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Acyclovir 4%/Amitriptyline HCl 2%/Bupivacaine HCl 1%/2-Deoxy-D-Glucose 2%/Flurbiprofen 5%/Gabapentin 10% Topical Gel

FDA-approved generic
Dose form
Topical Gel
Active ingredients
Acyclovir
Amitriptyline Hydrochloride
Bupivacaine Hydrochloride
2-Deoxy-D-Glucose
Flurbiprofen
Gabapentin

This formulation is a compounded topical gel containing Acyclovir 4%, Amitriptyline HCl 2%, Bupivacaine HCl 1%, 2-Deoxy-D-Glucose 2%, Flurbiprofen 5%, and Gabapentin 10%. It is a semisolid formulation dispensed through a pump mechanism, which allows for easy and precise application on the skin. The gel-like consistency ensures targeted treatment or absorption of the active ingredients.

The formulation is designed to treat a variety of disease states. Acyclovir is an antiviral medication used to treat infections caused by certain types of viruses. Amitriptyline HCl is a tricyclic antidepressant used to treat symptoms of depression. Bupivacaine HCl is a local anesthetic used to numb specific areas of the body. 2-Deoxy-D-Glucose is a glucose molecule analog that is used in medical research. Flurbiprofen is a nonsteroidal anti-inflammatory drug (NSAID) used to treat pain or inflammation caused by arthritis. Gabapentin is an anti-epileptic drug, also called an anticonvulsant, that is used to treat nerve pain.

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For prescribers
Prescription details
RxThis formula
Dose formSee below
Quantity____
SigAs directed by prescriber
Refills____
PharmacyBayview Pharmacy, Warwick RI, NCPDP 4106882
Copy prescription detailsOrder form
Controlled substance: e-prescribe (EPCS) from your EHR. Faxed and phoned prescriptions cannot be accepted for this preparation.
Send it from your EHR, or fax to (401) 284-4506. How to e-prescribe this formula
Licensed to fill prescriptions for patients in RI, MA, CT, NJ, NH, FL, ME and PA. New York patients are served on a limited basis while nonresident registration is pending.
To prescribe, you must be a verified prescriber.
To prescribe, you must be in a state where we hold an active out-of-state pharmacy license.
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This medication requires a prescription from your doctor
Ships within 1 to 2 business days after pharmacist verification
HSA and FSA eligible
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Licensed to fill prescriptions for patients in RI, MA, CT, NJ, NH, FL, ME and PA. New York patients are served on a limited basis while nonresident registration is pending.

For prescribersSign in for prescription details and order forms.
Compounded preparations are prepared by Bayview pursuant to a prescription for an individual patient. They are not FDA-approved and have not been evaluated by FDA for safety or effectiveness.
Acyclovir
Amitriptyline Hydrochloride
Bupivacaine Hydrochloride
2-Deoxy-D-Glucose
Flurbiprofen
Gabapentin
Topical Gel
652f32759cf9684af16cbd9e
Service area

Can we ship this formula to your state?

Bayview fills prescriptions for patients in Connecticut, Florida, Maine, Massachusetts, New Hampshire, New Jersey, Pennsylvania and Rhode Island. New York patients are served on a limited basis while nonresident pharmacy registration is pending.

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Formula Information

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This formulation is a unique blend of six active ingredients: Acyclovir 4%, Amitriptyline HCl 2%, Bupivacaine HCl 1%, 2-Deoxy-D-Glucose 2%, Flurbiprofen 5%, and Gabapentin 10%. Each of these ingredients plays a crucial role in managing various disease states, and their combined effect in this topical gel formulation provides a comprehensive treatment approach.

Acyclovir is an antiviral medication used primarily to treat herpes simplex virus infections, reducing the pain and speeding up the healing of sores or blisters. Amitriptyline HCl is a tricyclic antidepressant that can also help relieve certain types of pain. Bupivacaine HCl is a local anesthetic, providing temporary numbness or loss of sensation in the area where the gel is applied.

2-Deoxy-D-Glucose is a glucose molecule analog that interferes with the metabolism of glucose, disrupting the growth of cancer cells. Flurbiprofen is a nonsteroidal anti-inflammatory drug (NSAID) that reduces inflammation and pain in the body. Gabapentin is an anticonvulsant and nerve pain medication used to treat seizures and pain caused by shingles.

