesitate to reach out to us at Bayview Pharmacy. We are always here to help.

Frequently Asked Questions

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What is this compounded formulation all about?

This formulation is a blend of Baclofen, Cyclobenzaprine HCl, Gabapentin, Ketamine, HCl and Ketoprofen. These active ingredients are mixed together in a semisolid gel to facilitate easy and precise application on the skin, intended for targeted treatment or absorption.

How do I use this product?

This product comes with a pump mechanism that allows for precise dispensing of the medication. The gel is to be applied directly on the skin over the area that requires treatment.

What conditions does this medication treat?

As a compounded medication, this formulation may be used to treat a wide range of conditions, including but not limited to muscle pain, nerve pain, inflammation and other disorders as prescribed by your healthcare provider.

Is this formulation safe to use?

Yes, this formulation is generally safe to use. However, as with any medication, please use this product as directed by your healthcare provider and discuss any potential risks or concerns with them.

Can I experience any side effects?

As with any medication, this product may carry the risk of side effects. If you experience any unusual or severe reactions, please immediately consult your healthcare provider.

Can I use this product on any part of my body?

This product is intended for topical application only. Apply it on the skin over the area requiring treatment. Avoid areas like the eyes or open wounds. If you have any doubt, please consult your healthcare provider.

Can I use other medications while using this product?

Before using this medication alongside others, please discuss it with your healthcare provider to avoid any potential drug interactions.

How should I store the medication?

Store the medication in a cool, dry place away from sunlight. Always keep the pump bottle tightly closed when not in use.

Can I use the product if I'm pregnant or breastfeeding?

If you are pregnant or breastfeeding, you should discuss the use of this formulated product with your healthcare provider to ensure safety.

What should I do if I miss a dose?

If you miss a dose, apply it as soon as you remember. However, if it's close to the time for the next dose, wait until that time. Do not try to catch up by applying more of the medication.

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Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.

No compounded medications are reviewed by the FDA for safety or efficacy.