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Baclofen 2%/Cyclobenzaprine HCl 2%/Diclofenac Sodium 3%/Ketoprofen 10%/Lidocaine HCl 3% Topical Gel

This formulation is a semisolid topical gel containing Baclofen 2%, Cyclobenzaprine HCl 2%, Diclofenac Sodium 3%, Ketoprofen 10%, and Lidocaine HCl 3%. It is dispensed through a pump mechanism, which allows for easy and precise application on the skin. The active ingredients in this formulation are designed to provide targeted treatment and absorption through the skin.

The combination of these active ingredients is intended to treat a variety of disease states. Baclofen and Cyclobenzaprine HCl are muscle relaxants used to relieve muscle spasms and pain. Diclofenac Sodium and Ketoprofen are nonsteroidal anti-inflammatory drugs (NSAIDs) that reduce pain, swelling, and inflammation. Lidocaine HCl is a local anesthetic that provides temporary relief from pain and discomfort.

This formulation is particularly beneficial for patients suffering from conditions such as arthritis, muscle sprains and strains, back pain, nerve pain, and other related conditions. The gel-like consistency allows for targeted application, ensuring that the medication is delivered directly to the affected area.

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Topical Gel
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Formula Information

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This formulation is a compounded topical gel containing Baclofen 2%, Cyclobenzaprine HCl 2%, Diclofenac Sodium 3%, Ketoprofen 10%, and Lidocaine HCl 3%. It is a semisolid formulation that is dispensed through a pump mechanism, allowing for easy and precise application on the skin. The gel-like consistency ensures that the active ingredients are absorbed directly into the targeted area, providing localized relief.

Baclofen is a muscle relaxant and antispasmodic agent that helps to relieve muscle spasms, tightness, and pain. Cyclobenzaprine HCl is another muscle relaxant that works by blocking nerve impulses (or pain sensations) that are sent to your brain. Diclofenac Sodium and Ketoprofen are nonsteroidal anti-inflammatory drugs (NSAIDs) that reduce substances in the body that cause pain and inflammation. Lidocaine HCl is a local anesthetic that works by causing temporary numbness/loss of feeling in the skin and mucous membranes. This combination of ingredients provides a multi-modal approach to pain management, addressing both the symptoms and the underlying causes of pain.

This formulation is particularly useful in treating various disease states that involve pain and inflammation. These include conditions like arthritis, muscle sprains and strains, back pain, nerve pain, and other similar conditions. By applying the gel directly to the affected area, patients can experience targeted relief without the systemic side effects often associated with oral medications.

It's important to use this medication as directed by your healthcare provider. The amount of gel to be applied and the frequency of application will depend on the condition being treated and the individual patient's response to therapy. Always wash your hands after applying the gel unless your hands are the area being treated. Avoid contact with eyes, nose, mouth, and other sensitive areas.

As with any medication, this formulation may cause side effects. These can include skin irritation at the application site, such as redness, itching, or rash. If these side effects persist or worsen, contact your healthcare provider immediately. Serious side effects are rare, but if you experience symptoms such as severe dizziness, fainting, slow or irregular heartbeat, or mental/mood changes, seek medical attention right away.

Remember, we are here to help. If you have any questions about this formulation, how to use it, or what to expect, don't hesitate to reach out to us at Bayview Pharmacy. Our knowledgeable team of compounding pharmacists is always ready to assist you.

Drug Interactions

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This topical gel formulation contains a combination of Baclofen, Cyclobenzaprine HCl, Diclofenac Sodium, Ketoprofen, and Lidocaine HCl. These active ingredients work synergistically to provide relief from pain and inflammation associated with various conditions such as muscle spasms, arthritis, and neuropathic pain. However, it's important to be aware of potential drug interactions.

Baclofen, a muscle relaxant, may interact with other central nervous system depressants like alcohol, benzodiazepines, opioids, and antihistamines, potentially leading to increased sedation and respiratory depression. Cyclobenzaprine HCl, another muscle relaxant, has similar interactions. It's also important to note that using Cyclobenzaprine with monoamine oxidase inhibitors (MAOIs) or within 14 days of stopping an MAOI may lead to serious, life-threatening side effects.

Diclofenac Sodium and Ketoprofen, both nonsteroidal anti-inflammatory drugs (NSAIDs), may interact with anticoagulants, antiplatelet drugs, and other NSAIDs, increasing the risk of gastrointestinal bleeding. They may also interact with angiotensin-converting enzyme (ACE) inhibitors, angiotensin II receptor blockers (ARBs), or diuretics, potentially reducing their effectiveness and increasing the risk of kidney damage. Furthermore, using these NSAIDs with selective serotonin reuptake inhibitors (SSRIs) or serotonin and norepinephrine reuptake inhibitors (SNRIs) may increase the risk of bleeding.

Lidocaine HCl, a local anesthetic, may interact with other local anesthetics or medications with similar metabolic pathways, potentially leading to increased systemic absorption and toxicity. It's also important to note that using Lidocaine with antiarrhythmic drugs may lead to additive cardiac effects.

It's crucial to inform your healthcare provider about all the medications you're currently taking, including prescription drugs, over-the-counter medications, vitamins, and herbal supplements, to avoid potential drug interactions. Also, avoid consuming alcohol while using this formulation as it may increase the risk of sedation and other side effects.

This formulation is intended for topical use only and should not be ingested or applied to open wounds or damaged skin. Always use this medication as directed by your healthcare provider. If you experience any unusual symptoms or side effects, contact your healthcare provider immediately.