When combined in a topical gel, these ingredients can provide targeted relief for a variety of conditions. The gel formulation allows for direct application to the affected area, reducing systemic side effects and improving patient compliance. The pump mechanism ensures easy and precise dosing.

This formulation can be used to manage conditions such as herpes infections, certain types of pain including neuropathic pain, localized areas of inflammation, and potentially certain types of cancer. It is important to note that the effectiveness of this formulation can vary depending on the individual patient's condition and response to treatment.

As with any medication, it is crucial to use this formulation under the guidance of a healthcare professional. Potential side effects can include skin irritation at the application site, and systemic side effects from each active ingredient. Always inform your healthcare provider of any other medications you are taking to avoid potential drug interactions.

If you have any questions about this formulation, please do not hesitate to reach out to us at Bayview Pharmacy. Our team of knowledgeable compounding pharmacists is here to assist you.

Drug Interactions

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This formulation contains a combination of Acyclovir, Amitriptyline HCl, Bupivacaine HCl, 2-Deoxy-D-Glucose, Flurbiprofen, and Gabapentin. Each of these active ingredients has its own potential for drug interactions, which can be increased when used in combination. It's important to note that this information is not exhaustive and other interactions may exist. Always consult with a healthcare provider for personalized advice.

Acyclovir, an antiviral medication, may interact with probenecid and tenofovir, potentially increasing the risk of kidney problems. Amitriptyline, a tricyclic antidepressant, can interact with MAO inhibitors, SSRIs, anticholinergics, and certain antihypertensives, potentially leading to serious side effects such as serotonin syndrome or hypertensive crisis.

Bupivacaine, a local anesthetic, may interact with certain antiarrhythmic drugs (like amiodarone), increasing the risk of serious heart problems. 2-Deoxy-D-Glucose, a glucose analog, has limited data on drug interactions but may potentially interact with antidiabetic medications. Flurbiprofen, a nonsteroidal anti-inflammatory drug (NSAID), can interact with anticoagulants, antiplatelet drugs, and other NSAIDs, increasing the risk of bleeding.

Gabapentin, an anticonvulsant and nerve pain medication, may interact with antacids, morphine, and hydrocodone, potentially affecting the absorption or efficacy of these drugs. It's also important to avoid alcohol while using this medication as it can increase the risk of side effects.

This formulation is designed to be applied topically, which can reduce the risk of systemic drug interactions. However, it's still important to inform your healthcare provider of all medications you're currently taking, including over-the-counter drugs, vitamins, and herbal supplements. This is to ensure the safe and appropriate use of this medication.

This formulation is used for the management of various disease states. Amitriptyline and Gabapentin are used for nerve pain management. Bupivacaine provides local anesthesia, while Flurbiprofen offers anti-inflammatory effects. 2-Deoxy-D-Glucose is being investigated for its potential anticancer and antiviral properties.

If you have any questions about this formulation or its potential interactions, please don't hesitate to reach out to us. We're here to provide you with the information you need to make informed decisions about your health.

How Does it Work

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This formulation is a combination of six active ingredients: Acyclovir, Amitriptyline HCl, Bupivacaine HCl, 2-Deoxy-D-Glucose, Flurbiprofen, and Gabapentin. Each of these ingredients plays a unique role in the treatment of various disease states.

Acyclovir is an antiviral medication that works by slowing the growth and spread of the herpes virus in the body. It is commonly used to treat outbreaks of herpes simplex on the skin, which can be caused by both the type 1 and type 2 strains of the virus. Acyclovir does not cure herpes, but it can lessen the symptoms of the infection.

Amitriptyline HCl is a tricyclic antidepressant that is often used in pain management. It works by increasing the levels of certain chemicals in the brain that help elevate mood and reduce the sensation of pain.

Bupivacaine HCl is a local anesthetic. It works by blocking nerve impulses in your body, thereby reducing pain and discomfort. It is often used for providing local anesthesia during surgical procedures, but in this formulation, it helps to provide topical pain relief.

2-Deoxy-D-Glucose is a glucose molecule which has the 2-hydroxyl group replaced by hydrogen, so that it cannot undergo further glycolysis. As such, it acts to inhibit glycolysis. It is used in this formulation for its potential antiviral and anticancer properties.

