This formulation is a compounded topical gel containing Amitriptyline 20%, Ketamine 10%, Lidocaine 10%, and Prilocaine 10%. It is a semisolid formulation dispensed through a pump mechanism, which allows for easy and precise application on the skin. The gel-like consistency ensures that the active ingredients are absorbed effectively into the targeted area for optimal therapeutic effect.

Amitriptyline is a tricyclic antidepressant that has been found to be effective in treating certain types of chronic pain, particularly neuropathic pain. It works by increasing the levels of certain chemicals in the brain that help improve mood, sleep, and the body's response to pain. When applied topically, Amitriptyline can provide targeted pain relief with fewer systemic side effects compared to oral administration.

Ketamine is a powerful anesthetic and analgesic that works by blocking the NMDA receptors in the brain, which play a key role in pain transmission. Topical application of Ketamine can provide localized pain relief, particularly for neuropathic pain conditions, without the systemic side effects associated with its oral or injectable use.

Lidocaine and Prilocaine are local anesthetics that work by blocking nerve signals in your body, providing temporary relief from pain and discomfort. They are commonly used in topical formulations to provide localized numbness, reducing pain and discomfort in the applied area.

This compounded formulation can be used to manage various disease states that involve chronic or neuropathic pain, such as post-herpetic neuralgia, diabetic neuropathy, and certain types of cancer pain. It can also be used in the management of localized painful conditions such as osteoarthritis. The combination of these four active ingredients provides a multi-modal approach to pain management, targeting different aspects of the pain pathway for a more comprehensive relief.

As with all medications, this formulation should be used as directed by a healthcare provider. Potential side effects may include skin irritation at the application site, and in rare cases, systemic side effects may occur. It is important to discuss any concerns or questions with your healthcare provider or pharmacist.

If you have any questions about this formulation, please do not hesitate to reach out to us at Bayview Pharmacy. Our team of knowledgeable compounding pharmacists is here to assist you.

This formulation combines Amitriptyline, Ketamine, Lidocaine, and Prilocaine in a topical gel. Each of these active ingredients has its own potential for drug interactions, which can be amplified when used in combination. It's important to be aware of these potential interactions to ensure safe and effective use of this medication.

Amitriptyline is a tricyclic antidepressant that can interact with a variety of medications, including other antidepressants, antipsychotics, antihistamines, and certain antifungal drugs. It can also interact with drugs that affect serotonin levels, such as selective serotonin reuptake inhibitors (SSRIs) and monoamine oxidase inhibitors (MAOIs), potentially leading to a serious condition called serotonin syndrome. Additionally, it can increase the effects of certain drugs that slow brain processes, such as alcohol, barbiturates, and benzodiazepines.

Ketamine is a powerful anesthetic that can interact with other anesthetics, as well as certain pain medications, sedatives, and drugs used for mental health conditions. It can also increase the effects of alcohol and other drugs that slow brain processes. Furthermore, it can interact with certain medications used for Parkinson's disease, seizure disorders, and high blood pressure.

Lidocaine and Prilocaine are local anesthetics that can interact with other local anesthetics, as well as certain heart medications. They can also increase the effects of drugs that slow brain processes, such as alcohol, barbiturates, and benzodiazepines.

This formulation is used topically, which can reduce the risk of systemic drug interactions. However, it's still important to be aware of potential interactions, especially if you're using other medications on the same area of skin. Additionally, this formulation can be absorbed into the bloodstream, particularly if used over large areas of skin or for extended periods of time, which can increase the risk of systemic interactions.

This formulation is typically used to treat conditions such as neuropathic pain, post-herpetic neuralgia, and other types of chronic pain. It works by numbing the skin and blocking pain signals in the nerves. The combination of active ingredients provides a multi-modal approach to pain management, targeting different aspects of the pain pathway for more effective relief.

If you have any questions about this formulation or its potential drug interactions, please don't hesitate to reach out to us. We're here to help ensure that you can use this medication safely and effectively.

This formulation combines four active ingredients: Amitriptyline, Ketamine, Lidocaine, and Prilocaine, each with its unique mechanism of action to provide relief from various disease states. The formulation is designed to be applied topically, directly to the skin, where it can be absorbed to provide targeted treatment.

Amitriptyline is a tricyclic antidepressant that works by increasing the levels of certain chemicals in the brain that help improve mood, relieve pain, and promote sleep. In this formulation, it is used for its analgesic properties to help manage chronic pain conditions. It is particularly effective in treating neuropathic pain, which is pain caused by damage to the nerves.

Ketamine is a powerful anesthetic that works by blocking the NMDA receptors in the brain, which play a role in pain sensation. By blocking these receptors, Ketamine can provide significant pain relief, particularly for conditions involving severe or chronic pain. It also has antidepressant effects, which can be beneficial for patients dealing with chronic pain and associated mood disorders.

Lidocaine and Prilocaine are local anesthetics that work by blocking sodium channels in the nerve cells, preventing the initiation and conduction of nerve impulses. This results in a numbing effect at the site of application, providing immediate relief from pain. These anesthetics are particularly effective in managing acute pain conditions, such as post-surgical pain or pain from minor injuries.

The combination of these four active ingredients in a gel formulation allows for easy and precise application to the skin. The gel is designed to be absorbed through the skin, delivering the active ingredients directly to the site of pain. This targeted approach can provide more effective pain relief with fewer systemic side effects compared to oral medications.

This formulation can be used to treat a variety of disease states, including chronic pain conditions, neuropathic pain, post-surgical pain, and pain associated with minor injuries. It can also be beneficial for patients dealing with mood disorders associated with chronic pain.

If you have any questions about this formulation, how it works, or how it can be used to treat specific conditions, please don't hesitate to reach out to us at Bayview Pharmacy. Our team of knowledgeable compounding pharmacists is always here to help.

Amitriptyline, Ketamine, Lidocaine, and Prilocaine are all active ingredients in this topical gel formulation, each having multiple uses beyond their primary indications. Amitriptyline, originally an antidepressant, sometimes is used topically due to its analgesic properties for the management of neuropathic pain. Equally, Ketamine offers similar benefits, especially regarding post-operative or chronic pain. Lidocaine and Prilocaine both are local anesthetics often utilized for minor skin procedures due to their numbing effect.

This formulation, though primarily used for pain relief, can find use in other areas as well due to the distinct properties of its constituents. For instance, since Amitriptyline and Ketamine both are known to have properties which can numb the neurological pain pathways, it is possible to use this formulation off-label for treating neuropathic pain conditions, such as post-herpetic neuralgia or diabetic peripheral neuropathy. Moreover, the presence of Lidocaine and Prilocaine makes the formulation useful for anesthetic induction before minor skin procedures or to alleviate pain due to burns or insect stings.

Beyond this, Lidocaine and Prilocaine could potentially relieve itching caused by skin conditions like eczema, psoriasis, or allergic reactions. Additionally, Ketamine, due to its antidepressant properties, could be used as a part of the treatment plan for severe depression or chronic pain syndromes when other treatments have failed, though under careful supervision.

However, it should be noted that all these other uses are off-label and should be used after a thorough discussion with the healthcare provider regarding the potentials risks, benefits, and alternatives. This particularly applies to individuals with existing medical conditions, pregnant or lactating women, and the elderly as they oftentimes exhibit heightened sensitivity to these primary ingredients.

Please remember, the use of pharmaceutical products should always be done under the guidance of a healthcare professional. If you have any further questions or concerns regarding the use of this formulation, do not hesitate to reach out to us at Bayview Pharmacy. We are here to help and guide you through your healthcare journey.