If you have any questions or concerns about this formulation or its potential interactions, please don't hesitate to reach out to us. We're here to help.

How Does it Work

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This topical gel formulation combines five active ingredients: Baclofen, Cyclobenzaprine HCl, Diclofenac Sodium, Ketoprofen, and Lidocaine HCl. Each of these ingredients plays a unique role in managing pain and inflammation, making this formulation a comprehensive solution for a variety of disease states.

Baclofen is a muscle relaxant and antispasmodic agent. It works by inhibiting the transmission of reflexes at the spinal level, which can help to alleviate muscle spasms, pain, and stiffness. Cyclobenzaprine HCl is another muscle relaxant that works centrally within the brain stem to reduce muscle tone, thereby relieving muscle spasms and associated pain.

Diclofenac Sodium and Ketoprofen are both non-steroidal anti-inflammatory drugs (NSAIDs). They work by inhibiting the production of prostaglandins, substances in the body that cause inflammation and pain. By reducing the levels of these substances, these NSAIDs can help to alleviate pain and reduce inflammation.

Lidocaine HCl is a local anesthetic. It works by blocking nerve signals in the body, which can help to numb the area and provide temporary relief from pain and discomfort.

When applied topically, this formulation allows for targeted treatment. The active ingredients are absorbed through the skin directly into the affected area, providing localized relief without the systemic side effects often associated with oral medications. The gel-like consistency and pump mechanism allow for easy and precise application.

This formulation can be used to treat a variety of disease states that involve pain and inflammation, including but not limited to: musculoskeletal conditions such as arthritis and tendonitis, neuropathic pain conditions, and certain types of chronic pain. It may also be used to manage pain and muscle spasms associated with conditions like multiple sclerosis and spinal cord injury.

As with any medication, it's important to use this formulation as directed by a healthcare provider. Side effects can occur, including skin irritation at the application site. If you experience any unusual symptoms, contact your healthcare provider immediately.

If you have any questions about this formulation, don't hesitate to reach out to us at Bayview Pharmacy. Our team of knowledgeable compounding pharmacists is here to help.

Other Uses

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Apart from the primary indication for this combination gel, which includes conditions like muscle and joint pain, muscle spasms, and inflammation, this combination may be beneficial in the management of some other conditions.

For example, use of this formula might offer some relief in conditions where nerve pain or neurogenic inflammation are the primary drivers of discomfort. This includes conditions such as peripheral neuropathy, including diabetic neuropathy, or post-herpetic neuralgia related to shingles infection. The baclofen and lidocaine in the gel can target the neuropathic pain, while the anti-inflammatory and muscle relaxant properties of the other ingredients can indirectly reduce discomfort.

This gel formulation may also be considered for off-label use in conditions such as plantar fasciitis, where inflammation and pain are localized at the site of the heel, or carpal tunnel syndrome, where the application of a compounded formula may enhance topical absorption and decrease systematic side effects.

Additionally, the formulation might be helpful in the treatment of certain forms of dermatitis or localized inflammatory skin reactions. The diclofenac and ketoprofen in the formula have anti-inflammatory properties and might help to soothe and help these conditions.

However, it's vital to remember this compounded medication might not be fit for every patient or every condition. It's always necessary to have an informed discussion with a healthcare provider before starting a new treatment. Make sure to report any allergies, particularly to a group of drugs called NSAIDs (Non-Steroidal Anti-Inflammatory Drugs) or to local anesthetics such as lidocaine.

Please feel free to reach out to us if you have any other questions regarding this product or need extra information. We're always here to help and offer any clarifications required.

Frequently Asked Questions

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What is the purpose of this combined formulation of multiple medications?

This combination therapy serves to offer patients relief from various chronic pain conditions. Each active ingredient has a specific role, producing a synergistic effect that enhances efficacy and potentially minimizes systemic side effects.

How do I apply this topical gel?

You apply this gel directly to your skin over the painful area. It's dispensed through a pump mechanism which makes it easy and precise to apply the dosage needed.

How often should I use this medication?

This varies greatly between individual patients and the nature of their condition. It is recommended to strictly follow the guideline provided by your healthcare provider.

Can I use this medication with other prescriptions or over-the-counter drugs?

Always check with your healthcare provider before starting any new medications, including over-the-counter medications, as there may be potential interactions.

What are the potential side effects of this medication?

Common side effects may include temporary skin irritation, redness, or discomfort at the application site. Please report any persistent or worrisome side effects to your healthcare provider immediately.

What is the role of each active ingredient in this compounded formulation?

Baclofen and Cyclobenzaprine are muscle relaxants, Diclofenac and Ketoprofen are anti-inflammatories, and Lidocaine is a local anesthetic. Combined, these ingredients help alleviate pain and inflammation, relax muscles, and numb the affected area.

Can I use this medication if I am pregnant or breastfeeding?

Please consult with your healthcare provider as the effect of these active ingredients on unborn babies and nursing infants is unknown. Always discuss potential risks and benefits with your doctor.

Can children use this medication?

As with any medication, it's important to consult with a pediatrician before using this compounded formulation in children.

What should I do if I miss a dose?

If you miss a dose, apply it as soon as you remember. However, if it is near the time for the next dose, skip the missed dose and go back to your regular dosing schedule. Do not double up.

Do I need a prescription to get this medication?

Yes, this is a prescription-only medication. Usage should be under a healthcare provider's instruction and supervision.

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Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.

No compounded medications are reviewed by the FDA for safety or efficacy.