Flurbiprofen is a nonsteroidal anti-inflammatory drug (NSAID). It works by reducing hormones that cause inflammation and pain in the body. It is used in this formulation to reduce inflammation and provide pain relief.

Gabapentin is a drug used to treat nerve pain and seizures. It works by calming down nerve activity, thereby reducing pain and discomfort. In this formulation, it is used to provide topical relief from nerve pain.

This formulation is dispensed through a pump mechanism, which allows for easy and precise application on the skin. The active ingredients are absorbed through the skin, providing targeted treatment for the affected area. This can be particularly beneficial for patients who have difficulty swallowing pills or who prefer not to take medication orally.

If you have any questions about this formulation, please don't hesitate to reach out to us. We are here to help and provide you with the information you need to make informed decisions about your health.

Other Uses

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This compound formulation consisting of Acyclovir, Amitriptyline HCl, Bupivacaine HCl, 2-Deoxy-D-Glucose, Flurbiprofen, and Gabapentin bears potential for other applications beyond its primary indication. These components individually exhibit a wide range of therapeutic properties that could be employed in the management of various ailments when combined in a topical gel vehicle.

Acyclovir, an antiviral agent, may be used in treating localized manifestations of herpes infection, while its combination with the neuropathic pain-relieving Gabapentin and Bupivacaine HCl, a local anesthetic, could provide relief for postherpetic neuralgia, a persistent pain following herpes zoster infection. Amitriptyline HCl, a tricyclic antidepressant, is utilized for treating neuropathic pain and various forms of chronic pain, and could, therefore, potentially extend the spectrum of pathologies that this formulation serves. The addition of Flurbiprofen, a nonsteroidal anti-inflammatory drug, suggests utility in treating localized inflammation and associated pain.

Moreover, 2-Deoxy-D-Glucose, implicated in cancer studies for its ability to interfere with glucose metabolism of cancer cells, could potentially render the topical compound important in localized treatment or prevention of skin neoplasms. It's crucial to note however that such application requires further research and approval from bodies such as the FDA.

Beyond these, the soothing, semisolid formulation dispensed via a pump mechanism could be adapted for dermatological use such as moisturizers or emollients, providing symptomatic relief for conditions like eczema, dry skin, or minor skin irritations. However, the use of this formulation in this manner should be guided by a healthcare provider to prevent potential mishaps, particularly because most of these ingredients might require prescription.

Sensitive populations such as pregnant or breastfeeding women, those with damaged or broken skin, and those with known allergies to the ingredients, should take caution or seek medical advice before using this formulation. As is with any medication, it is important to be mindful of potential side effects such as skin irritation, local numbness, or systemic effects like dizziness or upset stomach.

This topical formulation developed at Bayview Pharmacy shows promise in treating a variety of conditions. However, further research is needed to confirm additional benefits and ascertain the best practices for use outside its primary indication. For any questions or concerns about this formulation, feel free to reach out to us directly.

Frequently Asked Questions

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What is the composition of the compounded formulation?

The compounded formulation includes Acyclovir 4%, Amitriptyline HCl 2%, Bupivacaine HCl 1%, 2-Deoxy-D-Glucose 2%, Flurbiprofen 5%, and Gabapentin 10%.

What is the texture of this formulation?

This is a semisolid formulation with a gel-like consistency. It's easy to apply on the skin for targeted treatment.

How can I apply this compounded formulation?

The formulation is dispensed through a pump mechanism, which facilitates easy and precise application on the skin. Just press the pump and apply the dispensed product over the affected area.

Can this formulation be used for any skin type?

Most skin types should not have a problem with this formulation. However, if you have sensitive skin or skin allergies, it is a good idea to consult your healthcare provider before use.

Is this compounded formulation topical?

Yes, this formulation is a topical gel intended for application on the skin.

What does each component of the formulation do?

Each component in this formulation is a medication to treat different conditions. Acyclovir is an antiviral, Amitriptyline is used for its analgesic properties, Bupivacaine is a local anesthetic, 2-Deoxy-D-Glucose has potential anti-inflammatory and anticancer properties, Flurbiprofen is a nonsteroidal anti-inflammatory, and Gabapentin is used for neuropathic pain relief.

Can this formulation be used for pain relief?

Yes, the compounded formulation includes Amitriptyline, Bupivacaine, and Gabapentin, which are known to provide pain relief.

How long should I leave the gel on my skin?

Generally the gel is designed to be absorbed by your skin. Follow your healthcare provider's advice regarding duration of application for optimal results.

Are there any precautions when using this gel formulation?

Avoid contact with eyes and mouth. If the gel accidentally gets into these areas, please rinse with plenty of water. Also, do not apply on broken or irritated skin.

Should I wash my hands after applying?

Yes, it's recommended that you wash your hands immediately after applying the gel to avoid accidental contact with eyes or ingestion of the medication.

About this compounded preparation

This formulation is compounded by Bayview Pharmacy on a prescriber's order for an individual patient. It is not an FDA-approved drug product, and the FDA has not evaluated it for safety, effectiveness, or manufacturing quality.

The conditions listed on this page are indications prescribers have ordered this preparation for. They are not FDA-approved indications, and listing them is not a statement that this preparation is effective for them.

A valid prescription is required. Availability depends on Bayview's licensure in your state. This page is general information, not medical advice — discuss your situation with a licensed healthcare provider.

Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.

No compounded medications are reviewed by the FDA for safety or efficacy.
For prescribers

How to e-prescribe this formula

Controlled substance: e-prescribe only (EPCS). Faxed, phoned, and handwritten prescriptions cannot be filled. Rhode Island law (R.I. Gen. Laws § 21-28-3.18) requires Schedule II to V prescriptions to be transmitted electronically.
1

Find Bayview in your EHR's pharmacy directory

Search by NCPDP 4106882, or by name and ZIP: Bayview Pharmacy, Warwick, RI 02886. Select it as the destination pharmacy and save it as a favorite. Click any value to copy it.

NCPDP4106882NPI1750455143Address3844 Post Rd, Warwick, RI 02886Phone(401) 284-4505Fax(401) 284-4506
2

Enter the formula as a compound

Compounded preparations have no NDC, so this formula will not appear in your EHR's drug search. Use your system's compound, non-formulary, or free-text prescription entry and name the preparation exactly as written in step 3. If your EHR forces you to pick a listed drug, pick the closest entry for the active ingredient and put the full formula in the prescription body (the Sig or directions field), not in Notes to Pharmacy.

Compounded preparations have no NDC and will not appear in your drug search. For EPCS to validate, select a drug entry your EHR recognizes as controlled, usually the bulk powder entry for the active ingredient (for example Ketamine (bulk) powder, not a branded product), then put the full formula from step 3 in the prescription body. A free-text entry that does not validate as controlled will be rejected by your EPCS module.

3

Copy the prescription details

RxFormula name
Dose formDose form
Quantity________
SigAs directed by prescriber
Refills____
PharmacyBayview Pharmacy, Warwick RI, NCPDP 4106882
Copy prescription details

Quantity and directions are starting points for this dose form, not treatment recommendations. Dosing remains the prescriber's responsibility.

4

Send it

Transmit from your EHR. For this non-controlled preparation we also accept fax to (401) 284-4506 and phoned orders at (401) 284-4505. Order forms are on the formulation pages and in the prescriber portal.

Transmit with two-factor authentication through your EPCS-enabled EHR. No order form is offered for this preparation; e-prescribing guides for our controlled preparations are on the formulation pages.

Do not use Notes to Pharmacy for the formula. Some EHRs keep that field internal and never transmit it. A prescription that arrives without the formula is delayed while we call your office.

Licensed to dispense in RI, MA, CT, NJ, NH, FL, ME, and PA; New York is served on a limited basis while nonresident registration is pending. Compounded preparations are not FDA-approved. A valid prescription is required. Full guide, including steps by EHR: How to e-prescribe to Bayview. Questions about this formula: call (401) 284-4505.

Acyclovir 4%/Amitriptyline HCl 2%/Bupivacaine HCl 1%/2-Deoxy-D-Glucose 2%/Flurbiprofen 5%/Gabapentin 10% Topical Gel
Topical Gel
60 g
controlled

Apply topically to affected area(s)

Three times daily